Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Silke Reiffert"'
Autor:
Rivka Adar, Dirk Waldherr, Christine Rothe, Sarit Kotzer, Titus Kretzschmar, Achim Knappik, Elisabeth Thomassen-Wolf, Susanne Bauer, Michael Malka, Eran Rom, Yael Yaniv, Irina Chumakov, Silke Reiffert, Robert Rauchenberger, Avner Yayon, Dalia Resnitzky, Karin Jury, Josef Prassler, Eric Borges
Publikováno v:
The Journal of biological chemistry. 278(40)
The human combinatorial antibody library Fab 1 (HuCAL®-Fab 1) was generated by transferring the heavy and light chain variable regions from the previously constructed single-chain Fv library (Knappik, A., Ge, L., Honegger, A., Pack, P., Fischer, M.,
Autor:
Eva M. Schier, Bernd Hubner, Silke Reiffert, Matt Dunn, Benno Rattel, Stefan Zahn, Kurt Lobenwein, Mark G. Wing, Corinna Löhning, Michael Tesar, Zoltan Nagy, Titus Kretzschmar, Michael Stanglmaier, Steve Anderson, Angelika Zahradnik, Sigmar Leyer, Elisabeth Thomassen-Wolf, Christoph Brunner, Robert Rauchenberger, Michael Hallek
Publikováno v:
Nature medicine. 8(8)
The Human Combinatorial Antibody Library (HuCAL) was screened for antibodies specific to human leukocyte antigen-DR (HLA-DR) that induce programmed death of lymphoma/leukemia cells expressing the target antigen. The active Fab fragments were affinity
Autor:
Matthias Marget, Peter Söhlemann, Landon Inge, Achim Knappik, Christine Rothe, Manqiu Cao, Xian-Qin Meng, Joachim Wölle, Jill Winter, Robert Rauchenberger, Elisabeth Thomassen, Peter Pack, Adolf Höß, Titus Kretzschmar, Torsten Dreier, Silke Reiffert, Barbara Krebs, David Fischer, Michael Tesar, Robert Schier
Publikováno v:
Journal of immunological methods. 254(1-2)
The first version of the Human Combinatorial Antibody Library (HuCAL) is a single-chain Fv-based phage display library (HuCAL-scFv) with 2x10(9) members optimised for high-throughput generation and targeted engineering of human antibodies. 61% of the