Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Silke Nicklisch"'
CU-2010—A Novel Small Molecule Protease Inhibitor with Antifibrinolytic and Anticoagulant Properties
Autor:
Andreas Koster, Helmut Giersiefen, Wulf Dietrich, Andreas van de Locht, Silke Nicklisch, Michael Spannagl
Publikováno v:
Anesthesiology. 110:123-130
Background In cardiac surgery, the contact of blood with the artificial surfaces of the cardiopulmonary bypass results in activation of coagulation, fibrinolysis, and platelets, which is recognized as reason for increased bleeding tendency. Antifibri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0dc87a1ac6d1c40e5e1dbb6417ad35a
https://doi.org/10.1097/aln.0b013e318191408c
https://doi.org/10.1097/aln.0b013e318191408c
Autor:
Daniel Dönnecke, Torsten Steinmetzer, Maj Schuster, Anne Stürzebecher, Uta Stürzebecher, Silke Nicklisch, Andrea Schweinitz, Peter Steinmetzer, Jörg Stürzebecher
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(12)
Highly potent and selective substrate analogue factor Xa inhibitors were obtained by incorporation of non-basic or modestly basic P1 residues known from the development of thrombin inhibitors. The modification of the P2 and P3 amino acids strongly in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912b9fa751f6838214066b0d23da00ab
https://pubmed.ncbi.nlm.nih.gov/17462889
https://pubmed.ncbi.nlm.nih.gov/17462889
Autor:
Christiane Gläser, Andualem Mossie, Volker Steger, Christiane Pockelt, Klaus Huse, Silke Nicklisch, Ulli Sack, Sunna Hauschildt, Gerd Birkenmeier, Michael Bauer, Elke Usbeck, Angelika Schäfer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 318(2)
A drug targeting both the inflammatory initiators (lipopolysaccharide; LPS) and mediators [tumor necrosis factor-alpha (TNF-alpha)] should have advantage over a "single-factor targeting strategy" in sepsis prevention trials. We have prepared conjugat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c81e9938474aea45333d50060f1136
https://pubmed.ncbi.nlm.nih.gov/16705081
https://pubmed.ncbi.nlm.nih.gov/16705081
Autor:
Michael Hecker, Silke Nicklisch, Thomas Nietsche, Antje Gupta, Christian Schwahn, Peter Neubauer, Sylke Meyer, Stephan Riemschneider, Renate Hanschke, Raymond Jarchow, H. Y. Lin
Publikováno v:
Recombinant Protein Production with Prokaryotic and Eukaryotic Cells. A Comparative View on Host Physiology ISBN: 9789048157563
Changes in the physiology of Escherichia coli cells producing a recombinant α-glucosidase were studied in glucose limited fed-batch fermentations. High α-glucosidase formation is connected to growth inhibition and loss of culturability. Although so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5de4546d165f1ea09d2bae937bd35f6f
https://doi.org/10.1007/978-94-015-9749-4_5
https://doi.org/10.1007/978-94-015-9749-4_5
