Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Silke Neumann"'
Autor:
Nicholas J. Shields, Estelle M. Peyroux, Angela L. Ferguson, Megan Steain, Silke Neumann, Sarah L. Young
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/40c9f9365f9c40efb8d32419af6af5f0
Autor:
Amit Sharma, Diogo C. Fernandes, Rui L. Reis, Dominika Gołubczyk, Silke Neumann, Barbara Lukomska, Miroslaw Janowski, Marcin Kortylewski, Piotr Walczak, J. Miguel Oliveira, Jarek Maciaczyk
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract The blood–brain barrier (BBB) is a sophisticated structure whose full functionality is required for maintaining the executive functions of the central nervous system (CNS). Tight control of transport across the barrier means that most drug
Externí odkaz:
https://doaj.org/article/8501d0a072824dcf8d51d5f71cc023f1
Autor:
Jim Mann, Sean Coffey, Huan Chan, Robin Turner, Alastair Ross, Ross Wilson, Fiona Hood, Ella Iosua, Andrew N Reynolds, Silke Neumann, Rajesh Katare, Aysu Shahin, Zi-yi Kok
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction Coronary heart disease is a major contributor to the global burden of disease. Appropriate nutrition is a cornerstone of the prevention and treatment of coronary heart disease; however, barriers including cost and access to recommended f
Externí odkaz:
https://doaj.org/article/c26b4826a8e841069d3b46ad5c763c58
Autor:
Nicholas J. Shields, Estelle M. Peyroux, Angela L. Ferguson, Megan Steain, Silke Neumann, Sarah L. Young
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Anti-tumour T cell responses play a crucial role in controlling the progression of colorectal cancer (CRC), making this disease a promising candidate for immunotherapy. However, responses to immune-targeted therapies are currently limited to subpopul
Externí odkaz:
https://doaj.org/article/676903a2a65f412380f4a0a4a1213509
Autor:
Suad Yusuf, Philippe Aretz, Ann-Christin Nickel, Philipp Westhoff, Amit Sharma, Nan Qin, Marc Remke, Hans-Jakob Steiger, Daniel Hänggi, Hongjia Liu, Hongde Liu, Silke Neumann, Guido Reifenberger, Jarek Maciaczyk
Publikováno v:
Cancers, Vol 14, Iss 13, p 3165 (2022)
Isocitrate dehydrogenase (IDH)-wildtype glioblastoma is the most common primary malignant brain tumor. It is associated with a particularly poor prognosis, as reflected by an overall median survival of only 15 months in patients who undergo a suprama
Externí odkaz:
https://doaj.org/article/2e7f2ccd6e4b4291b0a1be0ef844850b
Autor:
Philippe Aretz, Donata Maciaczyk, Suad Yusuf, Rüdiger V. Sorg, Daniel Hänggi, Hongjia Liu, Hongde Liu, Tikam Chand Dakal, Amit Sharma, Ramakrishna Bethanabatla, Silke Neumann, Jarek Maciaczyk
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4562 (2022)
Isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GBM) is a fast growing and highly heterogeneous tumor, often characterized by the presence of glioblastoma stem cells (GSCs). The plasticity of GSCs results in therapy resistance and impairs anti-
Externí odkaz:
https://doaj.org/article/fcb15ce0d84c40ab8af0e39e1773f8bc
Autor:
Silke Neumann, Lily Boothman-Burrell, Emma K. Gowing, Thomas A. Jacobsen, Philip K. Ahring, Sarah L. Young, Karin Sandager-Nielsen, Andrew N. Clarkson
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Inflammatory processes are known to contribute to tissue damage in the central nervous system (CNS) across a broad range of neurological conditions, including stroke. Gamma amino butyric acid (GABA), the main inhibitory neurotransmitter in the CNS, h
Externí odkaz:
https://doaj.org/article/16eebc1f4f9344f5b5c5ecb61734f3f8
Autor:
Silke Neumann, Katrin Campbell, Matthew J. Woodall, Meghan Evans, Andrew N. Clarkson, Sarah L. Young
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8803 (2021)
Obesity is a major risk factor for developing cancer, with obesity-induced immune changes and inflammation in breast (BC) and colorectal cancer (CRC) providing a potential link between the two. This study investigates systemic effects of obesity on a
Externí odkaz:
https://doaj.org/article/5b4657b9e62444cda36323a56c1cff1f
Autor:
Julia Tsiampali, Silke Neumann, Beatriz Giesen, Katharina Koch, Donata Maciaczyk, Christoph Janiak, Daniel Hänggi, Jaroslaw Maciaczyk
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 378 (2020)
Glioblastoma (GBM) is the most aggressive malignant primary brain tumour in adulthood. Despite strong research efforts current treatment options have a limited impact on glioma stem-like cells (GSCs) which contribute to GBM formation, progression and
Externí odkaz:
https://doaj.org/article/0a002d75bddb4b26929821b23563c844
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29029-29046 (2015)
Stroke is one of the leading causes of death and long-term disability, with limited treatment options available. Inflammation contributes to damage tissue in the central nervous system across a broad range of neuropathologies, including Alzheimer’s
Externí odkaz:
https://doaj.org/article/023308ad431a4084ac1dd29b32ac1f42