Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Silke Muehlau"'
Autor:
Kathrin Schersch, Silke Muehlau, Stefan Bassarab, Ortrud Betz, Patrick Garidel, Gerhard Winter
Publikováno v:
Journal of Pharmaceutical Sciences. 101:2288-2306
The objective of this work was to investigate the effect of lyophilizate collapse on the stability of freeze-dried protein pharmaceuticals. In the first part of this study, it was shown that collapse has no negative impact either on the properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0140379c5ee09e0a703def0abd6f2272
https://doi.org/10.1002/jps.23121
https://doi.org/10.1002/jps.23121
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85(2)
This study investigates the effect of lyophilizate collapse on the stability of pharmaceutical proteins. Recently, it was shown that collapse during freeze-drying has no major negative impact on protein stability during storage at elevated temperatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f25d19ee6e1e870e5bfe66f15e63394
https://pubmed.ncbi.nlm.nih.gov/23727369
https://pubmed.ncbi.nlm.nih.gov/23727369
Autor:
Patrick Garidel, Wolfgang Friess, Silke Muehlau, Virginie Le Brun, Torsten Schultz-Fademrecht
Publikováno v:
Biotechnology journal. 4(9)
The purpose of the presented study is to understand the physicochemical properties of proteins in aqueous solutions in order to identify solution conditions with reduced attractive protein-protein interactions, to avoid the formation of protein aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e911a4ab94453c359eb1a7056ce38309
https://pubmed.ncbi.nlm.nih.gov/19579219
https://pubmed.ncbi.nlm.nih.gov/19579219