Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Silke Metz"'
Autor:
Britta Schneider, Michael Grote, Matthias John, Alexander Haas, Birgit Bramlage, Ludger M lckenstein, Kerstin Jahn-Hofmann, Frieder Bauss, Weijun Cheng, Rebecca Croasdale, Karin Daub, Simone Dill, Eike Hoffmann, Wilma Lau, Helmut Burtscher, James L Ludtke, Silke Metz, Olaf Mundigl, Zane C Neal, Werner Scheuer, Jan Stracke, Hans Herweijer, Ulrjch Brinkmann
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Bispecific antibodies (bsAbs) that bind to cell surface antigens and to digoxigenin (Dig) were used for targeted small interfering RNA (siRNA) delivery. They are derivatives of immunoglobulins G (IgGs) that bind tumor antigens, such as Her2, IGF1-R,
Externí odkaz:
https://doaj.org/article/6bec11c8644d43c8bfff095546e986f7
Publikováno v:
Nursing Open, Vol 10, Iss 4, Pp 2229-2239 (2023)
Abstract Aim To identify personal beliefs of Dutch nursing staff about encouraging psychogeriatric nursing home residents in daily activities. Design Qualitative study following COREQ guidelines. Methods Fifteen semi‐structured interviews with Dutc
Externí odkaz:
https://doaj.org/article/87232bcae8e64d0193720068c0dcb285
Autor:
Christian Panke, Eike Hoffmann, Wilma Lau, Pablo Umana, Britta Schneider, Birgit Bossenmaier, Ulrich Brinkmann, Johannes Auer, Christian Gassner, Alexander Haas, Claudio Sustmann, Jürgen Michael Schanzer, Rebecca Croasdale, Silke Metz
Publikováno v:
Protein Engineering, Design and Selection
We have designed bispecific antibodies that bind one target (anti-Her3) in a bivalent IgG-like manner and contain one additional binding entity (anti-cMet) composed of one V(H) and one V(L) domain connected by a disulfide bond. The molecules are asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9c6f24e09dc6a32eea0763bfd6ea18
http://europepmc.org/articles/PMC3449404
http://europepmc.org/articles/PMC3449404
Autor:
Silke Metz, Heike Lauks, Monique Y. Wiesinger, Michael Vogt, Peter C. Heinrich, Günther Schmalzing, Gerhard Müller-Newen
Publikováno v:
Journal of Biological Chemistry. 282:1238-1248
Although fusion proteins of the extracellular parts of receptor subunits termed cytokine traps turned out to be promising cytokine inhibitors for anti-cytokine therapies, their mode of action has not been analyzed. We developed a fusion protein consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29c13634cdd6021e39205ab2818d45f7
https://doi.org/10.1074/jbc.m606885200
https://doi.org/10.1074/jbc.m606885200
Autor:
Stan Vluggen, Silke Metzelthin, Valeria Lima Passos, Sandra Zwakhalen, Getty Huisman-de Waal, Janneke de Man-van Ginkel
Publikováno v:
BMC Nursing, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Nurses are in a key position to stimulate older people to maximize their functional activity and independence. However, nurses still often work in a task-oriented manner and tend to take over tasks unnecessarily. It is evident to
Externí odkaz:
https://doaj.org/article/1c3059db556a4193b9bd8b4a2c227e1b
Publikováno v:
Journal of Biological Chemistry. 279:15114-15123
The transcription factor STAT3 is most important for the signal transduction of interleukin-6 and related cytokines. Upon stimulation cytoplasmic STAT3 is phosphorylated at tyrosine 705, translocates into the nucleus, and induces target genes. Notabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5366f6136e2ea640b4d04950ec91fb
https://doi.org/10.1074/jbc.m312530200
https://doi.org/10.1074/jbc.m312530200
Autor:
Silke Metz, Eike Hoffmann, Weijun Cheng, Kerstin Jahn-Hofmann, Jan Olaf Stracke, Werner Scheuer, Britta Schneider, Olaf Mundigl, Hans Herweijer, Wilma Lau, Simone Dill, Matthias John, Ludger M lckenstein, Karin Daub, Zane C. Neal, Michael Grote, James Ludtke, Rebecca Croasdale, Frieder Bauss, Alexander Haas, Helmut Burtscher, Birgit Bramlage, Ulrjch Brinkmann
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Bispecific antibodies (bsAbs) that bind to cell surface antigens and to digoxigenin (Dig) were used for targeted small interfering RNA (siRNA) delivery. They are derivatives of immunoglobulins G (IgGs) that bind tumor antigens, such as Her2, IGF1-R,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb0d21ca8c5f857cf9217edf1aa26a8
Autor:
Werner Scheuer, Alexander Haas, Ulrich Brinkmann, Wilma Lau, Eike Hoffmann, Jan Olaf Stracke, Guy Georges, Hans-Peter Josel, Silke Metz, Sebastian Dziadek, Karin Daub, Karl-Peter Hopfner, Olaf Mundigl, Alfred Lammens, Rebecca Croasdale
Bispecific antibodies that bind cell-surface targets as well as digoxigenin (Dig) were generated for targeted payload delivery. Targeting moieties are IgGs that bind the tumor antigens Her2, IGF1R, CD22, or LeY. A Dig-binding single-chain Fv was atta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22c48931160b3a6fd29a493f625764e
https://europepmc.org/articles/PMC3100918/
https://europepmc.org/articles/PMC3100918/
Publikováno v:
The Journal of biological chemistry. 283(10)
Fusion proteins of the extracellular parts of cytokine receptors, also known as cytokine traps, turned out to be promising cytokine inhibitors useful in anti-cytokine therapies. Here we present newly designed cytokine traps for murine and human leuke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b241bdbacf644f5e22c5659912bdf4cb
https://pubmed.ncbi.nlm.nih.gov/18174171
https://pubmed.ncbi.nlm.nih.gov/18174171
Autor:
Silke, Metz, Monique, Wiesinger, Michael, Vogt, Heike, Lauks, Günther, Schmalzing, Peter C, Heinrich, Gerhard, Müller-Newen
Publikováno v:
The Journal of biological chemistry. 282(2)
Although fusion proteins of the extracellular parts of receptor subunits termed cytokine traps turned out to be promising cytokine inhibitors for anti-cytokine therapies, their mode of action has not been analyzed. We developed a fusion protein consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b069b2f193acb00a34200618d98864d1
https://pubmed.ncbi.nlm.nih.gov/17085445
https://pubmed.ncbi.nlm.nih.gov/17085445