Confocal Real-Time Analysis of Cutaneous Platelet Recruitment during Immune Complex‒Mediated Inflammation

Autor: Silke M. Currie, Rebekka I. Stegmeyer, Karina Mildner, Leonhard Breitsprecher, Dagmar Zeuschner, Olympia Ekaterini Psathaki, Kerstin Schäfer, Markus Wilkens, Stefan Volkery, Bernhard Nieswandt, Dietmar Vestweber

Publikováno v: The Journal of investigative dermatology. 142(10)

Platelets preserve vascular integrity during immune complex‒mediated skin inflammation by preventing neutrophil-provoked hemorrhage. However, the single-cell dynamics of this hemostatic process have never been studied in real-time. To monitor the o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77dffb7b59dfc0f033f61a4485cc98a8
https://pubmed.ncbi.nlm.nih.gov/35987718

Cathelicidins Have Direct Antiviral Activity against Respiratory Syncytial Virus In Vitro and Protective Function In Vivo in Mice and Humans

Autor: Jürgen Schwarze, Emily Gwyer Findlay, Allan Paras, Agnieszka Jozwik, Amanda J. McFarlane, Christopher Chiu, Nick Colegrave, Donald J. Davidson, Paul M. Fitch, Silke M. Currie, Bettina Böttcher

Publikováno v: The Journal of Immunology Author Choice
Currie, S M, Gwyer Findlay, E, McFarlane, A, Fitch, P, Boettcher, A, Colegrave, N, Paras, A, Jozwik, A, Chiu, C, Schwarze, J & Davidson, D J 2016, ' Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans. ', Journal of Immunology, vol. 196, no. 6, pp. 2699-2710 . https://doi.org/10.4049/jimmunol.1502478

Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infection in infants, causing significant morbidity and mortality. No vaccine or specific, effective treatment is currently available. A more complete understanding of the key

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbe88c17e90ab2dd9324d22ce75a4ac
http://europepmc.org/articles/PMC4777919

The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus

Autor: Donald J. Davidson, Emily Gwyer Findlay, Paul M. Fitch, Jürgen Schwarze, Hongwei Wang, Annie Mackellar, Tian Man, Brian J. McHugh, Derek Macmillan, Silke M. Currie

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e73659 (2013)
PLoS ONE
Currie, S M, Gwyer Findlay, E, McHugh, B J, Mackellar, A, Man, T, Macmillan, D, Wang, H, Fitch, P M, Schwarze, J & Davidson, D J 2013, ' The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus ', PLoS ONE, vol. 8, no. 8, e73659 . https://doi.org/10.1371/journal.pone.0073659

Respiratory syncytial virus is a leading cause of lower respiratory tract illness among infants, the elderly and immunocompromised individuals. Currently, there is no effective vaccine or disease modifying treatment available and novel interventions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c245cea07e55023680dc969a176cd798
https://doi.org/10.1371/journal.pone.0073659

Landmark-based retrieval of inflamed skin vessels enabled by 3D correlative intravital light and volume electron microscopy.

Autor: Mildner, Karina¹ (AUTHOR), Breitsprecher, Leonhard² (AUTHOR), Currie, Silke M.³ (AUTHOR), Stegmeyer, Rebekka I.³ (AUTHOR), Stasch, Malte⁴ (AUTHOR), Volkery, Stefan⁴ (AUTHOR), Psathaki, Olympia Ekaterini² (AUTHOR), Vestweber, Dietmar³ (AUTHOR), Zeuschner, Dagmar¹ (AUTHOR) D.Zeuschner@mpi-muenster.mpg.de

Publikováno v: Histochemistry & Cell Biology. Aug2022, Vol. 158 Issue 2, p127-136. 10p.

The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus.

Autor: Currie, Silke M.¹, Findlay, Emily Gwyer¹, McHugh, Brian J.¹, Mackellar, Annie¹, Man, Tian^1,2, Macmillan, Derek³, Wang, Hongwei^1,4, Fitch, Paul M.¹, Schwarze, Jürgen¹, Davidson, Donald J.¹ donald.davidson@ed.ac.uk

Publikováno v: PLoS ONE. Aug2013, Vol. 8 Issue 8, p1-10. 10p.