Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Silke Lassman"'
Autor:
Susana Minguet, Rubí Velasco Cárdenas, Simon Brandl, Emilia Schlaak, Annabelle Buschky, Timo Peters, Fabian Beier, Bryan Serrels, Sanaz Taromi, Katrin Raute, Simon Hauri, Matthias Gstaiger, Silke Lassman, Johannes Huppa, Melanie Boerries, Geoffroy Andrieux, Bertram Bengsch, Wolfgang Schamel
Current FDA-approved CAR T cells harbour the TCR-derived ζ chain as intracellular activation domain. The contribution of the other chains of the TCR complex, namely CD3δ, CD3ε, and CD3γ in a CAR format remains unknown. Here, we have systematicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec2eee5a3c1138410063f621ef7dade
https://doi.org/10.21203/rs.3.rs-2378631/v1
https://doi.org/10.21203/rs.3.rs-2378631/v1
Autor:
Julia C. Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesús Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L. Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H. Heiland, Roman Sankowski, Florian Scherer
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Despite major advances in molecular profiling and classification of primary brain tumors, personalized treatment remains limited for most patients. Here, we explored the feasibility of individual molecular profiling and the efficacy of bioma
Externí odkaz:
https://doaj.org/article/1dc07143d8964d58a48d87e8eab4e848
Autor:
Michaela A. Ihle, Carina Heydt, Anne Maria Schultheis, Robert Stöhr, Florian Haller, Sylvia Herold, Daniela Aust, Wolfgang Dietmaier, Matthias Evert, Markus Eszlinger, Anja Haak, Silke Laßmann, Daniela Vorholt, Frank Breitenbücher, Martin Werner, Anna Streubel, Thomas Mairinger, Maja Grassow-Narlik, Sabine Merkelbach-Bruse
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Insertion mutations in exon 20 of the epidermal growth factor receptor gene (EGFR exon20ins) are rare, heterogeneous alterations observed in non-small cell lung cancer (NSCLC). With a few exceptions, they are associated with primary resistan
Externí odkaz:
https://doaj.org/article/9fbf9687d08840bb993f42908b606080
Autor:
Michael Menzel, Stephan Ossowski, Sebastian Kral, Patrick Metzger, Peter Horak, Ralf Marienfeld, Melanie Boerries, Steffen Wolter, Markus Ball, Olaf Neumann, Sorin Armeanu-Ebinger, Christopher Schroeder, Uta Matysiak, Hannah Goldschmid, Vincent Schipperges, Axel Fürstberger, Michael Allgäuer, Timo Eberhardt, Jakob Niewöhner, Andreas Blaumeiser, Carolin Ploeger, Tobias Bernd Haack, Timothy Kwang Yong Tay, Olga Kelemen, Thomas Pauli, Martina Kirchner, Klaus Kluck, Alexander Ott, Marcus Renner, Jakob Admard, Axel Gschwind, Silke Lassmann, Hans Kestler, Falko Fend, Anna Lena Illert, Martin Werner, Peter Möller, Thomas Theodor Werner Seufferlein, Nisar Malek, Peter Schirmacher, Stefan Fröhling, Daniel Kazdal, Jan Budczies, Albrecht Stenzinger
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract A growing number of druggable targets and national initiatives for precision oncology necessitate broad genomic profiling for many cancer patients. Whole exome sequencing (WES) offers unbiased analysis of the entire coding sequence, segmenta
Externí odkaz:
https://doaj.org/article/c80cfb96a9be48f6bbb8329e92275143
Autor:
Silvia Waldeck, Jan Mitschke, Sebastian Wiesemann, Michael Rassner, Geoffroy Andrieux, Max Deuter, Jurik Mutter, Anne‐Marie Lüchtenborg, Daniel Kottmann, Laurin Titze, Christoph Zeisel, Martina Jolic, Ulrike Philipp, Silke Lassmann, Peter Bronsert, Christine Greil, Justyna Rawluk, Heiko Becker, Lisa Isbell, Alexandra Müller, Soroush Doostkam, Bernward Passlick, Melanie Börries, Justus Duyster, Julius Wehrle, Florian Scherer, Nikolas von Bubnoff
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 527-537 (2022)
Circulating tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess minimal residual disease (MRD) and profile tumor genotypes in patients with non‐small‐cell lung cancer (NSCLC). However, little is known about its
Externí odkaz:
https://doaj.org/article/4399d10b1bd049f3a353a6cfadf469f6
Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer
Autor:
Emna Sakka, Yuko Shimizu, Axel zur Hausen, Mario Sarbia, Martin Werner, Anja Schöpflin, Tadamasa Ooka, Elisabeth Nikolopoulos, Timo Heidt, Thorsten Wiech, Silke Lassman
Publikováno v:
Virchows Archiv : an international journal of pathology. 452(6)
Approximately 10% of gastric carcinomas (GC) worldwide are associated with Epstein–Barr virus (EBV). GC is one of the most frequent human malignancies associated with EBV. The latent expression of the EBV-oncogene BARF1 is restricted to epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b43c95969badaaa186dc0c7ce118618
https://pubmed.ncbi.nlm.nih.gov/18437417
https://pubmed.ncbi.nlm.nih.gov/18437417
Autor:
Thorsten Wiech, Elisabeth Nikolopoulos, Silke Lassman, Timo Heidt, Anja Schöpflin, Martin Werner, Emna Sakka, Tadamasa Ooka, Axel zur Hausen, Wiech, Thorsten, Nikolopoulos, Elisabeth, Lassman, Silke, Heidt, Timo, Schöpflin, Anja, Sarbia, Mario, Werner, Martin, Shimizu, Yuko, Sakka, Emna, Ooka, Tadamasa, zur Hausen, Axel
Publikováno v:
Virchows Archiv: European Journal of Pathology; Jun2008, Vol. 452 Issue 6, p621-627, 7p
Autor:
Florian Weinberg, Nadine Reischmann, Lisa Fauth, Sanaz Taromi, Justin Mastroianni, Martin Köhler, Sebastian Halbach, Andrea C. Becker, Niantao Deng, Tatjana Schmitz, Franziska Maria Uhl, Nicola Herbener, Bianca Riedel, Fabian Beier, Alexander Swarbrick, Silke Lassmann, Jörn Dengjel, Robert Zeiser, Tilman Brummer
Publikováno v:
EBioMedicine, Vol 20, Iss C, Pp 79-97 (2017)
Despite being overexpressed in different tumor entities, RIO kinases are hardly characterized in mammalian cells. We investigated the role of these atypical kinases in different cancer cells. Using isogenic colon-, breast- and lung cancer cell lines,
Externí odkaz:
https://doaj.org/article/32fd6546823d4e5fa47b9bb4b923d4d0