Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Silke Hornemann"'
Autor:
Michael Kruse, Silke Hornemann, Anne-Cathrin Ost, Turid Frahnow, Daniela Hoffmann, Andreas Busjahn, Martin A. Osterhoff, Bettina Schuppelius, Andreas F. H. Pfeiffer
Publikováno v:
Nutrients, Vol 15, Iss 10, p 2338 (2023)
Background: The dysfunction of energy metabolism in white adipose tissue (WAT) induces adiposity. Obesogenic diets that are high in saturated fat disturb nutrient metabolism in adipocytes. This study investigated the effect of an isocaloric high-fat
Externí odkaz:
https://doaj.org/article/798227b33ab3463aafc921390112daea
Autor:
Anastasia Georgiadi, Valeria Lopez-Salazar, Rabih El- Merahbi, Rhoda Anane Karikari, Xiaochuan Ma, André Mourão, Katarina Klepac, Lea Bühler, Ana Jimena Alfaro, Isabell Kaczmarek, Adam Linford, Madeleen Bosma, Olga Shilkova, Olli Ritvos, Nobuhiro Nakamura, Shigehisa Hirose, Maximilian Lassi, Raffaele Teperino, Juliano Machado, Marcel Scheideler, Arne Dietrich, Arie Geerlof, Annette Feuchtinger, Andreas Blutke, Katrin Fischer, Timo Dirk Müller, Katharina Kessler, Torsten Schöneberg, Doreen Thor, Silke Hornemann, Michael Kruse, Peter Nawroth, Olga Pivovarova-Ramich, Andreas Friedrich Hermann Pfeiffer, Michael Sattler, Matthias Blüher, Stephan Herzig
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
The soluble bioactive form of the transmembrane protein fibronectin type III domain containing 4 (sFNDC4) has anti-inflammatory effects and improves insulin sensitivity. Here the authors show that liver derived sFNDC4 signals through adipose tissue G
Externí odkaz:
https://doaj.org/article/899459e9671c4eeca6889de131d50098
Autor:
Stefan Kabisch, Mariya Markova, Silke Hornemann, Stephanie Sucher, Olga Pivovarova-Ramich, Jürgen Machann, Johannes Hierholzer, Sascha Rohn, Andreas F. H. Pfeiffer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Non-alcoholic fatty liver disease (NAFLD) is common in Metabolic Syndrome and type 2 diabetes (T2DM), driven by energy imbalance, saturated fats and simple carbohydrates. NAFLD requires screening and monitoring for late complications. Liver
Externí odkaz:
https://doaj.org/article/8487ee657cc844dfa87948c21f423a06
Autor:
Jiudan Zhang, Olga Pivovarova-Ramich, Stefan Kabisch, Mariya Markova, Silke Hornemann, Stephanie Sucher, Sascha Rohn, Jürgen Machann, Andreas F. H. Pfeiffer
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Glucagon (GCGN) plays a key role in glucose and amino acid (AA) metabolism by increasing hepatic glucose output. AA strongly stimulate GCGN secretion which regulates hepatic AA degradation by ureagenesis. Although increased fasting GCGN levels cause
Externí odkaz:
https://doaj.org/article/fdf76eeff074409e803efe375c940465
Autor:
Olga Pivovarova-Ramich, Mariya Markova, Daniela Weber, Stephanie Sucher, Silke Hornemann, Natalia Rudovich, Jens Raila, Daniele Sunaga-Franze, Sascha Sauer, Sascha Rohn, Andreas F.H. Pfeiffer, Tilman Grune
Publikováno v:
Redox Biology, Vol 29, Iss , Pp - (2020)
High-protein diet is a promising strategy for diabetes treatment supporting body weight control, improving glycaemic status, cardiovascular risk factors and reducing liver fat. Here, we investigated effects of diets high in animal (AP) or plant (PP)
Externí odkaz:
https://doaj.org/article/389475fe800b4de698ee8c86ab0c9ed4
Autor:
Rita Schüler, Nicole Seebeck, Martin A. Osterhoff, Veronica Witte, Agnes Flöel, Andreas Busjahn, Alexander Jais, Jens C. Brüning, Turid Frahnow, Stefan Kabisch, Olga Pivovarova, Silke Hornemann, Michael Kruse, Andreas F.H. Pfeiffer
Publikováno v:
Molecular Metabolism, Vol 11, Iss , Pp 129-136 (2018)
Objective: Reduction of brain glucose transporter GLUT1 results in severe neurological dysfunction. VEGF is required to restore and maintain brain glucose uptake across the blood brain barrier via GLUT1, which was shown to be acutely diminished in re
Externí odkaz:
https://doaj.org/article/2005e01fdb524ae387b71c65eaf84927
Autor:
Olga Pivovarova-Ramich, Jennifer Loske, Silke Hornemann, Mariya Markova, Nicole Seebeck, Anke Rosenthal, Frederick Klauschen, José Pedro Castro, René Buschow, Tilman Grune, Volker Lange, Natalia Rudovich, D. Margriet Ouwens
Publikováno v:
Cells, Vol 10, Iss 5, p 1048 (2021)
Liver fibrosis is a critical complication of obesity-induced fatty liver disease. Wnt1 inducible signaling pathway protein 1 (WISP1/CCN4), a novel adipokine associated with visceral obesity and insulin resistance, also contributes to lung and kidney
Externí odkaz:
https://doaj.org/article/0511f3018cd14fd6b75df1ec3e243ec7
Autor:
Rita Schüler, Martin A. Osterhoff, Turid Frahnow, Matthias Möhlig, Joachim Spranger, Darko Stefanovski, Richard N. Bergman, Li Xu, Anne-Cathrin Seltmann, Stefan Kabisch, Silke Hornemann, Michael Kruse, Andreas F. H. Pfeiffer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract The frequent ACE insertion/deletion polymorphism (I/D) is, albeit inconsistently, associated with impaired glucose tolerance and insulin resistance. We recently observed an enhanced upregulation of ACE by elevated fat intake in GG-carriers o
Externí odkaz:
https://doaj.org/article/0913f2fc8a184fa1805fcb5bc6470a62
Autor:
Turid Frahnow, Martin A. Osterhoff, Silke Hornemann, Michael Kruse, Michal A. Surma, Christian Klose, Kai Simons, Andreas F. H. Pfeiffer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Lipidomics have a great potential as clinical tool for monitoring metabolic changes in health and disease. Nevertheless hardly anything is known about the heritability of lipids. Therefore, it is necessary to clarify how and how much we can
Externí odkaz:
https://doaj.org/article/0457bd64ab80427fad165d8dfe28746c
Autor:
Liselot Koelman, Mariya Markova, Nicole Seebeck, Silke Hornemann, Anke Rosenthal, Volker Lange, Olga Pivovarova-Ramich, Krasimira Aleksandrova
Publikováno v:
Nutrients, Vol 12, Iss 12, p 3636 (2020)
Nutritional interventions in morbidly obese individuals that effectively reverse a pro-inflammatory state and prevent obesity-associated medical complications are highly warranted. Our aim was to evaluate the effect of high (HP) or low (LP) protein d
Externí odkaz:
https://doaj.org/article/45be31aa5a454cd2afd0e9c0be50b12c