Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Silke Gerlach"'
Autor:
Thi-Phuong Tao, Ilka Maschmeyer, Edward L. LeCluyse, Eda Rogers, Katrin Brandmair, Silke Gerlach, Julia Przibilla, Fredy Kern, Camille Genies, Carine Jacques, Abdulkarim Najjar, Andreas Schepky, Uwe Marx, Jochen Kühnl, Nicola J. Hewitt
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
All cosmetic ingredients registered in Europe must be evaluated for their safety using non-animal methods. Microphysiological systems (MPS) offer a more complex higher tier model to evaluate chemicals. Having established a skin and liver HUMIMIC Chip
Externí odkaz:
https://doaj.org/article/5068186205ee485da21ca6a4409cc5d3
Autor:
Ilka Maschmeyer, Julia Przibilla, Thi Phuong Tao, Camille Genies, Carine Jacques-Jamin, Andreas Schepky, Uwe Marx, Katrin Brandmair, Nicola J. Hewitt, Jochen Kühnl, Silke Gerlach
Publikováno v:
Journal of Applied Toxicology. 41:1553-1567
We used TissUse's HUMIMIC Chip2 microfluidic model, incorporating reconstructed skin models and liver spheroids, to investigate the impact of consumer-relevant application scenarios on the metabolic fate of the hair dye, 4-amino-2-hydroxytoluene (AHT
Autor:
Nadine Karschuk, Yeliz Tepe, Silke Gerlach, Wolfgang Pape, Horst Wenck, Robert Schmucker, Klaus-Peter Wittern, Andreas Schepky, Hendrik Reuter
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15221 (2010)
Photoactivation and binding of photoactive chemicals to proteins is a known prerequisite for the formation of immunogenic photoantigens and the induction of photoallergy. The intensive use of products and the availability of new chemicals, along with
Externí odkaz:
https://doaj.org/article/a22fb3870067405691136310396f456b
Autor:
Uwe Marx, Camille Genies, Julia Przibilla, Silke Gerlach, Nicola J. Hewitt, Thamée Rings, Katrin Brandmair, Ursula Müller-Vieira, Thi Phuong Tao, Ilka Maschmeyer, Jochen Kühnl, Andreas Schepky, Carine Jaques-Jamin
Publikováno v:
Toxicology. 448:152637
Microphysiological systems (MPS) aim to mimic the dynamic microenvironment and the interaction between tissues. While MPS exist for investigating pharmaceuticals, the applicability of MPS for cosmetics ingredients is yet to be evaluated. The HUMIMIC
Autor:
Valentin Graeff, Alexander Roitenberg, Barbara Stollfuß, Sabine Berghaus, Frank Kleinjung, Silke Gerlach, Manuel J. Richter, Ardeschir Ghofrani, Christian Müller
Publikováno v:
16. Deutscher Kongress für Versorgungsforschung (DKVF); 20171004-20171006; Berlin; DOCP100 /20170926/
Ventavis is an effective therapy for patients with PAH, improving exercise capacity and symptoms. Ventavis nebuliser solution for inhalation is available as 10 µg/mL (V10) and 20 µg/mL (V20) formulations, administered using the I-Neb nebulizer. Som
Autor:
Marie Templier, Petra Winkler, Jochem Spieker, Claire Mangez, Silke Gerlach, Hendrik Reuter, Andreas Schepky, Pierre Aeby, Horst Wenck, Cindy A. Ryan, Aurelien Mignot, Caroline Bauch, Frank Gerberick, Robert Landsiedel
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 29(5)
Allergic contact dermatitis is a delayed T-cell mediated allergic response associated with relevant social and economic impacts. Animal experiments (e.g. the local lymph node assay) are still supplying most of the data used to assess the sensitizatio
Autor:
Silke Gerlach, Robert Dr. Schmucker, Klaus-Peter Wittern, Andreas Schepky, Yeliz Tepe, Nadine Karschuk, Hendrik Reuter, Wolfgang Pape, Horst Wenck
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e15221 (2010)
PLoS ONE, Vol 5, Iss 12, p e15221 (2010)
Photoactivation and binding of photoactive chemicals to proteins is a known prerequisite for the formation of immunogenic photoantigens and the induction of photoallergy. The intensive use of products and the availability of new chemicals, along with
Autor:
Andreas Schepky, Klaus-Peter Wittern, Walter Diembeck, Wolfgang Pape, Silke Gerlach, Kerstin Reisinger, Horst Wenck, Jochem Spieker, Ursula Engels, Hendrik Reuter, Ludger Kolbe, Robert Dr. Schmucker
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 25(1)
Allergic contact dermatitis is a delayed T-cell mediated allergic response associated with relevant social and economic impacts. Animal experiments (e.g. the local lymph node assay) are still supplying most of the data used to assess the sensitizatio
Publikováno v:
Investigative radiology. 35(8)
RATIONALE AND OBJECTIVES Intravenous injection of liposomes is able to trigger allergy-like reactions that affect the cardiopulmonary system. The mechanism of these effects is still not totally clear. Because prediction of adverse reactions and the c
Publikováno v:
The Journal of Immunology. 190:201.5-201.5
Allergic contact dermatitis is a delayed T-cell mediated allergic response associated with relevant social and economic impacts. Until now, animal experiments (e.g. the local lymph node assay) are supplying most of the data used to assess the sensiti