Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Silke Frey"'
Autor:
Darja Andreev, Katerina Kachler, Mengdan Liu, Zhu Chen, Brenda Krishnacoumar, Mark Ringer, Silke Frey, Gerhard Krönke, David Voehringer, Georg Schett, Aline Bozec
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Eosinophils are involved in tissue homeostasis. Herein, we unveiled eosinophils as important regulators of bone homeostasis. Eosinophils are localized in proximity to bone-resorbing osteoclasts in the bone marrow. The absence of eosinophils
Externí odkaz:
https://doaj.org/article/5da2f219e2984371a8d14992bdd17d44
Autor:
Silke Frey, Linda Kerkemeyer
Publikováno v:
Digital Health, Vol 8 (2022)
Objective On the way to a modern digital healthcare system, Germany becomes a driver of innovation by integrating digital health applications (Digitale Gesundheitsanwendungen (DiGAs)) into standard care. Although all insured persons of the statutory
Externí odkaz:
https://doaj.org/article/22c437323ffb49b09f50fd31662af05f
Autor:
Dmytro Royzman, Darja Andreev, Lena Stich, Katrin Peckert-Maier, Andreas B. Wild, Elisabeth Zinser, Petra Mühl-Zürbes, Evan Jones, Susanne Adam, Silke Frey, Maximilian Fuchs, Meik Kunz, Tobias Bäuerle, Lisa Nagel, Georg Schett, Aline Bozec, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and OC-Stamp were strongly reduced, while Foxp
Externí odkaz:
https://doaj.org/article/576ad5b73c124cb0990703d4d392cc97
Autor:
Jutta Ries, Abbas Agaimy, Falk Wehrhan, Christoph Baran, Stella Bolze, Eva Danzer, Silke Frey, Jonathan Jantsch, Tobias Möst, Maike Büttner-Herold, Claudia Wickenhauser, Marco Kesting, Manuel Weber
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 194 (2021)
Background: The programmed cell death ligand 1/programmed cell death receptor 1 (PD-L1/PD-1) Immune Checkpoint is an important modulator of the immune response. Overexpression of the receptor and its ligands is involved in immunosuppression and the f
Externí odkaz:
https://doaj.org/article/5ea5a0a50b9e43beb2c5d2b67279fa3c
Autor:
Olga Kurow, Benjamin Frey, Louis Schuster, Verena Schmitt, Susanne Adam, Madelaine Hahn, Derek Gilchrist, Iain B. McInnes, Stefan Wirtz, Udo S. Gaipl, Gerhard Krönke, Georg Schett, Silke Frey, Axel J. Hueber
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The interleukin (IL)-1 family member IL-33 has been described as intracellular alarmin with broad roles in wound healing, skin inflammation but also autoimmunity. Its dichotomy between full length (fl) IL-33 and the mature (m) form of IL-33 and its r
Externí odkaz:
https://doaj.org/article/8337a0be8e654bb7a6654583aa6c3463
Autor:
Anja Derer, Bettina Groetsch, Ulrike Harre, Christina Böhm, Jennifer Towne, Georg Schett, Silke Frey, Axel J Hueber
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e101954 (2014)
INTRODUCTION: Interleukin (IL)-36α is a newly described member of the IL-1 cytokine family with a known inflammatory and pathogenic function in psoriasis. Recently, we could demonstrate that the receptor (IL-36R), its ligand IL-36α and its antagoni
Externí odkaz:
https://doaj.org/article/0f4e842f23ba451d8eec20a2a2e2cc17
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20003 (2011)
BACKGROUND:Naturally occurring CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cells develop in the thymus and represent a mature T cell subpopulation critically involved in maintaining peripheral tolerance. The differentiation of Treg cells in the thymus
Externí odkaz:
https://doaj.org/article/57c011f347d0486ab5d80f591271256d
Autor:
Odilia B. J. Corneth, Merlijn H Kaaij, Job Saris, Leonie M. van Duivenvoorde, Martijn A. Nolte, Desiree Pots, Yik Y Kan, Georg Schett, Silke Frey, Joep Grootjans, Kim C. M. Jeucken, Jan Piet van Hamburg, Jasper Rip, Sander W. Tas, Rudi W. Hendriks, Charlotte C N van Rooijen, Dominique Baeten
Publikováno v:
Journal of Immunology, 207(9), 2337-2346. American Association of Immunologists
Journal of immunology (Baltimore, Md., 207(9), 2337-2346. American Association of Immunologists
Journal of immunology (Baltimore, Md., 207(9), 2337-2346. American Association of Immunologists
TNF is important in immune-mediated inflammatory diseases, including spondyloarthritis (SpA). Transgenic (tg) mice overexpressing transmembrane TNF (tmTNF) develop features resembling human SpA. Furthermore, both tmTNF tg mice and SpA patients develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64eb8e99b73d2105a7b28deb4c105098
https://pure.eur.nl/en/publications/0249f58e-3488-4515-99df-408d1880f51f
https://pure.eur.nl/en/publications/0249f58e-3488-4515-99df-408d1880f51f
Autor:
Ramadurai Ramachandran, Ajay Abisheck Paul George, Oliver Ohlenschläger, Toni Kühl, Kerstin Galler, Amit Kumar, Nishit Goradia, Ute Neugebauer, Patrick Hoffmann, Stefan H. Heinemann, Iqbal Hamza, Silke Frey, Susanne Adam, Jürgen Popp, Gerhard Krönke, Amelie Wißbrock, Axel J. Hueber, Kornelia Hampel, Maximilian Wiendl, Peter Bellstedt, Bastian Zimmermann, Diana Imhof
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Cytokines of the interleukin (IL)-1 family regulate immune and inflammatory responses. The recently discovered IL-36 family members are involved in psoriasis, rheumatoid arthritis, and pulmonary diseases. Here, we show that IL-36α interacts with hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80a7ab04c07f63bbab941a1df367943
http://link.springer.com/article/10.1038/s41598-019-53231-0
http://link.springer.com/article/10.1038/s41598-019-53231-0
Publikováno v:
Journal of Cellular Immunology. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ba0bd19a9c2c3d24aa90c16c3484b92
https://doi.org/10.33696/immunology.3.075
https://doi.org/10.33696/immunology.3.075