Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Silke Fähnrich"'
Optimized for routine: highly sensitive fluorescent Telomeric Repeat Amplification Protocol (f-TRAP)
Publikováno v:
BioTechniques, Pp 1-6 (2024)
The strict suppression of telomerase activity (TA) in terminally differentiated human cells causes a shortening of the chromosome ends after each cell division. This tumor suppression surveillance mechanism is associated with a limited number of cell
Externí odkaz:
https://doaj.org/article/f19a13cc80a3453aaa77b8dd377b50b5
Autor:
Silke Fähnrich, Roderick A. F. MacLeod, Hans G. Drexler, Maren Kaufmann, Stefan Nagel, Corinna Meyer, Claudia Pommerenke
Publikováno v:
Oncotarget
Recently, we have presented a scheme, termed “NKL-code”, which describes physiological expression patterns of NKL homeobox genes in early hematopoiesis and in lymphopoiesis including main stages of T-, B- and NK-cell development. Aberrant activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3395165ca9cdc7c6e3aca043fcb6a5e
http://europepmc.org/articles/PMC6524933
http://europepmc.org/articles/PMC6524933
Autor:
Hans G. Drexler, Vivien Hauer, Margarete Zaborski, Hilmar Quentmeier, Silke Fähnrich, Wilhelm G. Dirks, Claudia Pommerenke, Cord C. Uphoff
Publikováno v:
Leukemia Research. 88:106270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef612ee083922526772c71a97f6ce53
https://doi.org/10.1016/j.leukres.2019.106270
https://doi.org/10.1016/j.leukres.2019.106270
Autor:
Hans G. Drexler, Wilhelm G. Dirks, Christian Mielke, Silke Fähnrich, Kurt E.J. Dittmar, Lennart M. Roesner, Yvonne Merkhoffer
Publikováno v:
Journal of Cellular Biochemistry. 114:2405-2414
The human DNA mismatch repair (MMR) gene family comprises four MutL paralogues capable of forming heterodimeric MutLα (MLH1-PMS2), MutLβ (MLH1-PMS1), and MutLγ (MLH1-MLH3) protein complexes. Human MutL subunits PMS2 and MLH3 contain an evolutionar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70dd7dbee3d4ff96e9bcfa989aa1c9ba
https://doi.org/10.1002/jcb.24591
https://doi.org/10.1002/jcb.24591
Autor:
Silke Fähnrich, Michael Pawlita, Markus Schmitt, Agnes Hotz-Wagenblatt, Felipe A. Castro, Wilhelm G. Dirks
Publikováno v:
International Journal of Cancer. 132:308-314
Use of false cell lines remains a major problem in biological research. Short tandem repeat (STR) profiling represents the gold standard technique for cell line authentication. However, mismatch repair (MMR)-deficient cell lines are characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d380a325d8d0a4c3866962bdce520ce8
https://doi.org/10.1002/ijc.27675
https://doi.org/10.1002/ijc.27675
Autor:
Silke Fähnrich, Hans G. Drexler, Yvonne Lis, Roderick A.F. MacLeod, Elisabeth Becker, W. G. Dirks
Publikováno v:
International Journal of Cancer. 100:49-56
The initial identification of the ALK gene, expressed as C-terminal part of the transforming fusion protein NPM-ALK in the t(2;5)(p23;q35) lymphoma-associated chromosomal translocation, revealed a novel receptor tyrosine kinase (RTK). In order to exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3cf5adc14358ce17a8b3ddd387f774
https://doi.org/10.1002/ijc.10435
https://doi.org/10.1002/ijc.10435
Autor:
Lennart M, Roesner, Christian, Mielke, Silke, Fähnrich, Yvonne, Merkhoffer, Kurt E J, Dittmar, Hans G, Drexler, Wilhelm G, Dirks
Publikováno v:
Journal of cellular biochemistry. 114(10)
The human DNA mismatch repair (MMR) gene family comprises four MutL paralogues capable of forming heterodimeric MutLα (MLH1-PMS2), MutLβ (MLH1-PMS1), and MutLγ (MLH1-MLH3) protein complexes. Human MutL subunits PMS2 and MLH3 contain an evolutionar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f06b6ec5da1ef754f8c7222ad2f02869
https://pubmed.ncbi.nlm.nih.gov/23696135
https://pubmed.ncbi.nlm.nih.gov/23696135
Autor:
Willy G, Dirks, Silke, Fähnrich, Yvonne, Lis, Elisabeth, Becker, Roderick A F, MacLeod, Hans G, Drexler
Publikováno v:
International journal of cancer. 100(1)
The initial identification of the ALK gene, expressed as C-terminal part of the transforming fusion protein NPM-ALK in the t(2;5)(p23;q35) lymphoma-associated chromosomal translocation, revealed a novel receptor tyrosine kinase (RTK). In order to exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f93efd8883e5816110d91273805d5ef6
https://pubmed.ncbi.nlm.nih.gov/12115586
https://pubmed.ncbi.nlm.nih.gov/12115586