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pro vyhledávání: '"Silke Brunholz"'
Autor:
Svenja König, Nadine Schmidt, Karin Bechberger, Sarah Morris, Mercedes Priego, Hannah Zaky, Yuyu Song, Jan Pielage, Silke Brunholz, Scott T. Brady, Stefan Kins, Gerardo Morfini
Publikováno v:
Cells, Vol 12, Iss 19, p 2403 (2023)
The amyloid precursor protein (APP) is a key molecular component of Alzheimer’s disease (AD) pathogenesis. Proteolytic APP processing generates various cleavage products, including extracellular amyloid beta (Aβ) and the cytoplasmic APP intracellu
Externí odkaz:
https://doaj.org/article/6703bde0bb5c498e83438eabd66e9cf8
Autor:
Silke Brunholz, Stefan Kins, Carole Deyts, Alfredo Lorenzo, Sangram S. Sisodia, Gerardo Morfini
Publikováno v:
Experimental brain research. 217(3-4)
Over two decades have passed since the original discovery of amyloid precursor protein (APP). While physiological function(s) of APP still remain a matter of debate, consensus exists that the proteolytic processing of this protein represents a critic