Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Silke Bergeler"'
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION Addressing practical challenges in clinical practice after the recent approvals of amyloid antibodies in Alzheimer's disease (AD) will benefit more patients. However, generating these answers using clinical trials or real‐worl
Externí odkaz:
https://doaj.org/article/f30ec32ba1eb40edbfcdb39739561400
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Misfolded proteins in Alzheimer’s disease and Parkinson’s disease follow a well-defined connectomics-based spatial progression. Several anti-tau and anti-alpha synuclein (aSyn) antibodies have failed to provide clinical benefit in clinic
Externí odkaz:
https://doaj.org/article/1baaa5025ae842fab4f3f4ffb5de510a
Autor:
Jessica L. Verpeut, Silke Bergeler, Mikhail Kislin, F. William Townes, Ugne Klibaite, Zahra M. Dhanerawala, Austin Hoag, Sanjeev Janarthanan, Caroline Jung, Junuk Lee, Thomas J. Pisano, Kelly M. Seagraves, Joshua W. Shaevitz, Samuel S.-H. Wang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract The cerebellum regulates nonmotor behavior, but the routes of influence are not well characterized. Here we report a necessary role for the posterior cerebellum in guiding a reversal learning task through a network of diencephalic and neocor
Externí odkaz:
https://doaj.org/article/7160c3afc36a42c19ff9f54f35d500d3
Autor:
Hugo Geerts, Mike Walker, Rachel Rose, Silke Bergeler, Piet H. van derGraaf, Edgar Schuck, Akihiko Koyama, Sanae Yasuda, Ziad Hussein, Larisa Reyderman, Chad Swanson, Antonio Cabal
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 4, Pp 444-461 (2023)
Abstract Antibody‐mediated removal of aggregated β‐amyloid (Aβ) is the current, most clinically advanced potential disease‐modifying treatment approach for Alzheimer's disease. We describe a quantitative systems pharmacology (QSP) approach of
Externí odkaz:
https://doaj.org/article/d9e08080706b49e386d73cb4a04cf07d
Autor:
Ugne Klibaite, Mikhail Kislin, Jessica L. Verpeut, Silke Bergeler, Xiaoting Sun, Joshua W. Shaevitz, Samuel S.-H. Wang
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background Repetitive action, resistance to environmental change and fine motor disruptions are hallmarks of autism spectrum disorder (ASD) and other neurodevelopmental disorders, and vary considerably from individual to individual. In anima
Externí odkaz:
https://doaj.org/article/68412c67206b4e4d84aeff8ae23f09cf
Publikováno v:
eLife, Vol 10 (2021)
Cell division site positioning is precisely regulated but the underlying mechanisms are incompletely understood. In the social bacterium Myxococcus xanthus, the ~15 MDa tripartite PomX/Y/Z complex associates with and translocates across the nucleoid
Externí odkaz:
https://doaj.org/article/8ec155bdd465426cb263fe89c4ddc1b7
Autor:
Silke Bergeler, Erwin Frey
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 8, p e1006358 (2018)
Precise positioning of the cell division site is essential for the correct segregation of the genetic material into the two daughter cells. In the bacterium Myxococcus xanthus, the proteins PomX and PomY form a cluster on the chromosome that performs
Externí odkaz:
https://doaj.org/article/b08a87ad796948b38c88593cce1321e9
Misfolded proteins in Alzheimer’s disease (AD) and Parkinson’s disease (PD) follow a well-defined connectomics-based spatial progression. Several anti-tau and anti-alpha synuclein (aSyn) antibodies have failed to provide clinical benefit in clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d625c6765b966dcae04d3cf509bc632
https://doi.org/10.21203/rs.3.rs-2799205/v1
https://doi.org/10.21203/rs.3.rs-2799205/v1
Autor:
Chanchala Kaddi, Mengdi Tao, Silke Bergeler, Randolph Leiser, Mike Walker, Hugo Geerts, Kelly George, Catherine Wilson, Catherine Ortemann-Renon, Atef Zaher, Susana Zaph
Publikováno v:
Molecular Genetics and Metabolism. 138:107174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5724044dd32690179126252ce616c872
https://doi.org/10.1016/j.ymgme.2022.107174
https://doi.org/10.1016/j.ymgme.2022.107174
Autor:
Jessica L. Verpeut, Silke Bergeler, Mikhail Kislin, F. William Townes, Ugne Klibaite, Zahra M. Dhanerawala, Austin Hoag, Caroline Jung, Junuk Lee, Thomas J. Pisano, Kelly M. Seagraves, Joshua W. Shaevitz, Samuel S.-H. Wang
The cerebellum regulates nonmotor behavior, but the routes by which it exerts its influence are not well characterized. Here we report a necessary role for the posterior cerebellum in guiding a reversal learning task, acting through a network of dien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ed2597659ed83560992bcb6ded0576
https://doi.org/10.1101/2021.12.07.471685
https://doi.org/10.1101/2021.12.07.471685