Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Silke, Rinkwitz"'
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5944 (2009)
To better understand how individual genes and experience influence behavior, the role of a single homeotic unit, hoxb4a, was comprehensively analyzed in vivo by clonal and retrograde fluorescent labeling of caudal hindbrain neurons in a zebrafish enh
Externí odkaz:
https://doaj.org/article/cafc9f2d37724a3091f3cb7c1af89e06
Publikováno v:
Human Molecular Genetics. 25:1728-1738
Spinal muscular atrophy (SMA) is an autosomal recessive disease linked to survival motor neuron (SMN) protein deficiency. While SMN protein is expressed ubiquitously, its deficiency triggers tissue-specific hallmarks, including motor neuron death and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5372bf71c70bb64a3466ee17aa5dbc7
https://doi.org/10.1093/hmg/ddw044
https://doi.org/10.1093/hmg/ddw044
Autor:
Ahmed Abu-Siniyeh, Silke Rinkwitz, Carola Benzing, Thomas Becker, Arindam Majumdar, Katharina Gaus, Dylan M. Owen
Publikováno v:
Traffic. 17:66-79
The differential distribution of lipids between apical and basolateral membranes is necessary for many epithelial cell functions, but how this characteristic membrane organization is integrated within the polarity network during ductal organ developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a41f5878a7098a199554a7b87986b517
https://doi.org/10.1111/tra.12339
https://doi.org/10.1111/tra.12339
Autor:
Elizabeth Manning, Maximiliano L. Suster, Fan‐Suo Geng, Koichi Kawakami, Silke Rinkwitz, Thomas Becker
Publikováno v:
Genesis (New York, N.y. : 2000)
Summary Single Nucleotide Polymorphisms in FTO intron 1 have been associated with obesity risk, leading to the hypothesis that FTO is the obesity‐related gene. However, other studies have shown that the FTO gene is part of the regulatory domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ce2bf1e5771dceff369a956412abb7
https://doi.org/10.1002/dvg.22884
https://doi.org/10.1002/dvg.22884
Publikováno v:
Developmental Neurobiology. 76:507-518
During early development of the central nervous system (CNS), a subset of yolk-sac derived myeloid cells populate the brain and provide the seed for the microglial cell population, which will self-renew throughout life. As development progresses, ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdae515b2f750408aa58ec96eae8e14b
https://doi.org/10.1002/dneu.22328
https://doi.org/10.1002/dneu.22328
Publikováno v:
genesis. 53:321-328
miR218-1 and miR218-2 are embedded in introns of SLIT2 and SLIT3, respectively, an arrangement conserved throughout vertebrate genomes. Both miR218 genes are predicted to be transcribed in the same orientation as their host genes and were assumed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3244dd78cd233f75cc946f428f28c72a
https://doi.org/10.1002/dvg.22852
https://doi.org/10.1002/dvg.22852
Autor:
Kristy C. Yuan, Adam J. Svahn, Maxinne Watchon, Nick Mackovski, Angela S. Laird, Garth A. Nicholson, Claire Goldsbury, Thomas Becker, Silke Rinkwitz, Nicholas J. Cole
The neurodegenerative disease Machado–Joseph disease (MJD), also known as spinocerebellar ataxin-3, affects neurons of the brain and spinal cord, disrupting control of the movement of muscles. We have successfully established the first transgenic z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d528a5dc0014f83570beeac147b141e5
https://europepmc.org/articles/PMC6596655/
https://europepmc.org/articles/PMC6596655/
Activity of etv5a and etv5b genes in the hypothalamus of fasted zebrafish is influenced by serotonin
Serotonin has been implicated in the inhibition of food intake in vertebrates. However, the mechanisms through which serotonin acts has yet to be elucidated. Recently, ETV5 (ets variant gene 5) has been asso- ciated with obesity and food intake contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8de270b322f2a07cac6f7695b02698
https://www.sciencedirect.com/science/article/pii/S0016648016303392
https://www.sciencedirect.com/science/article/pii/S0016648016303392
Publikováno v:
Zebrafish. 10:447-450
Our zebrafish colony experienced a period of increased mortality rate of 6.5 times more deaths per month in a colony of over 13,000 zebrafish (Danio rerio), which developed over 3 months. We observed that before death, affected fish appeared emaciate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919fa7f7e7a7136ad0ec7d4b6a20bc96
https://doi.org/10.1089/zeb.2013.0868
https://doi.org/10.1089/zeb.2013.0868
Autor:
Adam J. Svahn, Silke Rinkwitz, Felix Ellett, Graham J. Lieschke, Max R. Bennett, Thomas Becker, Manuel B. Graeber
Publikováno v:
Developmental Neurobiology. 73:60-71
Microglia, the resident macrophage precursors of the brain, are necessary for the maintenance of tissue homeostasis and activated by a wide range of pathological stimuli. They have a key role in immune and inflammatory responses. Early microglia stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005f17834a789707901336a053cf1e0b
https://doi.org/10.1002/dneu.22039
https://doi.org/10.1002/dneu.22039