Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Silke, Reischl"'
Autor:
Christian H. Gabriel, Marta del Olmo, Amin Zehtabian, Marten Jäger, Silke Reischl, Hannah van Dijk, Carolin Ulbricht, Asylkhan Rakhymzhan, Thomas Korte, Barbara Koller, Astrid Grudziecki, Bert Maier, Andreas Herrmann, Raluca Niesner, Tomasz Zemojtel, Helge Ewers, Adrián E. Granada, Hanspeter Herzel, Achim Kramer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Live-cell recordings have been an important tool for studying circadian rhythms. Here the authors use CRISPR gene editing mediated knock-in to fluorescently tag Per2 and Cry1, and study cellular circadian dynamics of these two clock proteins.
Externí odkaz:
https://doaj.org/article/b3b650cbf5af40ee9a15a843fab1524b
Autor:
Chandrasekhar Kanduri, Tanmoy Mondal, John Inge Johnsen, Matthias Fischer, Per Kogner, Maite Huarte, Leo Kurian, Ivan Raimondi, Santhilal Subhash, Daniel Jachimowicz, Silke Reischl, Subazini Thankaswamy Kosalai, Prasanna Kumar Juvvuna, Mirco Di Marco, Somsundar Veppil Muralidharan, Sanhita Mitra
Supplementary Text, Supplementary Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008277634027dcc784f8bc3001f50e37
https://doi.org/10.1158/0008-5472.22425708.v1
https://doi.org/10.1158/0008-5472.22425708.v1
Autor:
Chandrasekhar Kanduri, Tanmoy Mondal, John Inge Johnsen, Matthias Fischer, Per Kogner, Maite Huarte, Leo Kurian, Ivan Raimondi, Santhilal Subhash, Daniel Jachimowicz, Silke Reischl, Subazini Thankaswamy Kosalai, Prasanna Kumar Juvvuna, Mirco Di Marco, Somsundar Veppil Muralidharan, Sanhita Mitra
Primers used in the current investigation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2ea58a04ecaff9b536f62513ff6d74
https://doi.org/10.1158/0008-5472.22425702.v1
https://doi.org/10.1158/0008-5472.22425702.v1
Autor:
Chandrasekhar Kanduri, Tanmoy Mondal, John Inge Johnsen, Matthias Fischer, Per Kogner, Maite Huarte, Leo Kurian, Ivan Raimondi, Santhilal Subhash, Daniel Jachimowicz, Silke Reischl, Subazini Thankaswamy Kosalai, Prasanna Kumar Juvvuna, Mirco Di Marco, Somsundar Veppil Muralidharan, Sanhita Mitra
Neuroblastoma has a low mutation rate for the p53 gene. Alternative ways of p53 inactivation have been proposed in neuroblastoma, such as abnormal cytoplasmic accumulation of wild-type p53. However, mechanisms leading to p53 inactivation via cytoplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23078e939f7b0d29d05e56d567d1d7b8
https://doi.org/10.1158/0008-5472.c.6512115
https://doi.org/10.1158/0008-5472.c.6512115
Autor:
Angela Relógio, Philippe Thomas, Paula Medina-Pérez, Silke Reischl, Sander Bervoets, Ewa Gloc, Pamela Riemer, Shila Mang-Fatehi, Bert Maier, Reinhold Schäfer, Ulf Leser, Hanspeter Herzel, Achim Kramer, Christine Sers
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004338 (2014)
Circadian rhythms are essential to the temporal regulation of molecular processes in living systems and as such to life itself. Deregulation of these rhythms leads to failures in biological processes and eventually to the manifestation of pathologica
Externí odkaz:
https://doaj.org/article/73de2d3c60184e77953fd7619c1d35e2
Autor:
Silke Reischl, Mirco Di Marco, Catarina Darnfors, Kankadeb Mishra, Mohamad Moustafa Ali, Sagar Mahale, Chandrasekhar Kanduri, Meena Kanduri, Subazini Thankaswamy Kosalai, Luisa Statello, Daniel Jachimowicz
Publikováno v:
Oncogene. 40(13)
Recent advances in genomics unraveled several actionable mutational drivers in lung cancer, leading to promising therapies such as tyrosine kinase inhibitors and immune checkpoint inhibitors. However, the tumors' acquired resistance to the newly-deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae031d873196f276e6f126c5c0571e27
https://pubmed.ncbi.nlm.nih.gov/33674747
https://pubmed.ncbi.nlm.nih.gov/33674747
Autor:
Achim Kramer, Barbara Koller, Hannah van Dijk, Bert Maier, Amin Zehtabian, Astrid Grudziecki, Helge Ewers, Adrián E. Granada, Silke Reischl, Hanspeter Herzel, Christian H. Gabriel, Marta del Olmo
The current model of the mammalian circadian oscillator is predominantly based on data from genetics and biochemistry experiments, while the cell biology of circadian clocks is still in its infancy. Here, we describe a new strategy for the efficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020091449d7065c02a20beb9d4bf28fe
Autor:
Sanhita, Mitra, Somsundar Veppil, Muralidharan, Mirco, Di Marco, Prasanna Kumar, Juvvuna, Subazini Thankaswamy, Kosalai, Silke, Reischl, Daniel, Jachimowicz, Santhilal, Subhash, Ivan, Raimondi, Leo, Kurian, Maite, Huarte, Per, Kogner, Matthias, Fischer, John Inge, Johnsen, Tanmoy, Mondal, Chandrasekhar, Kanduri
Publikováno v:
Cancer research. 81(6)
Neuroblastoma has a low mutation rate for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91a7f81fb74ae81018b31a391a55c5ce
https://pubmed.ncbi.nlm.nih.gov/33372039
https://pubmed.ncbi.nlm.nih.gov/33372039
Autor:
Silke Reischl, Achim Kramer
Publikováno v:
Journal of Biological Rhythms. 30:291-301
In mammals, molecular circadian rhythms are generated by autoregulatory transcriptional-translational feedback loops with PERIOD/CRYPTOCHROME containing complexes inhibiting the transcription of their own genes. Although the major circadian oscillato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5921e16b0a1cdb921c9f2e1aa2c3110
https://doi.org/10.1177/0748730415587407
https://doi.org/10.1177/0748730415587407
Autor:
Roman Klemz, Christian Benda, Achim Kramer, Astrid Grudziecki, Thomas Wallach, Ira Schmalen, J. Rajan Prabu, Eva Wolf, Silke Reischl
Publikováno v:
Cell. 157:1203-1215
SummaryPeriod (PER) proteins are essential components of the mammalian circadian clock. They form complexes with cryptochromes (CRY), which negatively regulate CLOCK/BMAL1-dependent transactivation of clock and clock-controlled genes. To define the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b094d1a9097637b9b232faf1fb39a4c
https://doi.org/10.1016/j.cell.2014.03.057
https://doi.org/10.1016/j.cell.2014.03.057