Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Silke, Kayser"'
Autor:
Jacob C. Hansen, Silke Kayser, Kasper B. Hansen, Stylianos Iliadis, Niels Krogsgaard-Larsen, Lennart Bunch, Darryl S. Pickering, Jed T. Syrenne, Markus Staudt, Piero Temperini, Younes Larsen, Birgitte Nielsen, Feng Yi, Aleksandra Moroz
Publikováno v:
ACS Chemical Neuroscience. 11:674-701
Competitive antagonists for ionotropic glutamate receptors (iGluRs) are highly valuable tool compounds for studying health and disease states in the central nervous system. However, only few subtype selective tool compounds are available and the disc
Autor:
Silke, Kayser, Piero, Temperini, Christian B M, Poulie, Markus, Staudt, Birgitte, Nielsen, Darryl S, Pickering, Lennart, Bunch
Publikováno v:
ACS chemical neuroscience. 11(5)
Discovery of chemical tools for the ionotropic glutamate receptors continues to be a challenging task. Herein we report a diversity-oriented approach to new 2,3
Autor:
Silke, Kayser, Jacob C, Hansen, Markus, Staudt, Aleksandra, Moroz, Younes, Larsen, Piero, Temperini, Feng, Yi, Jed T, Syrenne, Niels, Krogsgaard-Larsen, Stylianos, Iliadis, Birgitte, Nielsen, Kasper B, Hansen, Darryl S, Pickering, Lennart, Bunch
Publikováno v:
ACS Chem Neurosci
Competitive antagonists for ionotropic glutamate receptors (iGluRs) are highly valuable tool compounds for studying health and disease states in the central nervous system. However, only few subtype selective tool compounds are available and the disc
Autor:
Seppo Auriola, Kasper B. Hansen, Mikko Gynther, Yevheniia Ishchenko, Darryl S. Pickering, Birgitte Nielsen, Aleksanteri Petsalo, Younes Larsen, Liwei Han, Jacob C. Hansen, Silke Kayser, Ilaria Proietti Silvestri, Tarja Malm, Lennart Bunch
Publikováno v:
Journal of Medicinal Chemistry. 60:9885-9904
The most common solid tumors show intrinsic multidrug resistance (MDR) or inevitably acquire suchwhen treated with anticancer drugs. In this work, we describe the discovery of a peripherally restricted, potent, competitive NMDA receptor antagonist 1l