Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Silke, Frenz"'
Autor:
Estefanía García-Guerrero, Luis G. Rodríguez-Lobato, Belén Sierro-Martínez, Sophia Danhof, Stephan Bates, Silke Frenz, Larissa Haertle, Ralph Götz, Markus Sauer, Leo Rasche, K. Martin Kortüm, Jose A. Pérez-Simón, Hermann Einsele, Michael Hudecek, Sabrina R. Prommersberger
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
B-cell maturation antigen (BCMA) is the lead antigen for chimeric antigen receptor (CAR) T-cell therapy in multiple myeloma (MM). A challenge is inter- and intra-patient heterogeneity in BCMA expression on MM cells and BCMA downmodulation under thera
Externí odkaz:
https://doaj.org/article/c5afb352d346406386ae305b8e18e44f
Autor:
Estefanía, García-Guerrero, Luis G, Rodríguez-Lobato, Belén, Sierro-Martínez, Sophia, Danhof, Stephan, Bates, Silke, Frenz, Larissa, Haertle, Ralph, Götz, Markus, Sauer, Leo, Rasche, K Martin, Kortüm, Jose A, Pérez-Simón, Hermann, Einsele, Michael, Hudecek, Sabrina R, Prommersberger
Publikováno v:
Haematologica.
B-cell maturation antigen (BCMA) is the lead antigen for CAR T-cell therapy in multiple myeloma (MM). A challenge is inter- and intra-patient heterogeneity in BCMA expression on MM cells and BCMA downmodulation under therapeutic pressure. Accordingly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cff22f1d3748edc0be8916035a068e4
https://pubmed.ncbi.nlm.nih.gov/36047086
https://pubmed.ncbi.nlm.nih.gov/36047086
Autor:
Silke Frenz, Ana Yeguas, Judit Rial Saborido, Simone Thomas, Sabrina Kraus, Almudena Navarro-Bailón, Marius Maucher, Katrin Mestermann, Markus Sauer, Halvard Bonig, Christina Verbruggen, Hardikkumar Jetani, Hermann Einsele, Razieh Monjezi, Michael Hudecek, Marcos González, Maik Luu, Dimitrios Mougiakakos, María Belén Vidriales
Publikováno v:
Blood
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Acute myeloid leukemia (AML) is an attractive entity for the development of chimeric antigen receptor (CAR) T-cell immunotherapy because AML blasts are susceptible to T-cell–mediated elimination. Here, we introduce sialic acid–binding immunoglobu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f106d114c68b766ffc0cb1c4540c2cb
http://hdl.handle.net/10261/262144
http://hdl.handle.net/10261/262144
Autor:
Thomas Nerreter, Hermann Einsele, Silke Frenz, Theodoros Giavridis, Michael Hudecek, Justus Weber, Andreas Mades, Michel Sadelain, Katrin Mestermann, Julian Rydzek
Publikováno v:
Science translational medicine. 11(499)
Immunotherapy with chimeric antigen receptor (CAR)-engineered T cells can be effective against advanced malignancies. CAR T cells are "living drugs" that require technologies to enable physicians (and patients) to maintain control over the infused ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716376c047e67fb042e1a8281dbf96bb
https://pubmed.ncbi.nlm.nih.gov/31371792
https://pubmed.ncbi.nlm.nih.gov/31371792
Autor:
Agmal Scherzad, Robert Mlynski, Christine Völker, Rudolf Hagen, Silke Frenz, Kristen Rak, Philipp Schendzielorz, J Völker, Andreas Radeloff, Sibylle Jablonka, Lukas Jürgens
Publikováno v:
Brain Research. 1616:58-70
The cochlear nucleus is the first brainstem nucleus to receive sensory input from the cochlea. Depriving this nucleus of auditory input leads to cellular and molecular disorganization which may potentially be counteracted by the activation or applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e230145cbdb694ed2c28cd057edf83d3
https://doi.org/10.1016/j.brainres.2015.04.055
https://doi.org/10.1016/j.brainres.2015.04.055
Autor:
Andreas Radeloff, Kristen Rak, Rudolf Hagen, J Völker, Robert Mlynski, Agmal Scherzed, Silke Frenz
Publikováno v:
Experimental Brain Research. 226:393-406
Neuronal stem cells have been described in the post-natal cochlear nucleus recently. The aim of the study was to analyse the neurogenic potential in the cochlear nucleus from the early post-natal days until adulthood. Cochlear nuclei from Sprague-Daw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efc054095adf877098680711a980640
https://doi.org/10.1007/s00221-013-3448-x
https://doi.org/10.1007/s00221-013-3448-x
Autor:
Silke Frenz, Lars Wallstabe, Andreas Mades, Hermann Einsele, Christoph Rader, Michael Hudecek
Publikováno v:
Advances in Cell and Gene Therapy. 1:e11
OBJECTIVE: Integrins are heterodimeric receptors that convey cell-to-cell and cell-to-matrix interactions. Integrin α(v)β(3) is expressed in several tumour entities including melanoma, glioblastoma, breast, pancreatic and prostate cancer, where it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb25b93456aed8c5adcf3b229e368f2
https://doi.org/10.1002/acg2.11
https://doi.org/10.1002/acg2.11
Autor:
Rudolf Hagen, Agmal Scherzad, Andreas Radeloff, Kristen Rak, Philipp Schendzielorz, Stefan Hansen, Lukas Jürgens, Sibylle Jablonka, J Völker, Silke Frenz, Robert Mlynski
The Brn3.1 gene encodes for the protein Brn3.1, which is a member of the POU-IV class of transcription factors. Mutation leads to nonsyndromic human progressive hearing loss (DFNA15). To investigate the suitability of the Brn3.1 promoter for Cre reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2843d511e7e2899456d412fa558199
https://www.ncbi.nlm.nih.gov/pubmed/25714426
https://www.ncbi.nlm.nih.gov/pubmed/25714426
Autor:
J Völker, Sibylle Jablonka, Robert Mlynski, Silke Frenz, Andreas Radeloff, Rudolf Hagen, Philipp Schendzielorz, Kristen Rak, Agmal Scherzad
Publikováno v:
Neuroreport. 25(12)
The cochlear nucleus is the first relay station for acoustic information in the auditory pathway and its cellular integrity is affected by hearing loss. Neurotrophic factors, which are known to regulate fundamental processes in the brain, are express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c5b833f7f3a5aa059017b14ee3b909
https://pubmed.ncbi.nlm.nih.gov/24978398
https://pubmed.ncbi.nlm.nih.gov/24978398
Autor:
Janos Groh, Andreas Radeloff, Rudolf Hagen, Robert Mlynski, Kristen Rak, Silke Frenz, Rudolf Martini, Sibylle Jablonka
Publikováno v:
Experimental neurology. 250
The progressive motor neuronopathy (pmn/pmn) mouse, an animal model for a fast developing human motor neuron disorder, is additionally characterized by simultaneous progressive sensorineural hearing loss. The gene defect in the pmn/pmn mouse is local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a5ef57b788ca26d6cbee3a9b347549
https://pubmed.ncbi.nlm.nih.gov/24120439
https://pubmed.ncbi.nlm.nih.gov/24120439