Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Silke, Brüderlein"'
Autor:
Daniela Jäger, Thomas F. E. Barth, Silke Brüderlein, Angelika Scheuerle, Beate Rinner, Adrian von Witzleben, André Lechel, Patrick Meyer, Regine Mayer-Steinacker, Alexandra von Baer, Markus Schultheiss, Christian R. Wirtz, Peter Möller, Kevin Mellert
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Chordomas are rare tumours of the bone arising along the spine from clivus to sacrum. We compared three chordoma cell lines of the clivus region including the newly established clivus chordoma cell line, U-CH14, with nine chordoma cell lines
Externí odkaz:
https://doaj.org/article/0d1eed0325ea49689979e4d5afd31ace
Autor:
Michael J. Böhm, Ralf Marienfeld, Daniela Jäger, Kevin Mellert, Adrian von Witzleben, Silke Brüderlein, Mathias Wittau, Alexandra von Baer, Markus Schultheiss, Regine Mayer-Steinacker, Frank G. Rücker, Peter Möller, Lars Bullinger, Thomas F. E. Barth
Publikováno v:
Sarcoma, Vol 2019 (2019)
Leiomyosarcoma (LMS) is characterized by high genomic complexity, and to date, no specific targeted therapy is available. In a genome-wide approach, we profiled genomic aberrations in a small cohort of eight primary tumours, two relapses, and eight m
Externí odkaz:
https://doaj.org/article/8b49dfb082ed4a899ba3d82ba9ca5faa
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Overview ideogram of CGH data of all chordoma cell lines. Every cell line corresponds to one color. Lines on the left side are losses, and on the right side are gains of chromosomal material. Arrows mark the CDK6 region on 7q and p16 region on 9p.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22432424b3589aded01b88cbefae001b
https://doi.org/10.1158/0008-5472.22405980
https://doi.org/10.1158/0008-5472.22405980
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Detailed CGH karyograms of the chordoma cell lines as shown in the ideogram in Supplementary Figure 1 (according to ISCN: International System for Human Cytogentic Nomenclature).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfb5a546a6fe306ace804d42f52d913
https://doi.org/10.1158/0008-5472.22405947.v1
https://doi.org/10.1158/0008-5472.22405947.v1
Autor:
Frank Leithäuser, Peter Möller, Olga Ritz, Karola Dorsch, Thomas F. Barth, Silke Brüderlein, Beate Wotschke, Gerhard Moldenhauer, Sergey W. Popov
Activation-induced cytidine deaminase (AID) initiates somatic hypermutation (SHM) and class switch recombination (CSR) in activated B lymphocytes and is potentially implicated in genomic instability of B-cell malignancies. For unknown reasons, B-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9757f84fd1c0a19404982308b8b51d2a
https://doi.org/10.1158/0008-5472.c.6494784.v1
https://doi.org/10.1158/0008-5472.c.6494784.v1
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Results of the single tandem repeats analysis of the cell lines U-CH1, U-CH2, UCH3, UCH6, UCH7, U-CH10, U-CH11 and UCH12. The results of the sex typing marker AMEL and the detected alleles for the markers D3S1358, D1S1656, D2S441, D10S1248, D13S317,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69c2c151f2d7436e431e5661051d346
https://doi.org/10.1158/0008-5472.22405935
https://doi.org/10.1158/0008-5472.22405935
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Expression data of mRNA as shown by box plot graphs for brachyury (A), collagen 2A1 (B) and CD24 (C).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d76d51bc136c951cf4eb24b0a813b34
https://doi.org/10.1158/0008-5472.22405968
https://doi.org/10.1158/0008-5472.22405968
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Unsupervised cluster analysis of mRNA expression data of all chordoma cell lines. The T-gene (i.e., brachyury) is overexpressed (red). Cluster Analysis of chordoma cell lines with chondrocyte, liposarcoma and sarcoma expression data from GEO and own
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001350286941634aa2d4c28074da49ef
https://doi.org/10.1158/0008-5472.22405965
https://doi.org/10.1158/0008-5472.22405965
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Effect of Abemaciclib (LY2835219) on the growth of chordoma lines U-CH1, U-CH6, CAL51 (negative control), and MCF7 (positive control). Cells were grown in 96-well-plates were incubated for 3 days at 37{degree sign}C with increasing concentrations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da51fa6256d47d79bab1ebc007066fa1
https://doi.org/10.1158/0008-5472.22405953.v1
https://doi.org/10.1158/0008-5472.22405953.v1
Autor:
Thomas F.E. Barth, Silke Brüderlein, Peter Möller, Adrienne M. Flanagan, Markus Schultheiss, Alexandra von Baer, Regine Mayer-Steinacker, Marko Kornmann, Michael Böhm, Kevin Mellert, André Lechel, Holger Barth, Ralf Marienfeld, Lukas T. Goerttler, Adrian von Witzleben
Western blot analyses of 8 chordoma cell lines showing expression of brachyury at 47 kDa.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218778bf53706d7326e13063b4d28807
https://doi.org/10.1158/0008-5472.22405974
https://doi.org/10.1158/0008-5472.22405974