Výsledky vyhledávání - "Silja Raschke"

Akademický článek

Adipo-Myokines: Two Sides of the Same Coin—Mediators of Inflammation and Mediators of Exercise

Publikováno v: Mediators of Inflammation, Vol 2013 (2013)

This review summarizes the current literature regarding the most discussed contraction-regulated moykines like IL-6, IL-15, irisin, BDNF, ANGPTL4, FGF21, myonectin and MCP-1. It is suggested that the term myokine is restricted to proteins secreted fr

Externí odkaz: https://doaj.org/article/5f94d146fe99463bbb3d479357cd8af8

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Akademický článek

Identification and validation of novel contraction-regulated myokines released from primary human skeletal muscle cells.

Autor: Silja Raschke, Kristin Eckardt, Kirsten Bjørklund Holven, Jørgen Jensen, Jürgen Eckel

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e62008 (2013)

Proteins secreted by skeletal muscle, so called myokines, have been shown to affect muscle physiology and additionally exert systemic effects on other tissues and organs. Although recent profiling studies have identified numerous myokines, the amount

Externí odkaz: https://doaj.org/article/d063d6aaa64f458191a434ef72d577de

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Akademický článek

Evidence against a beneficial effect of irisin in humans.

Autor: Silja Raschke, Manuela Elsen, Hans Gassenhuber, Mark Sommerfeld, Uwe Schwahn, Barbara Brockmann, Raphael Jung, Ulrik Wisløff, Arnt E Tjønna, Truls Raastad, Jostein Hallén, Frode Norheim, Christian A Drevon, Tania Romacho, Kristin Eckardt, Juergen Eckel

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e73680 (2013)

Brown adipose tissue has gained interest as a potential target to treat obesity and metabolic diseases. Irisin is a newly identified hormone secreted from skeletal muscle enhancing browning of white fat cells, which improves systemic metabolism by in

Externí odkaz: https://doaj.org/article/4e438abf22d641678b904f6d3ad82f55

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Impact of hyperinsulinemia and hyperglycemia on valvular interstitial cells – A link between aortic heart valve degeneration and type 2 diabetes

Autor: G. Hege Thoresen, Jens W. Fischer, Jessica I. Selig, Mareike Barth, Payam Akhyari, Silja Raschke, Artur Lichtenberg, D. Margriet Ouwens

Type 2 diabetes is a known risk factor for cardiovascular diseases and is associated with an increased risk to develop aortic heart valve degeneration. Nevertheless, molecular mechanisms leading to the pathogenesis of valve degeneration in the contex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4133ada7b44bc05df8f9c8e7450c208e
http://hdl.handle.net/10852/74226

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Degenerative aortic valve disease and diabetes: Implications for a link between proteoglycans and diabetic disorders in the aortic valve

Autor: Payam Akhyari, Silja Raschke, Artur Lichtenberg, Svenja Klose, Jessica I. Selig, Antje Schomakers, Mareike Barth, Udo Boeken, Lena S. Kiene, Jens W. Fischer

Publikováno v: Diabetesvascular disease research. 16(3)

Degenerative aortic valve disease in combination with diabetes is an increasing burden worldwide. There is growing evidence that particularly small leucine-rich proteoglycans are involved in the development of degenerative aortic valve disease. Never

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3a82a089b159d2900c383ad5980583
https://pubmed.ncbi.nlm.nih.gov/30563371

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