Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Silja Andradottir"'
Autor:
Sarah Warsi, Ulrika Blank, Maria Dahl, Tan Hooi Min Grahn, Ludwig Schmiderer, Silja Andradottir, Stefan Karlsson
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
Life-long production of blood from hematopoietic stem cells (HSCs) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like self-renewal - a cardinal feature of HSCs. Bone morphogenetic proteins (BMP) have an establ
Externí odkaz:
https://doaj.org/article/37bbd038d752424c8e2625681ba76262
Autor:
Sarah, Warsi, Ulrika, Blank, Maria, Dahl, Tan, Hooi Min Grahn, Ludwig, Schmiderer, Silja, Andradottir, Stefan, Karlsson
Publikováno v:
Haematologica
Life-long production of blood from hematopoietic stem cells (HSCs) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like self-renewal - a cardinal feature of HSCs. Bone morphogenetic proteins (BMP) have an establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c34b27f84e5896797672e29ea7786263
https://pubmed.ncbi.nlm.nih.gov/32675226
https://pubmed.ncbi.nlm.nih.gov/32675226
Autor:
Mats Ehinger, Emma Rörby, Stefan Karlsson, Maria Dahl, Ulrika Blank, Matilda Billing, Silja Andradottir
Publikováno v:
Experimental hematology. 55
Transforming growth factor-β (TGFβ) is a member of a large family of polypeptide growth factors. TGFβ signals mainly through the intracellular proteins Smad2 and Smad3, which are highly similar in amino acid sequence identity. A number of studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885c6a266f2576a076e7e53e28764864
https://pubmed.ncbi.nlm.nih.gov/28666967
https://pubmed.ncbi.nlm.nih.gov/28666967
The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells
Autor:
Stefan Karlsson, Maria Dahl, Jan-Ingvar Jönsson, Silja Andradottir, Göran Karlsson, Kenichi Miharada, Emma Rörby, Matilda Billing, Ulrika Blank, Kavitha Siva, Sarah Warsi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Pigment epithelium derived factor (PEDF), a ubiquitously expressed 50 kDa secreted glycoprotein, was recently discovered to regulate self-renewal of neural stem cells and have a supportive effect on human embryonic stem cell growth. Here, we analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ea07459381b2cac968e11cc8e8a850
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-140960
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-140960
Autor:
Ronan Quere, Karin Olsson, Roman A. Zubarev, Jörg Cammenga, Mattias Magnusson, Ann C.M. Brun, Stefan Karlsson, Silja Andradottir, Göran Karlsson
Publikováno v:
Leukemia
Abstract 3154 Multiple genetic hits are detected in patients with acute myeloid leukemia (AML). To investigate this further, we developed a tetracycline inducible mouse model of AML, where the initial transforming event, overexpression of HOXA10, can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1260aa306d86fba57f1081c3cbef1c7
https://doi.org/10.1038/leu.2010.281
https://doi.org/10.1038/leu.2010.281
Publikováno v:
Experimental Hematology. 44:S107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44df986e69960bd59671a331a5f3f784
https://doi.org/10.1016/j.exphem.2016.06.239
https://doi.org/10.1016/j.exphem.2016.06.239
Autor:
Emma Rörby, Kavitha Siva, Stefan Karlsson, Kenichi Miharada, Maria Dahl, Ulrika Blank, Simon Hultmark, Matilda Billing, Silja Andradottir, Göran Karlsson, Mattias Magnusson
Publikováno v:
Experimental Hematology. 42:S57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d9cc2ca88d71ef02d5533d5a448fffa
https://doi.org/10.1016/j.exphem.2014.07.216
https://doi.org/10.1016/j.exphem.2014.07.216
Publikováno v:
Blood. 120:1194-1194
Abstract 1194 The Bone Morphogenetic Proteins (BMPs), which belong to the TGF-beta superfamily of ligands, figure prominently during development and are involved in a wide variety of biological processes throughout life. BMP ligands signal via Type I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f5e114e206c241d929bb3873409ebe
https://doi.org/10.1182/blood.v120.21.1194.1194
https://doi.org/10.1182/blood.v120.21.1194.1194
Autor:
Magnus K. Magnusson, Silja Andradottir
Publikováno v:
Blood. 106:3509-3509
Constitutively activated fusion tyrosine kinases of the Platelet-dervied growth factor β receptor (PDGFβR) family have been described in patients with chronic myelomonocytic leukemia (CMML). Like other tyrosine kinase driven myeloproliferative synd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cb18342643c77a8ed6d221a84cb0775
https://doi.org/10.1182/blood.v106.11.3509.3509
https://doi.org/10.1182/blood.v106.11.3509.3509
Autor:
Jörg Cammenga, Ronan Quere, Stefan Karlsson, Karin Olsson, Kristian Reckzeh, Silja Andradottir, Göran Karlsson, Falk Hertwig, Marianne Rissler
Publikováno v:
University of Copenhagen
Hematopoietic stem cells (HSC) are subject to complex regulation by many signal transduction pathways and transcription factors. In leukemia, these regulatory circuits are abnormal and generate dysregulated growth of HSC and their progeny. Among the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc8ce071547f9adccd2075435a67483
https://curis.ku.dk/portal/en/publications/smad4-as-a-therapeutic-target-in-nup98hoxa9induced-leukemia(c26c20ed-455a-4889-8e42-8a4ece5c63d4).html
https://curis.ku.dk/portal/en/publications/smad4-as-a-therapeutic-target-in-nup98hoxa9induced-leukemia(c26c20ed-455a-4889-8e42-8a4ece5c63d4).html