Geographic EBV variants confound disease-specific variant interpretation and predict variable immune therapy responses.

Autor: Briercheck EL; Division of Hematology and Oncology, University of Washington, Seattle, WA.; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA., Ravishankar S; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA.; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA., Ahmed EH; Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH., Carías Alvarado CC; Laboratorio de Investigación Biológica en Cáncer, Liga Nacional Contra el Cáncer & Instituto de Cancerología, Guatemala City, Guatemala., Barrios Menéndez JC; Laboratorio de Investigación Biológica en Cáncer, Liga Nacional Contra el Cáncer & Instituto de Cancerología, Guatemala City, Guatemala., Silva O; Department of Pathology, Stanford University School of Medicine, Stanford, CA.; Stanford University School of Medicine, Stanford, CA., Solórzano-Ortiz E; Laboratorio de Investigación Biológica en Cáncer, Liga Nacional Contra el Cáncer & Instituto de Cancerología, Guatemala City, Guatemala., Siliézar Tala MM; Laboratorio de Investigación Biológica en Cáncer, Liga Nacional Contra el Cáncer & Instituto de Cancerología, Guatemala City, Guatemala., Stevenson P; Division of Clinical Biostatistics, Fred Hutchinson Cancer Center, Seattle, WA., Xu Y; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA.; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA., Wohns AW; Stanford University School of Medicine, Stanford, CA., Enriquez-Vera D; Department of Pathology, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru., Barrionuevo C; Department of Pathology, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru., Yu SC; Department of Pathology at National Taiwan University Hospital, Taipei, Taiwan., Freud AG; Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH.; Department of Pathology Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH., Oakes C; Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH.; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH., Weigel C; Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH.; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH., Weinstock DM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Klimaszewski HL; College of Medicine, The Ohio State University, Columbus, OH., Ngankeu A; Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH., Mutalima N; Epidemiology and Genetics Unit, Department of Health Sciences, University of York, York, United Kingdom., Samayoa-Reyes G; Department of Immunology and Microbiology, University of Colorado, Anschutz Medical Campus, Aurora, CO., Newton R; Epidemiology and Genetics Unit, Department of Health Sciences, University of York, York, United Kingdom., Rochford R; Department of Immunology and Microbiology, University of Colorado, Anschutz Medical Campus, Aurora, CO., Valvert F; Laboratorio de Investigación Biológica en Cáncer, Liga Nacional Contra el Cáncer & Instituto de Cancerología, Guatemala City, Guatemala., Natkunam Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA.; Stanford University School of Medicine, Stanford, CA., Shustov A; Division of Hematology and Oncology, University of Washington, Seattle, WA.; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA., Baiocchi RA; Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH.; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH., Warren EH; Division of Hematology and Oncology, University of Washington, Seattle, WA.; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA.; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA.

Publikováno v: Blood advances [Blood Adv] 2024 Jul 23; Vol. 8 (14), pp. 3731-3744.