Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Silas Pinto"'
Autor:
Carlos A. Vergani-Junior, Raíssa De P. Moro, Silas Pinto, Evandro A. De-Souza, Henrique Camara, Deisi L. Braga, Guilherme Tonon-da-Silva, Thiago L. Knittel, Gabriel P. Ruiz, Raissa G. Ludwig, Katlin B. Massirer, William B. Mair, Marcelo A. Mori
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cellular response to redox imbalance is crucial for organismal health. microRNAs are implicated in stress responses. ALG-1, the C. elegans ortholog of human AGO2, plays an essential role in microRNA processing and function. Here we investiga
Externí odkaz:
https://doaj.org/article/3b0b37fbeb1a4553a647cd8257d8d1b5
Autor:
Silas Pinto, Vitor N. Sato, Evandro A. De-Souza, Rafael C. Ferraz, Henrique Camara, Ana Paula F. Pinca, Diego R. Mazzotti, Michael T. Lovci, Guilherme Tonon, Camila M. Lopes-Ramos, Raphael B. Parmigiani, Martin Wurtele, Katlin B. Massirer, Marcelo A. Mori
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 84-92 (2018)
Alterations in microRNA (miRNA) processing have been previously linked to aging. Here we used the small molecule enoxacin to pharmacologically interfere with miRNA biogenesis and study how it affects aging in C. elegans. Enoxacin extended worm lifesp
Externí odkaz:
https://doaj.org/article/e2472728753c41be9c28092b2a0a0932
Autor:
Henrique Camara, Carlos A. Vergani-Junior, Silas Pinto, Thiago L. Knittel, Willian G. Salgueiro, Guilherme Tonon-da-Silva, Juliana Ramirez, Evandro A. De-Souza, Marcelo A. Mori
Intertissue RNA transport has emerged as a novel signaling mechanism. InC. elegans, this is conferred by the systemic RNAi pathway, in which the limiting step is the cellular import of extracellular RNAs via SID-1. To better understand the physiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65de0abafa621a5c9d308ad5aac60d97
https://doi.org/10.1101/2022.11.23.517635
https://doi.org/10.1101/2022.11.23.517635
Caenorhabditis eleganswith impaired insulin/IGF-1 receptor signalling (IIS) or with germline ablation live longer and this phenomenon is entirely dependent on the transcription factor DAF-16 - theC. eleganshomolog of the class O of the forkhead box t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb185f3680f9236ec154b2048659fd7
https://doi.org/10.1101/2022.10.21.513151
https://doi.org/10.1101/2022.10.21.513151
Autor:
Ferrucci, Danilo1, Silva, Silas Pinto2, Rocha, Andr2,3, Nascimento, Lucas1, Vieira, André Schwambach1, Taboga, Sebastião Roberto4, Mori, Marcelo2,3, Lenz-Cesar, Carlos5,6, Carvalho, Hernandes F.1,6 hern@unicamp.br
Publikováno v:
Scientific Reports. 12/17/2019, Vol. 9 Issue 1, p1-15. 15p.
Autor:
Silas Pinto, Bruna B. Brandão, Søren Nørvang Madsen, Jørn Wulff Helge, Jessica L. O. Branquinho, Marcelo A. Mori, Beatriz Alves Guerra, Sara G. Vienberg, Steen Larsen, Jan-Wilhelm Kornfeld, Ditte Søgaard, Daniela S. Razolli, Matteo Oliverio, Atefeh Rabiee, C. Ronald Kahn, Danilo Lopes Ferrucci, Thomas Nielsen, Gabriel Palermo Ruiz, William T. Festuccia, Juleen R. Zierath, Thiago L. Knittel, Adriano S. Martins, Brice Emanuelli, Jonas T. Treebak, Josef Brandauer, Licio A. Velloso
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Brandão, B B, Madsen, S, Rabiee, A, Oliverio, M, Ruiz, G P, Ferrucci, D L, Branquinho, J L, Razolli, D, Pinto, S, Nielsen, T S, Festuccia, W T, Martins, A S, Guerra, B A, Knittel, T L, Søgaard, D, Larsen, S, Helge, J W, Brandauer, J, Velloso, L A, Emanuelli, B, Kornfeld, J W, Kahn, C R, Vienberg, S G, Zierath, J R, Treebak, J T & Mori, M A 2020, ' Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 38, pp. 23932-23941 . https://doi.org/10.1073/pnas.2011243117
Proc Natl Acad Sci U S A
Universidade de São Paulo (USP)
instacron:USP
Brandão, B B, Madsen, S, Rabiee, A, Oliverio, M, Ruiz, G P, Ferrucci, D L, Branquinho, J L, Razolli, D, Pinto, S, Nielsen, T S, Festuccia, W T, Martins, A S, Guerra, B A, Knittel, T L, Søgaard, D, Larsen, S, Helge, J W, Brandauer, J, Velloso, L A, Emanuelli, B, Kornfeld, J W, Kahn, C R, Vienberg, S G, Zierath, J R, Treebak, J T & Mori, M A 2020, ' Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 38, pp. 23932-23941 . https://doi.org/10.1073/pnas.2011243117
Proc Natl Acad Sci U S A
DICER is a key enzyme in microRNA (miRNA) biogenesis. Here we show that aerobic exercise training up-regulates DICER in adipose tissue of mice and humans. This can be mimicked by infusion of serum from exercised mice into sedentary mice and depends o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503d7036ed09be07ad12f921a505d0ac
https://doi.org/10.1073/pnas.2011243117
https://doi.org/10.1073/pnas.2011243117
Autor:
Claudio A. Masuda, Silas Pinto, Antonio Galina, Henrique Camara, Ana Luiza F. V. De-Queiroz, Caio M. Machado, Marcelo A. Mori, Mikaella L. Felix-Formiga, Felipe S. A. Pimentel, Evandro A. De-Souza, Mónica Montero-Lomelí
Publikováno v:
J Biol Chem
In the presence of galactose, lithium ions activate the unfolded protein response (UPR) by inhibiting phosphoglucomutase activity and causing the accumulation of galactose-related metabolites, including galactose-1-phosphate. These metabolites also a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c76e9bba63242f42c098006e521fce8
https://europepmc.org/articles/PMC7086034/
https://europepmc.org/articles/PMC7086034/
Autor:
Vitor Sato, Guilherme Tonon, Camila M. Lopes-Ramos, Ana Paula F. Pinca, Katlin B. Massirer, Rafael Ferraz, Henrique Camara, Evandro A. De-Souza, Silas Pinto, Raphael B. Parmigiani, Marcelo A. Mori, Michael T. Lovci, Diego R. Mazzotti, Martin Würtele
Publikováno v:
Redox Biology, Vol 18, Iss, Pp 84-92 (2018)
Redox Biology
Redox Biology
Alterations in microRNA (miRNA) processing have been previously linked to aging. Here we used the small molecule enoxacin to pharmacologically interfere with miRNA biogenesis and study how it affects aging in C. elegans. Enoxacin extended worm lifesp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109c9cc524d736d83c498d685deb1ab6
http://www.sciencedirect.com/science/article/pii/S2213231718304646
http://www.sciencedirect.com/science/article/pii/S2213231718304646
Autor:
Lucas F. Nascimento, Andr Rocha, Hernandes F. Carvalho, Sebastião Roberto Taboga, Silas Pinto Silva, Carlos Lenz-Cesar, Marcelo A. Mori, André Schwambach Vieira, Danilo Lopes Ferrucci
Publikováno v:
Scientific Reports
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Made available in DSpace on 2020-12-11T05:11:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-17 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8030bc55e70d9bef270f159d6515f632
http://europepmc.org/articles/PMC6917739
http://europepmc.org/articles/PMC6917739
Autor:
Katlin B. Massirer, Ana Paula F. Pinca, Thiago L. Knittel, Raissa P. Moro, Guilherme Tonon, Evandro A. De-Souza, Silas Pinto, Adam Antebi, Amy E. Pasquinelli, Henrique Camara, Marcelo A. Mori, Willian G. Salgueiro
Publikováno v:
Nucleic Acids Research
Nucleic Acids Res
Nucleic Acids Res
RNA interference (RNAi) is a valuable technique to determine gene function. In Caenorhabditis elegans, RNAi can be achieved by feeding worms bacteria carrying a plasmid expressing double-stranded RNA (dsRNA) targeting a gene of interest. The most com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4289a70cbabd6c7d30755c570409fa9
https://pubmed.ncbi.nlm.nih.gov/30838421
https://pubmed.ncbi.nlm.nih.gov/30838421