Výsledky vyhledávání - "Sila Yanardag"

Akademický článek

Prominin 1 is crucial for the early development of photoreceptor outer segments

Autor: Sila Yanardag, Scott Rhodes, Thamaraiselvi Saravanan, Tongju Guan, Visvanathan Ramamurthy

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Abstract Prominin 1 (PROM1) is a pentaspan transmembrane glycoprotein localized on the nascent photoreceptor discs. Mutations in PROM1 are linked to various retinal diseases. In this study, we assessed the role of PROM1 in photoreceptor biology and p

Externí odkaz: https://doaj.org/article/8279a39f068b49c4bea5da400431c024

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Akademický článek

Primary Cilium Is Involved in Stem Cell Differentiation and Renewal through the Regulation of Multiple Signaling Pathways

Autor: Sila Yanardag, Elena N. Pugacheva

Publikováno v: Cells, Vol 10, Iss 6, p 1428 (2021)

Signaling networks guide stem cells during their lineage specification and terminal differentiation. Primary cilium, an antenna-like protrusion, directly or indirectly plays a significant role in this guidance. All stem cells characterized so far hav

Externí odkaz: https://doaj.org/article/11f47c7c6cef4e1e98fec0a9ae98c944

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Nuclear Aurora-A kinase-induced hypoxia signaling drives early dissemination and metastasis in breast cancer: implications for detection of metastatic tumors

Autor: Marc L Purazo, Jasleen Gandhi, Matthew B. Smolkin, Naira V. Margaryan, Sijin Wen, Sila Yanardag, Dongquan Chen, Kristina M Whately, Juergen Loskutov, Elena N. Pugacheva, Maria A. Voronkova, Abha Maskey, Gangqing Hu, Hyeran Choi

Publikováno v: Oncogene

Metastatic breast cancer causes most breast cancer-associated deaths, especially in triple negative breast cancers (TNBC). The metastatic drivers of TNBCs are still poorly understood, and effective treatment non-existent. Here we reveal that the pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13518c1b1747b9f2b021b132fe7773e
https://europepmc.org/articles/PMC9511212/

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Functional Characterization of the Pseudomonas aeruginosa Ribosome Hibernation-Promoting Factor

Autor: Kerry S. Williamson, Michael J. Franklin, Sila Yanardag, Elizabeth L. Sandvik

Publikováno v: J Bacteriol

Hibernation-promoting factor (HPF) is a ribosomal accessory protein that inactivates ribosomes during bacterial starvation. In Pseudomonas aeruginosa, HPF protects ribosome integrity while the cells are dormant. The sequence of HPF has diverged among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5294660dd5ab3d65c04e99c4c29bfa9f
https://pubmed.ncbi.nlm.nih.gov/32900865

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