Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sila Ultanir"'
Autor:
Jianzhi Jiang, Brent Wilkinson, Ilse Flores, Nicolas Hartel, Simeon R. Mihaylov, Veronica A. Clementel, Helen R. Flynn, Fowsan S. Alkuraya, Sila Ultanir, Nicholas A. Graham, Marcelo P. Coba
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
A large number of synaptic proteins have been recurrently associated with complex brain disorders. One of these proteins, the Traf and Nck interacting kinase (TNIK), is a postsynaptic density (PSD) signaling hub, with many variants reported in neurod
Externí odkaz:
https://doaj.org/article/71c2f47483de4fde9adf3e8577e72175
Autor:
Anna Laddach, Song Hui Chng, Reena Lasrado, Fränze Progatzky, Michael Shapiro, Alek Erickson, Marisol Sampedro Castaneda, Artem V. Artemov, Ana Carina Bon-Frauches, Eleni-Maria Amaniti, Jens Kleinjung, Stefan Boeing, Sila Ultanir, Igor Adameyko, Vassilis Pachnis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Glial cells have been proposed as a source of neural progenitors, but the mechanisms underpinning the neurogenic potential of adult glia are not known. Using single cell transcriptomic profiling, we show that enteric glial cells represent a
Externí odkaz:
https://doaj.org/article/86392e391ca64dc18dbed188143dce59
Autor:
Roman O Fedoryshchak, Magdalena Přechová, Abbey M Butler, Rebecca Lee, Nicola O'Reilly, Helen R Flynn, Ambrosius P Snijders, Noreen Eder, Sila Ultanir, Stephane Mouilleron, Richard Treisman
Publikováno v:
eLife, Vol 9 (2020)
PPP-family phosphatases such as PP1 have little intrinsic specificity. Cofactors can target PP1 to substrates or subcellular locations, but it remains unclear how they might confer sequence-specificity on PP1. The cytoskeletal regulator Phactr1 is a
Externí odkaz:
https://doaj.org/article/d44fd2f8800b402e9a011331fbee17e9
Autor:
Vassilis Pachnis, Anna Laddach, Song Hui Chng, Reena Lasrado, Franze Progatzky, Michael Shapiro, Alek Erickson, Marisol Sampedro-Castaneda, Artem Artemov, Ana Carina Bon-Frauches, Jens Kleinjung, Stefan Boeing, Sila Ultanir, Igor Adameyko, Eleni-Maria Amaniti
Development of the nervous system is underpinned by changes in gene expression and chromatin configuration during embryogenesis and early postnatal life. To uncover the molecular mechanisms orchestrating cell lineage differentiation and maturation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d0596ea135acb1470c0c5693777e91
https://doi.org/10.21203/rs.3.rs-2491905/v1
https://doi.org/10.21203/rs.3.rs-2491905/v1
Autor:
Marisol Sampedro-Castañeda, Lucas L. Baltussen, Andre T. Lopes, Yichen Qiu, Liina Sirvio, Simeon R. Mihaylov, Suzanne Claxton, Jill C. Richardson, Gabriele Lignani, Sila Ultanir
Developmental and epileptic encephalopathies (DEEs) are a group of rare childhood disorders characterized by severe epilepsy and cognitive deficits. Numerous DEE genes have been discovered thanks to advances in genomic diagnosis, yet putative molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08c61c39b38c41f4ebdf1447fb6375a3
https://doi.org/10.1101/2022.11.24.517538
https://doi.org/10.1101/2022.11.24.517538
Autor:
Anna Laddach, Song Hui Chng, Reena Lasrado, Fränze Progatzky, Michael Shapiro, Artem Artemov, Marisol Sampedro Castaneda, Alek Erickson, Ana Carina Bon-Frauches, Jens Kleinjung, Stefan Boeing, Sila Ultanir, Igor Adameyko, Vassilis Pachnis
How neurogenesis and gliogenesis are coordinated during development and why mature glial cells often share properties with neuroectodermal progenitors remains unclear. Here, we have used single cell RNA sequencing to map the regulatory landscape of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f8ff5358f57a8c136b18f2b2c689f0f
https://doi.org/10.1101/2022.07.12.499640
https://doi.org/10.1101/2022.07.12.499640
Autor:
Paolo La Montanara, Arnau Hervera, Lucas Baltussen, Thomas Hutson, Ilaria Palmisano, Francesco De Virgiliis, Yunan Gao, Qasim A. Majid, Nikos Gorgoraptis, Kingsley Wong, Jenny Downs, Vincenzo Di Lazzaro, Tommaso Pizzorusso, Sila Ultanir, Helen Leonard, Nagy Istvan, Nicholas D Mazarakis, Simone Di Giovanni
Cyclin-dependent-like kinase 5 (Cdkl5) gene mutations lead to an X-linked disorder that is characterized by infantile epileptic encephalopathy, developmental delay and hypotonia. However, we found that a substantial percentage of these patients also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03823b6c4ca6f61a6ab20e88b17a9bcd
https://doi.org/10.1101/690172
https://doi.org/10.1101/690172