Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sikta Pradhan"'
Publikováno v:
The Journal of Clinical Pharmacology. 37:635-648
Polymorphisms and other genetic factors related to enzymes metabolizing drugs and xenobiotic chemicals are well known. This article focuses on selected molecular mechanisms and introduces some of the clinical implications arising from genetically det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b50d2a9940f41ae4f167d17192b7992
https://doi.org/10.1002/j.1552-4604.1997.tb04347.x
https://doi.org/10.1002/j.1552-4604.1997.tb04347.x
Publikováno v:
International Journal of Pharmaceutics. 138:207-213
The kinetics of methazolamide (MTZ) in human whole blood, red blood cells (RBCs) and plasma have been investigated. The study was conducted over a wide dose range using three single-dose (25, 50 or 100 mg) and two multiple-dose (50 mg q 12 h × 3 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9549eba2c35ef0630fe79d43c7c6aaf
https://doi.org/10.1016/0378-5173(96)04536-x
https://doi.org/10.1016/0378-5173(96)04536-x
Publikováno v:
Biochemical Pharmacology. 30:1071-1076
Changes in levels of substance P-like immunoreactivity (SPLI) were observed in the rat dorsal raphe nucleus after cocaine treatment and were compared with concurrent cocaine-induced changes in 5-hydroxytryptamine (5-HT) content in the pons-medulla (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addf9073a3537a008d23f570bfc80499
https://doi.org/10.1016/0006-2952(81)90444-5
https://doi.org/10.1016/0006-2952(81)90444-5
Publikováno v:
Neuropharmacology. 20:541-548
Striatonigral substance P pathways have been postulated to be the excitatory component of a feedback loop which assists in modulating the activity of the nigrostriatal dopaminergic system. Data presented in this paper supports this hypothesis by demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2caf5478b96cb43ae3f87948c0b2e4
https://doi.org/10.1016/0028-3908(81)90206-9
https://doi.org/10.1016/0028-3908(81)90206-9
Publikováno v:
Drug Development Research. 12:287-296
Different liquid diets were tested as vehicles for ethanol administration in order to maximize the blood ethanol level (BEL) in rats. This was done since maternal BEL during the gestation period is believed to be the determining factor for behavioral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf6f4335fa9262afe1211e253e3a209
https://doi.org/10.1002/ddr.430120312
https://doi.org/10.1002/ddr.430120312
Publikováno v:
Neuropharmacology. 20(2)
The dependence on pH of rat striatal tyrosine hydroxylase (TH) was studied both in the presence and absence of phosphorylating conditions. In the absence of phosphorylating conditions the K m of TH for the cofactor 6MPH 4 increased with increasing pH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636a0533f2addb05930f278064f47158
https://pubmed.ncbi.nlm.nih.gov/6111042
https://pubmed.ncbi.nlm.nih.gov/6111042
Publikováno v:
Neuropharmacology. 20(12A)
The effect of cocaine on the binding of specific radioligands to rat striatal dopamine (DA) receptors and on the activation by DA of striatal adenylate cyclase activity was studied in vivo and in vitro. As early as 60 min after an injection of cocain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be401ef2860fc98f73810e69262ca70
https://pubmed.ncbi.nlm.nih.gov/7322289
https://pubmed.ncbi.nlm.nih.gov/7322289
Publikováno v:
In Marihuana Biological Effects: Analysis, Metabolism, Cellular Responses, Reproduction and Brain 1979:567-583