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Disruption of histone methylation in developing sperm impairs offspring health transgenerationally

Autor: Siklenka, Keith, Erkek, Serap, Godmann, Maren, Lambrot, Romain, McGraw, Serge, Lafleur, Christine, Cohen, Tamara, Xia, Jianguo, Suderman, Matthew, Hallett, Michael, Trasler, Jacquetta, Peters, Antoine H. F. M., Kimmins, Sarah

Publikováno v: Science, 2015 Nov 01. 350(6261), 651-651.

Externí odkaz: http://www.jstor.org/stable/24740791

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Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function.

Autor: McCutcheon SR; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA., Swartz AM; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA., Brown MC; Department of Neurosurgery, Duke University School of Medicine, Durham, NC 27710, USA., Barrera A; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA.; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27710, USA., Amador CM; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA.; Department of Pharmacology and Cancer Biology, Durham, NC 27710, USA., Siklenka K; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA.; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27710, USA., Humayun L; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA., Isaacs JM; Duke Cancer Institute Center for Cancer Immunotherapy, Duke University School of Medicine, Durham, NC 27710, USA., Reddy TE; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA.; Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27710, USA., Nair S; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.; Duke Cancer Institute Center for Cancer Immunotherapy, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA., Antonia S; Duke Cancer Institute Center for Cancer Immunotherapy, Duke University School of Medicine, Durham, NC 27710, USA., Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.; Center for Advanced Genomic Technologies, Duke University, Durham, NC 27708, USA.; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 01. Date of Electronic Publication: 2023 May 01.