Genetic Landscape of Patients With Dilated Cardiomyopathy and a Systemic Immune-Mediated Disease.

Autor: Stroeks SLVM; Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht University, Maastricht, the Netherlands; Cardiovascular Sciences, KU Leuven, Leuven, Belgium; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., Henkens MTHM; Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht University, Maastricht, the Netherlands; Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands; Netherlands Heart Institute (NLHI), Utrecht, the Netherlands., Dominguez F; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Madrid Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, Madrid, Spain; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Merlo M; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, University of Trieste, Italy., Hellebrekers DMEI; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., Gonzalez-Lopez E; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Madrid Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, Madrid, Spain; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Dal Ferro M; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, University of Trieste, Italy., Ochoa JP; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Madrid Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, Madrid, Spain; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Venturelli F; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, University of Trieste, Italy., Claes GRF; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., Venner MFGHM; Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht University, Maastricht, the Netherlands., Krapels IPC; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., Vanhoutte EK; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands., van Paassen P; Department of Nephrology and Clinical Immunology, Maastricht University Medical Center, Maastricht, the Netherlands., van den Wijngaard A; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Netherlands Heart Institute (NLHI), Utrecht, the Netherlands., Sikking MA; Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht University, Maastricht, the Netherlands., van Leeuwen R; Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht University, Maastricht, the Netherlands., Abdul Hamid M; Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands., Li X; Department of Pathology, Maastricht University Medical Centre, Maastricht, the Netherlands., Brunner HG; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Human Genetics, Radboud University Medical Center, Nijmegen, Netherlands., Sinagra G; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, University of Trieste, Italy., Garcia-Pavia P; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Madrid Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, CIBERCV, Madrid, Spain; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Heymans SRB; Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht University, Maastricht, the Netherlands; Cardiovascular Sciences, KU Leuven, Leuven, Belgium., Verdonschot JAJ; Cardiovascular Research Institute Maastricht, Department of Cardiology, Maastricht University, Maastricht, the Netherlands; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart (ERN GUARD-Heart), Amsterdam, the Netherlands; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands. Electronic address: job.verdonschot@mumc.nl.

Publikováno v: JACC. Heart failure [JACC Heart Fail] 2024 Oct 05. Date of Electronic Publication: 2024 Oct 05.

Papillary Muscle Delayed Hyperenhancement: Prevalence and Clinical Implications in a Large Population With Dilated Cardiomyopathy.

Autor: Beijnink CWH; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., Raafs AG; Department of Cardiology, Cardiovascular Research Institute (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., Vos JL; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., Verdonschot JAJ; Department of Cardiology, Cardiovascular Research Institute (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., Sikking MA; Department of Cardiology, Cardiovascular Research Institute (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands., Rodwell L; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., Heymans SRB; Department of Cardiology, Cardiovascular Research Institute (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands.; Department of Cardiovascular Research, University of Leuven, Leuven, Belgium., Nijveldt R; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands.

Publikováno v: JACC. Advances [JACC Adv] 2024 Jul 13; Vol. 3 (8), pp. 101103. Date of Electronic Publication: 2024 Jul 13 (Print Publication: 2024).

Clonal Hematopoiesis of Indeterminate Potential From a Heart Failure Specialist's Point of View.

Autor: Sikking MA; Department of Cardiology Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center (MUMC) Maastricht the Netherlands., Stroeks SLVM; Department of Cardiology Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center (MUMC) Maastricht the Netherlands., Waring OJ; Department of Pathology Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center (MUMC) Maastricht the Netherlands., Henkens MTHM; Department of Pathology Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center (MUMC) Maastricht the Netherlands.; Netherlands Heart Institute (NLHI) Utrecht the Netherlands., Riksen NP; Department of Internal Medicine Radboud University Medical Center Nijmegen the Netherlands., Hoischen A; Department of Human Genetics Radboud University Medical Center Nijmegen the Netherlands., Heymans SRB; Department of Cardiology Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center (MUMC) Maastricht the Netherlands.; Department of Cardiovascular Research University of Leuven Belgium., Verdonschot JAJ; Department of Cardiology Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Center (MUMC) Maastricht the Netherlands.; Department of Clinical Genetics Maastricht University Medical Center (MUMC) Maastricht the Netherlands.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2023 Aug; Vol. 12 (15), pp. e030603. Date of Electronic Publication: 2023 Jul 25.

Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy.

Autor: Sikking MA; Department of Cardiology, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht (CARIM), 6229 HX Maastricht, The Netherlands., Stroeks SLVM; Department of Cardiology, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht (CARIM), 6229 HX Maastricht, The Netherlands., Henkens MTHM; Department of Pathology, Maastricht University Medical Centre, 6229 HX Maastricht, The Netherlands.; Netherlands Heart Institute (NLHI), 3511 EP Utrecht, The Netherlands., Venner MFGHM; Department of Cardiology, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht (CARIM), 6229 HX Maastricht, The Netherlands., Li X; Department of Pathology, Maastricht University Medical Centre, 6229 HX Maastricht, The Netherlands., Heymans SRB; Department of Cardiology, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht (CARIM), 6229 HX Maastricht, The Netherlands.; Centre for Molecular and Vascular Biology, Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, 3000 Leuven, Belgium., Hazebroek MR; Department of Cardiology, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht (CARIM), 6229 HX Maastricht, The Netherlands., Verdonschot JAJ; Department of Cardiology, Maastricht University Medical Centre, Cardiovascular Research Institute Maastricht (CARIM), 6229 HX Maastricht, The Netherlands.; Department of Clinical Genetics, Maastricht University Medical Centre, 6229 HX Maastricht, The Netherlands.

Publikováno v: Journal of clinical medicine [J Clin Med] 2023 Jun 09; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 09.

Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy.

Autor: Stroeks SLVM; Cardiovascular Research Institute Maastricht (CARIM); S.L.V.M.S., T.H.M.H., A.G.R., M.A.S., E.A.V.J., S.R.B.H., J.A.J.V.), Maastricht University, Maastricht, Netherlands.; KU Leuven, Cardiovascular Sciences, Belgium (S.L.V.M.S., E.A.V.J., S.R.B.H.)., Lunde IG; Genetics, Harvard Medical School, Boston, MA (I.G.L., H.W., J.G.).; Diagnostics and Technology, Akershus University Hospital, Oslo, Norway (I.G.L.)., Hellebrekers DMEI; Clinical Genetics, Maastricht University Medical Center, the Netherlands (D.M.E.I.H., G.R.F.C., I.P.C.K., E.P.K., A.v.d.W., H.G.B., J.A.J.V.)., Claes GRF; Clinical Genetics, Maastricht University Medical Center, the Netherlands (D.M.E.I.H., G.R.F.C., I.P.C.K., E.P.K., A.v.d.W., H.G.B., J.A.J.V.)., Wakimoto H; Genetics, Harvard Medical School, Boston, MA (I.G.L., H.W., J.G.)., Gorham J; Genetics, Harvard Medical School, Boston, MA (I.G.L., H.W., J.G.)., Krapels IPC; Clinical Genetics, Maastricht University Medical Center, the Netherlands (D.M.E.I.H., G.R.F.C., I.P.C.K., E.P.K., A.v.d.W., H.G.B., J.A.J.V.)., Vanhoutte EK, van den Wijngaard A; Clinical Genetics, Maastricht University Medical Center, the Netherlands (D.M.E.I.H., G.R.F.C., I.P.C.K., E.P.K., A.v.d.W., H.G.B., J.A.J.V.)., Henkens MTHM, Raafs AG; Cardiovascular Research Institute Maastricht (CARIM); S.L.V.M.S., T.H.M.H., A.G.R., M.A.S., E.A.V.J., S.R.B.H., J.A.J.V.), Maastricht University, Maastricht, Netherlands., Sikking MA; Cardiovascular Research Institute Maastricht (CARIM); S.L.V.M.S., T.H.M.H., A.G.R., M.A.S., E.A.V.J., S.R.B.H., J.A.J.V.), Maastricht University, Maastricht, Netherlands., Broers JLV; Genetics and Cell Biology (J.L.V.B., M.N.), Maastricht University, Maastricht, Netherlands., Nabben M; Genetics and Cell Biology (J.L.V.B., M.N.), Maastricht University, Maastricht, Netherlands., Jones EAV; Cardiovascular Research Institute Maastricht (CARIM); S.L.V.M.S., T.H.M.H., A.G.R., M.A.S., E.A.V.J., S.R.B.H., J.A.J.V.), Maastricht University, Maastricht, Netherlands.; KU Leuven, Cardiovascular Sciences, Belgium (S.L.V.M.S., E.A.V.J., S.R.B.H.)., Heymans SRB; KU Leuven, Cardiovascular Sciences, Belgium (S.L.V.M.S., E.A.V.J., S.R.B.H.)., Brunner HG; Clinical Genetics, Maastricht University Medical Center, the Netherlands (D.M.E.I.H., G.R.F.C., I.P.C.K., E.P.K., A.v.d.W., H.G.B., J.A.J.V.).; Radboud University Medical Center, Human Genetics, Nijmegen, the Netherlands (H.G.B.)., Verdonschot JAJ; Cardiovascular Research Institute Maastricht (CARIM); S.L.V.M.S., T.H.M.H., A.G.R., M.A.S., E.A.V.J., S.R.B.H., J.A.J.V.), Maastricht University, Maastricht, Netherlands.; Clinical Genetics, Maastricht University Medical Center, the Netherlands (D.M.E.I.H., G.R.F.C., I.P.C.K., E.P.K., A.v.d.W., H.G.B., J.A.J.V.).

Publikováno v: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2023 Apr; Vol. 16 (2), pp. e003788. Date of Electronic Publication: 2023 Mar 27.