Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sikha Rauth"'
Publikováno v:
Oncogene. 22:4911-4917
Malignant melanomas are frequently characterized by elevated levels of wild-type p53, suggesting that p53 function could be suppressed by a mechanism different from p53 mutation. We analysed the functionality of the p53-signaling pathway in a panel o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfc9f339b0e4cab9c471da7691143d3
https://doi.org/10.1038/sj.onc.1206741
https://doi.org/10.1038/sj.onc.1206741
Publikováno v:
British Journal of Cancer
We have investigated the effect of the soybean isoflavone genistein on the growth and differentiation of human melanoma cells. Four human melanoma cell lines, either completely lacking or containing different levels of wild-type p53, were treated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a51fcbf97aa9f20d874a8aad60fdd8c
http://europepmc.org/articles/PMC2223540
http://europepmc.org/articles/PMC2223540
Publikováno v:
Pigment Cell Research. 9:85-91
Tyrosinase, the key gene in melanin pigment synthesis, is tissue-specifically expressed in melanocytic cells. Expression of this gene is regulated by various hormones, carcinogens, and environmental factors. The molecular basis underlying tyrosinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65c221b5035677313d634feccea7c82
https://doi.org/10.1111/j.1600-0749.1996.tb00094.x
https://doi.org/10.1111/j.1600-0749.1996.tb00094.x
Publikováno v:
Surgical Oncology Clinics of North America. 3:563-577
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e6a572ad2302dd05e99541fe638e1dd
https://doi.org/10.1016/s1055-3207(18)30502-7
https://doi.org/10.1016/s1055-3207(18)30502-7
Autor:
Sikha Rauth, Richard L. Davidson
Publikováno v:
Somatic Cell and Molecular Genetics. 19:285-293
5-Bromodeoxyuridine (BrdU), a thymidine analog, suppresses melanogenesis in Syrian hamster melanoma cells. Tyrosinase, which is the key enzyme for the synthesis of melanin, is suppressed by exposure to BrdU, and the drop in enzyme activity is correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8912a074d93c685684669fe106cd2b
https://doi.org/10.1007/bf01233076
https://doi.org/10.1007/bf01233076
Publikováno v:
Somatic Cell and Molecular Genetics. 16:129-141
The murine adenosine deaminase (ADA) gene has a GC-rich promoter that is structurally typical of many mammalian "housekeeping" gene promoters. The ability of the ADA gene promoter to support diverse tissue-specific gene expression was investigated. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7cd6bd8b9c8248cb52647c137c6d0b
https://doi.org/10.1007/bf01233043
https://doi.org/10.1007/bf01233043
Publikováno v:
British Journal of Cancer
Metastatic melanoma, compared with other cancers, appears to be unusual because of its low frequency of p53 mutations and prevalence of wild-type p53 protein in advanced malignancy. Here, we examined the effects of wild-type and mutated p53 (143 Val-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a208ed70aebf609827983337aa83b1d7
https://pubmed.ncbi.nlm.nih.gov/9649136
https://pubmed.ncbi.nlm.nih.gov/9649136
Publikováno v:
In vitro cellulardevelopmental biology. Animal. (2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc5c1922d7583a8a3b44f70d79bf7ed
https://pubmed.ncbi.nlm.nih.gov/8012659
https://pubmed.ncbi.nlm.nih.gov/8012659
Bromodeoxyuridine- and cyclic AMP-mediated regulation of tyrosinase in Syrian hamster melanoma cells
Publikováno v:
Somatic cell and molecular genetics. 16(6)
The thymidine analog 5-bromodeoxyuridine (BrdU) suppresses pigmentation and tyrosinase activity in Syrian hamster melanoma cells W1-1-1. Studies on the molecular mechanism of suppression of pigmentation indicated that BrdU treatment affects the level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304a431c85510a22cfa8dca69027e2c2
https://pubmed.ncbi.nlm.nih.gov/2176354
https://pubmed.ncbi.nlm.nih.gov/2176354
Publikováno v:
Melanoma Research. 7:S97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::793cf6ef1716fd5d960bb66339af80dd
https://doi.org/10.1097/00008390-199706001-00338
https://doi.org/10.1097/00008390-199706001-00338