Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sik Y. Ho"'
Autor:
Mingxi Weng, Sik Y. Ho, Xiaoxiao Yang, Yanpu Chen, Derek Hoi Hang Ho, Ralf Jauch, Jian Yan, Hans R. Schöler, Johannes Graumann, Gary D. Stormo, Yogesh Srivastava, Anastasia Bednarz, Ya Gao, Yuanjie Wei, Sergiy Velychko, Thomas Braun, Daisylyn Senna Tan, Johnny Kim, Vikas Malik, Ligang Fan
Publikováno v:
Molecular Biology and Evolution
Transcription factor-driven cell fate engineering in pluripotency induction, transdifferentiation, and forward reprogramming requires efficiency, speed, and maturity for widespread adoption and clinical translation. Here, we used Oct4, Sox2, Klf4, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a59703c3bb3cce02eb205c63ea6683d
https://doi.org/10.1093/molbev/msab075
https://doi.org/10.1093/molbev/msab075
Autor:
Jane Park, Srinivasaraghavan Kannan, Eneda Toska, Maurizio Scaltriti, Charles L. Sawyers, Emiliano Cocco, Ralf Jauch, Wouter R. Karthaus, Dara S. Ross, Daisylyn Senna Tan, Yanyan Cai, Fan Wu, Erik Ladewig, Mirna Sallaku, Matthew Witkin, José Baselga, Jesper L.V. Maag, Jorge S. Reis-Filho, Sik Y. Ho, Chandra S. Verma, Srushti Kittane, Barbara Acevedo, Amaia Arruabarrena-Aristorena, Lorenzo Ferrando, Richard Koche, Pier Selenica, Pedram Razavi
Publikováno v:
Cancer Cell
Mutations in the pioneer transcription factor FOXA1 are a hallmark of estrogen receptor-positive (ER(+)) breast cancers. Examining FOXA1 in ~5,000 breast cancer patients identifies several hotspot mutations in the Wing2 region and a breast cancer-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a301bfbe753d5649c1f16465194a84e2
https://doi.org/10.1016/j.ccell.2020.08.003
https://doi.org/10.1016/j.ccell.2020.08.003
Autor:
Jane Park, Charles L. Sawyers, Emiliano Cocco, Pedram Razavi, Jorge S. Reis-Fihlo, Pier Selenica, Daisylyn Senna Tan, Srinivasaraghavan Kannan, Eneda Toska, Wouter R. Karthaus, Ralf Jauch, Amaia Arruabarrena-Aristorena, Jesper L.V. Maag, José Baselga, Maurizio Scaltriti, Yanyan Cai, Mirna Sallaku, Chandra S. Verma, Richard Koche, Lorenzo Ferrando, Srushti Kittane, Sik Y. Ho
Publikováno v:
Cancer Research. 80:3439-3439
FOXA1 is an evolutionary conserved pioneer factor that binds to condensed chromatin allowing the recruitment of other transcription factors to the DNA. Although mutations in FOXA1 are a hallmark of estrogen receptor-positive (ER+) breast cancers, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6896ae8ac0de9507f8702b2f58ffe353
https://doi.org/10.1158/1538-7445.am2020-3439
https://doi.org/10.1158/1538-7445.am2020-3439