Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection study

Autor: Koopman, Jan Pieter R., Houlder, Emma L., Janse, Jacqueline J., Casacuberta-Partal, Miriam, Lamers, Olivia A.C., Sijtsma, Jeroen C., de Dood, Claudia, Hilt, Stan T., Ozir-Fazalalikhan, Arifa, Kuiper, Vincent P., Roozen, Geert V.T., de Bes-Roeleveld, Laura M., Kruize, Yvonne C.M., Wammes, Linda J., Smits, Hermelijn H., van Lieshout, Lisette, van Dam, Govert J., van Amerongen-Westra, Inge M., Meij, Pauline, Corstjens, Paul L.A.M., Jochems, Simon P., van Diepen, Angela, Yazdanbakhsh, Maria, Hokke, Cornelis H., Roestenberg, Meta

Publikováno v: In eBioMedicine November 2023 97

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Ageing of Plasmodium falciparum malaria sporozoites alters their motility, infectivity and reduces immune activation in vitro.

Autor: van Schuijlenburg, Roos, Azargoshasb, Samaneh, de Korne, Clarize M., Sijtsma, Jeroen C., Bezemer, Sascha, van der Ham, Alwin J., Baalbergen, Els, Geurten, Fiona, de Bes‑Roeleveld, Laura M., Chevalley‑Maurel, Severine C., van Oosterom, Matthias N., van Leeuwen, Fijs W. B., Franke‑Fayard, Blandine, Roestenberg, Meta

Publikováno v: Malaria Journal; 4/19/2024, Vol. 23, p1-14, 14p, 1 Color Photograph, 6 Graphs

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Protective efficacy of short-term infection with Necator americanus hookworm larvae in healthy volunteers in the Netherlands: a single-centre, placebo-controlled, randomised, controlled, phase 1 trial.

Autor: Hoogerwerf MA; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Janse JJ; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Kuiper VP; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., van Schuijlenburg R; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Kruize YC; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Sijtsma JC; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Nosoh BA; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Koopman JR; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Verbeek-Menken PH; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Westra IM; Leiden University Center for Infectious Diseases, and Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, Netherlands., Meij P; Leiden University Center for Infectious Diseases, and Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, Netherlands., Brienen EA; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Visser LG; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., van Lieshout L; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Jochems SP; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Yazdanbakhsh M; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands., Roestenberg M; Department of Parasitology, Leiden University Medical Center, Leiden, Netherlands; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands. Electronic address: m.roestenberg@lumc.nl.

Publikováno v: The Lancet. Microbe [Lancet Microbe] 2023 Dec; Vol. 4 (12), pp. e1024-e1034.