Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sijia Yi"'
Development of process analytical tools for rapid monitoring of live virus vaccines in manufacturing
Autor:
Sijia Yi, Reilly McCracken, Joseph Davide, Daniel Ryan Salovich, Travis Whitmer, Aditya Bhat, Josef Vlasak, Sha Ha, Darrell Sehlin, Joseph Califano, Kristin Ploeger, Malini Mukherjee
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract In the development of end-to-end large-scale live virus vaccine (LVV) manufacturing, process analytical technology (PAT) tools enable timely monitoring of critical process parameters (CPP) and significantly guide process development and char
Externí odkaz:
https://doaj.org/article/e6e04a053d5a4be59f82f4a832c5d1ea
Autor:
Sijia Yi, Sun-Young Kim, Michael P. Vincent, Simseok A. Yuk, Sharan Bobbala, Fanfan Du, Evan Alexander Scott
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104555- (2022)
Summary: Plasmid DNA (pDNA) transfection is advantageous for gene therapies requiring larger genetic elements, including “all-in-one” CRISPR/Cas9 plasmids, but is limited by toxicity as well as poor intracellular release and transfection efficien
Externí odkaz:
https://doaj.org/article/d432c22450994663a654c2b64e717126
Autor:
Fanfan Du, Baofu Qiao, Trung Dac Nguyen, Michael P. Vincent, Sharan Bobbala, Sijia Yi, Chamille Lescott, Vinayak P. Dravid, Monica Olvera de la Cruz, Evan Alexander Scott
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Natural biomolecules such as peptides and DNA can dynamically self-organize into diverse hierarchical structures. Here the authors report experiments and simulations on the dynamic network self-assembly and subsequent collapse of the synthetic homopo
Externí odkaz:
https://doaj.org/article/64ac7fd9f98a4752983d43cca3a4d5d0
Autor:
Reilly McCracken, Noor Al-Nazal, Travis Whitmer, Sijia Yi, James M. Wagner, Colin G. Hebert, Matthew J. Lowry, Peter R. Hayes, James W. Schneider, Todd M. Przybycien, Malini Mukherjee
Publikováno v:
Vaccines, Vol 10, Iss 10, p 1589 (2022)
Vaccinations to prevent infectious diseases are given to target the body’s innate and adaptive immune systems. In most cases, the potency of a live virus vaccine (LVV) is the most critical measurement of efficacy, though in some cases the quantity
Externí odkaz:
https://doaj.org/article/c1cb80f7b8c141b6a031515fb76fa7f2
Autor:
Xiaomo Li, Sijia Yi, Débora B. Scariot, Santiago J. Martinez, Ben A. Falk, Cheryl L. Olson, Patricia S. Romano, Evan A. Scott, David M. Engman
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
Chagas disease is caused by infection with the protozoan parasite Trypanosoma cruzi (T. cruzi), an intracellular pathogen that causes significant morbidity and death among millions in the Americas from Canada to Argentina. Current therapy involves or
Externí odkaz:
https://doaj.org/article/740abbba4d284f08b4c84c047dc55ccd
Autor:
Sijia Yi, Nicholas B. Karabin, Jennifer Zhu, Sharan Bobbala, Huijue Lyu, Sophia Li, Yugang Liu, Molly Frey, Michael Vincent, Evan A. Scott
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Chronic unresolved vascular inflammation is a critical factor in the development of atherosclerosis. Cardiovascular immunotherapy has therefore become a recent focus for treatment, with the objective to develop approaches that can suppress excessive
Externí odkaz:
https://doaj.org/article/3082ebaf7bad4308a990d1e3d5862a30
Autor:
Rajini Nagaraj, Trevor Stack, Sijia Yi, Benjamin Mathew, Kenneth R Shull, Evan A Scott, Mathew T Mathew, Divya Rani Bijukumar
Publikováno v:
Nanomaterials, Vol 10, Iss 3, p 581 (2020)
Diabetic retinopathy (DR), Retinopathy of Pre-maturity (ROP), and Age-related Macular Degeneration (AMD) are multifactorial manifestations associated with abnormal growth of blood vessels in the retina. These three diseases account for 5% of the tota
Externí odkaz:
https://doaj.org/article/c80011e2c3054c4bb69ed930cef0b4ee
Publikováno v:
2022 IEEE International Conference on Networking, Sensing and Control (ICNSC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3aeb149be23483ee3fb22540895fb0d
https://doi.org/10.1109/icnsc55942.2022.10004131
https://doi.org/10.1109/icnsc55942.2022.10004131
Publikováno v:
2022 IEEE International Conference on Networking, Sensing and Control (ICNSC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b662be02e0c7b0f4b9ca882432dd43c
https://doi.org/10.1109/icnsc55942.2022.10004099
https://doi.org/10.1109/icnsc55942.2022.10004099
Publikováno v:
2022 IEEE International Conference on Networking, Sensing and Control (ICNSC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82f1a0cca51cfe30df2425bbc4e1a60
https://doi.org/10.1109/icnsc55942.2022.10004193
https://doi.org/10.1109/icnsc55942.2022.10004193