Výsledky vyhledávání - "Siiri, Reinikka"

Akademický článek

Whole-exome sequencing reveals candidate high-risk susceptibility genes for endometriosis

Autor: Susanna Nousiainen, Outi Kuismin, Siiri Reinikka, Roosa Manninen, Sara Khamaiseh, Mari Kuivalainen, Anna Terho, Sari Koivurova, Maarit Niinimäki, Kari Salokas, Markku Varjosalo, Anne Ahtikoski, Ralf Bützow, Outi Lindgren, Outi Uimari, Pia Vahteristo

Publikováno v: Human Genomics, Vol 17, Iss 1, Pp 1-10 (2023)

Abstract Background Endometriosis is a common, chronic disease among fertile-aged women. Disease course may be highly invasive, requiring extensive surgery. The etiology of endometriosis remains elusive, though a high level of heritability is well es

Externí odkaz: https://doaj.org/article/6dacf57f4e0f49a8840d6d3a6215fa94

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Akademický článek

A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase

Autor: Miika Mehine, Terhi Ahvenainen, Sara Khamaiseh, Jouni Härkönen, Siiri Reinikka, Tuomas Heikkinen, Anna Äyräväinen, Päivi Pakarinen, Päivi Härkki, Annukka Pasanen, Anna-Liisa Levonen, Ralf Bützow, Pia Vahteristo

Publikováno v: Oncogenesis, Vol 11, Iss 1, Pp 1-10 (2022)

Abstract Uterine leiomyomas, or fibroids, are the most common tumors in women of reproductive age. Uterine leiomyomas can be classified into at least three main molecular subtypes according to mutations affecting MED12, HMGA2, or FH. FH-deficient lei

Externí odkaz: https://doaj.org/article/199d3f3126b54a4fbad0c263ac974ff4

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3′ RNA and whole‐genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2 , HMGA1 , or PLAG1

Autor: Vilja Jokinen, Miika Mehine, Siiri Reinikka, Sara Khamaiseh, Terhi Ahvenainen, Anna Äyräväinen, Päivi Härkki, Ralf Bützow, Annukka Pasanen, Pia Vahteristo

Publikováno v: Genes, Chromosomes and Cancer. 62:27-38

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0d596c13d754b496d2f75eb89d34290
https://doi.org/10.1002/gcc.23088

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3'RNA and whole-genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1

Autor: Vilja, Jokinen, Miika, Mehine, Siiri, Reinikka, Sara, Khamaiseh, Terhi, Ahvenainen, Anna, Äyräväinen, Päivi, Härkki, Ralf, Bützow, Annukka, Pasanen, Pia, Vahteristo

Publikováno v: Genes, chromosomescancerREFERENCES. 62(1)

Uterine leiomyomas, or fibroids, are very common smooth muscle tumors that arise from the myometrium. They can be divided into distinct molecular subtypes. We have previously shown that 3'RNA-sequencing is highly effective in classifying archival for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d9b3f8c305d6ae308b064f2ac1d79306
https://pubmed.ncbi.nlm.nih.gov/35822448

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