Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease

Autor: Edmans, J.G., Ollington, B., Colley, H.E., Santocildes-Romero, M.E., Siim Madsen, L., Hatton, P.V., Spain, S.G., Murdoch, C.

Chronic ulcerative oral mucosal inflammatory diseases, including oral lichen planus and recurrent aphthous stomatitis, are painful and highly prevalent, yet lack effective clinical management. In recent years, systemic biologic therapies, including m

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https://eprints.whiterose.ac.uk/190213/1/1-s2.0-S016836592200520X-main.pdf

Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease.

Autor: Edmans JG; School of Clinical Dentistry, 19 Claremont Crescent, University of Sheffield, Sheffield S10 2TA, UK; Department of Chemistry, Brook Hill, University of Sheffield, Sheffield S3 7HF, UK., Ollington B; School of Clinical Dentistry, 19 Claremont Crescent, University of Sheffield, Sheffield S10 2TA, UK., Colley HE; School of Clinical Dentistry, 19 Claremont Crescent, University of Sheffield, Sheffield S10 2TA, UK. Electronic address: h.colley@sheffield.ac.uk., Santocildes-Romero ME; AFYX Therapeutics, Lergravsej 57, 2. tv, 2300 Copenhagen, Denmark., Siim Madsen L; AFYX Therapeutics, Lergravsej 57, 2. tv, 2300 Copenhagen, Denmark., Hatton PV; School of Clinical Dentistry, 19 Claremont Crescent, University of Sheffield, Sheffield S10 2TA, UK., Spain SG; Department of Chemistry, Brook Hill, University of Sheffield, Sheffield S3 7HF, UK., Murdoch C; School of Clinical Dentistry, 19 Claremont Crescent, University of Sheffield, Sheffield S10 2TA, UK.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2022 Oct; Vol. 350, pp. 146-157. Date of Electronic Publication: 2022 Aug 18.