Výsledky vyhledávání - "Sihem Benaboud"

Akademický článek

Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique—SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d’Anesthésie et Réanimation—SFAR)

Autor: Romain Guilhaumou, Sihem Benaboud, Youssef Bennis, Claire Dahyot-Fizelier, Eric Dailly, Peggy Gandia, Sylvain Goutelle, Sandrine Lefeuvre, Nicolas Mongardon, Claire Roger, Julien Scala-Bertola, Florian Lemaitre, Marc Garnier

Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-20 (2019)

Abstract Background Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the intensive care unit (ICU). ICU patients present many pathophysiological features that cause pharmacokinetic (PK) and pharmacodynamic (PD) specificities,

Externí odkaz: https://doaj.org/article/a95e4bbf19074fbd8efce22c8038c53a

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Oral levofloxacin: population pharmacokinetics model and pharmacodynamics study in bone and joint infections

Autor: Etienne Canouï, Solen Kerneis, Philippe Morand, Maya Enser, Rémy Gauzit, Luc Eyrolle, Philippe Leclerc, Adrien Contejean, Yi Zheng, Philippe Anract, Deborah Hirt, Jean Marc Treluyer, Naim Bouazza, Sihem Benaboud

Publikováno v: Journal of Antimicrobial Chemotherapy. 77:1344-1352

Objectives This study aimed at characterizing the pharmacokinetics (PK) of oral levofloxacin in adult patients in order to optimize dosing scheme and explore the PK/pharmacodynamics (PD) of levofloxacin in bone and joint infections (BJIs). Methods Fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc3dc237fba470608f20987431670fa
https://doi.org/10.1093/jac/dkac031

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Piperacillin Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children Receiving Continuous Renal Replacement Therapy

Autor: Michael Thy, Saïk Urien, Frantz Foissac, Naïm Bouazza, Inès Gana, Emmanuelle Bille, Agathe Béranger, Julie Toubiana, Romain Berthaud, Fabrice Lesage, Sylvain Renolleau, Jean-Marc Tréluyer, Sihem Benaboud, Mehdi Oualha

Publikováno v: Antimicrob Agents Chemother

We aimed to develop a piperacillin population pharmacokinetic (PK) model in critically ill children receiving continuous renal replacement therapy (CRRT) and to optimize dosing regimens. The piperacillin plasma concentration was quantified by high-pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b05b3f22b0f18f5c3aaa72c40b49e12
https://europepmc.org/articles/PMC9764994/

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Meropenem Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children Receiving Continuous Renal Replacement Therapy

Autor: Michael Thy, Saik Urien, Naim Bouazza, Frantz Foissac, Inès Gana, Emmanuelle Bille, Agathe Béranger, Julie Toubiana, Romain Berthaud, Fabrice Lesage, Sylvain Renolleau, Jean-Marc Tréluyer, Sihem Benaboud, Mehdi Oualha

Publikováno v: Clinical pharmacokinetics. 61(11)

We aimed to develop a meropenem population pharmacokinetic model in critically ill children receiving continuous renal replacement therapy and simulate dosing regimens to optimize patient exposure.Meropenem plasma concentration was quantified by high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56061c196acd829b7e6c96b2e3e01176
https://pubmed.ncbi.nlm.nih.gov/36251162

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Population pharmacokinetics of cefazolin in critically ill children infected with methicillin-sensitive Staphylococcus aureus

Autor: Julie Toubiana, Jean-Marc Tréluyer, Sihem Benaboud, E. Bille, Saik Urien, Florence Moulin, Guillaume Geslain, Mehdi Oualha, E. Salvador, Yi Zheng, Inès Gana, C. Briand, Olivier Bustarret, Déborah Hirt, S. Renolleau, S. Boujaafar, Agathe Béranger

Publikováno v: Clinical Microbiology and Infection. 27:413-419

Objectives Cefazolin is one of curative treatments for infections due to methicillin-sensitive Staphylococcus aureus (MSSA). Both growth and critical illness may impact the pharmacokinetic (PK) parameters. We aimed to build a population PK model for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07fe52e84713a846308e58ef7c24f8e
https://doi.org/10.1016/j.cmi.2020.04.022

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Plasma Concentrations and Safety of Lopinavir/Ritonavir in COVID-19 Patients

Autor: Celia Azoulay, Jeremie Zerbit, Solen Kernéis, Laurent Chouchana, Paul Legendre, Rui Batista, Yi Zheng, Sana Boujaafar, Benjamin Terrier, Jean-Marc Treluyer, Lucile Regard, Sihem Benaboud, Nicolas Carlier, Etienne Canouï, Inès Gana, Laure-Hélène Preta

Publikováno v: Therapeutic Drug Monitoring

Background Although the efficacy of lopinavir/ritonavir has not been proven, it has been proposed as an off-label treatment for COVID-19. Previously, it has been reported that the plasma concentrations of lopinavir significantly increase in inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35638027da5cc925ce78e5a9f889283e
https://doi.org/10.1097/ftd.0000000000000838

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Dosing Recommendations for Lamotrigine in Children: Evaluation Based on Previous and New Population Pharmacokinetic Models

Autor: Radia Aboura, Naïm Bouazza, Inès Gana, Jean-Marc Tréluyer, Isabelle Desguerre, Camille Chenevier-Gobeaux, Yi Zheng, Rima Nabbout, Déborah Hirt, Manon Tauzin, Sihem Benaboud, Cécile Freihuber, Thierry Billette de Villemeur

Publikováno v: The Journal of Clinical Pharmacology. 61:677-687

Lamotrigine is a broad-spectrum antiepileptic drug with high interindividual variability in serum concentrations in children. The aims of this study were to evaluate the predictive performance of pediatric population pharmacokinetic (PPK) models publ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4accbe9973611d2b0e640ecda786b5f4
https://doi.org/10.1002/jcph.1791

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