Výsledky vyhledávání - "Sihem, Sassi"

Akademický článek

Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis

Autor: Carol M. Artlett, Sihem Sassi-Gaha, Jennifer L. Hope, Carol A. Feghali-Bostwick, Peter D. Katsikis

Publikováno v: Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-8 (2017)

Abstract Background Despite the important role that microRNAs (miRNAs) play in immunity and inflammation, their involvement in systemic sclerosis (SSc) remains poorly characterized. miRNA-155 (miR-155) plays a role in pulmonary fibrosis and its expre

Externí odkaz: https://doaj.org/article/a8c9561d26774d778d9b845e5945974b

Zobrazit plný text záznamu

Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis

Autor: Sihem Sassi-Gaha, Carol Feghali-Bostwick, Jennifer L. Hope, Peter D. Katsikis, Carol M. Artlett

Publikováno v: Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-8 (2017)
Arthritis Research & Therapy
Arthritis Research & Therapy, 19:144. BioMed Central Ltd.

Background Despite the important role that microRNAs (miRNAs) play in immunity and inflammation, their involvement in systemic sclerosis (SSc) remains poorly characterized. miRNA-155 (miR-155) plays a role in pulmonary fibrosis and its expression can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6c25c90c6c81a7415761129dce4df9
https://hdl.handle.net/1765/100733

Zobrazit plný text záznamu

Modulation at Age of Onset in Tunisian Huntington Disease Patients: Implication of New Modifier Genes

Autor: Saoussen Trabelsi, Imed Harrabi, Sihem Sassi, Dorra H'mida-Ben Brahim, Moez Gribaa, Sana Ben Amor, Marwa Haddaji-Mastouri, Fatma Ezzahra Gahbiche, Ali Saad, Marwa Chourabi, Soumaya Mougou-Zereli, Sofiane Ben Ammou, Turkia Lamouchi

Publikováno v: Genetics Research International, Vol 2014 (2014)
Genetics Research International

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder. The causative mutation is an expansion of more than 36 CAG repeats in the first exon of IT15 gene. Many studies have shown that the IT15 interacts with several modifier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2160449a6b1a772a85da985c186e55
https://doi.org/10.1155/2014/210418

Zobrazit plný text záznamu

Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer

Autor: Carol M. Artlett, Sihem Sassi-Gaha, James D. Thacker, Beth Overley-Adamson, Connie Stephens, Ransome D Weis

Publikováno v: Cancer Biology & Therapy

Increasing health care costs in the US are due in a large part to the increasing prevalence of chronic diseases in an aging population. Current therapeutic strategies for treating chronic diseases alleviate symptoms allowing patients to live longer w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690777854612e1874a3b33ec5a9cc0c6
https://doi.org/10.4161/cbt.27820

Zobrazit plný text záznamu

Partial KCNQ1OT1 hypomethylation: A disguised familial Beckwith–Wiedemann syndrome as a sporadic adrenocortical tumor

Autor: Dorra H'mida Ben-Brahim, Sihem Sassi, Saoussen Trabelsi, Mohamed Neji Guediche, Ali Saad, Abdelfattah Zakhama, Marwa Haddaji Mastouri, Moez Gribaa, Soumaya Mougou, S. Hammami, Maroua Chourabi

Publikováno v: Applied & Translational Genomics
Applied and Translational Genomics, Vol 4, Iss C, Pp 1-3 (2015)

Beckwith–Wiedemann syndrome has a wide spectrum of complications such as embryonal tumors, namely adrenocortical tumor. Tumor predisposition is one of the most challenging manifestations of this syndrome. A 45-day old female with a family history o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af55704547abfc673a99a0284a8852cb

Zobrazit plný text záznamu

Assessment of MYCN amplification status in Tunisian neuroblastoma: CISH and MLPA combining approach

Autor: Dorra, H'Mida Ben Brahim, Saoussen, Trabelsi, Imen, Chabchoub, Inesse, Gargouri, Imed, Harrabi, Adnene, Moussa, Maroua, Chourabi, Marwa, Haddaji, Sihem, Sassi, Soumaya, Mougou, Moez, Gribaa, Slim, Ben Ahmed, Abdelfattah, Zakhama, Abdellatif, Nouri, Ali, Saad

Publikováno v: La Tunisie medicale. 93(8-9)

Neuroblastoma (NB) shows a complex combination of genetic aberrations. Some of them represent poor genetic prognosis factors that require specific and intensive chemotherapy. MYCN amplification consists of the major bad outcome prognostic factor, it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07b11c5e8a48a6d691555cd416d94006
https://pubmed.ncbi.nlm.nih.gov/26815518

Zobrazit plný text záznamu

Rapid sporulation of Bacillus anthracis in a high iron, glucose-free medium

Autor: Mitali Purohit, Sihem Sassi-Gaha, Richard F. Rest

Publikováno v: Journal of Microbiological Methods. 82:282-287

Spores are the infectious form of Bacillus anthracis (BA), causing cutaneous, inhalation and gastrointestinal anthrax. Because of the possible use of BA spores in a bioterrorism attack, there is considerable interest in studying spore biology. In the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0399d220a8983e436c953cf42f2ef8d
https://doi.org/10.1016/j.mimet.2010.07.004

Zobrazit plný text záznamu

Chimeric cells of maternal origin do not appear to be pathogenic in the juvenile idiopathic inflammatory myopathies or muscular dystrophy

Autor: Ronald C. Ramos, Sihem Sassi-Gaha, Carol M. Artlett, Lisa G. Rider, Frederick W. Miller

Publikováno v: Arthritis Research & Therapy

Introduction Microchimeric cells have been studied for over a decade, with conflicting reports on their presence and role in autoimmune and other inflammatory diseases. To determine whether microchimeric cells were pathogenic or mediating tissue repa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c304d9abe712cc49633b098ae590cff
https://pubmed.ncbi.nlm.nih.gov/26338728

Zobrazit plný text záznamu

Two α-dicarbonyls downregulate migration, invasion, and adhesion of liver cancer cells in a p53-dependent manner

Autor: Carol M. Artlett, Lorena Loarca, Sihem Sassi-Gaha

Publikováno v: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 45(11)

Background Hepatocellular carcinoma accounts for more than 600,000 deaths per year due to it being a highly invasive tumor. The α-dicarbonyl, methylglyoxal demonstrates efficacy at reducing tumor burden, however the anti-cancerous activities of 3-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3697dfd6374c7521e7c57e329a1a8417
https://pubmed.ncbi.nlm.nih.gov/24071451

Zobrazit plný text záznamu

NLRP3 inflammasome is a target for development of broad-spectrum anti-infective drugs

Autor: James D. Thacker, Richard F. Rest, Brian J. Balin, Denah M. Appelt, Mitali Purohit, Carol M. Artlett, Sihem Sassi-Gaha

Publikováno v: Antimicrobial agents and chemotherapy. 56(4)

We describe the molecular mode of action and pharmacodynamics of a new molecular entity (NME) that induces the NLRP3 inflammasome-mediated innate immune response. This innate response reduces the pathogen load in an experimentally induced methicillin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb82b4cabe723618b116ffff3575e610
https://pubmed.ncbi.nlm.nih.gov/22290938

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání