Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Sigurdur Y Kristinsson"'
Autor:
Marianna Thordardottir, Ebba K Lindqvist, Sigrun H Lund, Rene Costello, Debra Burton, Laufey Steingrimsdottir, Neha Korde, Sham Mailankody, Gudny Eiriksdottir, Lenore J Launer, Vilmundur Gudnason, Tamara B Harris, Ola Landgren, Johanna E Torfadottir, Sigurdur Y Kristinsson
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206047 (2018)
The etiology of monoclonal gammopathy of undetermined significance (MGUS), the precursor state of multiple myeloma (MM), is mostly unknown and no studies have been conducted on the effect of diet on MGUS or progression from MGUS to MM. We aimed to ex
Externí odkaz:
https://doaj.org/article/84f52ed2b8904f49ae68eb3bbac921fe
Autor:
Molly Went, Laura Duran-Lozano, Gisli H. Halldorsson, Andrea Gunnell, Nerea Ugidos-Damboriena, Philip Law, Ludvig Ekdahl, Amit Sud, Gudmar Thorleifsson, Malte Thodberg, Thorunn Olafsdottir, Antton Lamarca-Arrizabalaga, Caterina Cafaro, Abhishek Niroula, Ram Ajore, Aitzkoa Lopez de Lapuente Portilla, Zain Ali, Maroulio Pertesi, Hartmut Goldschmidt, Lilja Stefansdottir, Sigurdur Y. Kristinsson, Simon N. Stacey, Thorvardur J. Love, Saemundur Rognvaldsson, Roman Hajek, Pavel Vodicka, Ulrika Pettersson-Kymmer, Florentin Späth, Carolina Schinke, Frits Van Rhee, Patrick Sulem, Egil Ferkingstad, Grimur Hjorleifsson Eldjarn, Ulf-Henrik Mellqvist, Ingileif Jonsdottir, Gareth Morgan, Pieter Sonneveld, Anders Waage, Niels Weinhold, Hauke Thomsen, Asta Försti, Markus Hansson, Annette Juul-Vangsted, Unnur Thorsteinsdottir, Kari Hemminki, Martin Kaiser, Thorunn Rafnar, Kari Stefansson, Richard Houlston, Björn Nilsson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 case
Externí odkaz:
https://doaj.org/article/45458eb3feec4e09b1c186e45ec468d5
Autor:
Shahinaz M Gadalla, Ruth M Pfeiffer, Sigurdur Y Kristinsson, Magnus Björkholm, James E Hilbert, Richard T Moxley, Ola Landgren, Mark H Greene
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79851 (2013)
Recent studies show that patients with myotonic dystrophy (DM) have an increased risk of specific malignancies, but estimates of absolute cancer risk accounting for competing events are lacking. Using the Swedish Patient Registry, we identified 1,081
Externí odkaz:
https://doaj.org/article/8f45da638c3e470b912eaf1abc17cd78
Autor:
Evgenia Mikaelsdottir, Gudmar Thorleifsson, Lilja Stefansdottir, Gisli Halldorsson, Jon K. Sigurdsson, Sigrun H. Lund, Vinicius Tragante, Pall Melsted, Solvi Rognvaldsson, Kristjan Norland, Anna Helgadottir, Magnus K. Magnusson, Gunnar B. Ragnarsson, Sigurdur Y. Kristinsson, Sigrun Reykdal, Brynjar Vidarsson, Ingibjorg J. Gudmundsdottir, Isleifur Olafsson, Pall T. Onundarson, Olof Sigurdardottir, Emil L. Sigurdsson, Gerdur Grondal, Arni J. Geirsson, Gudmundur Geirsson, Julius Gudmundsson, Hilma Holm, Saedis Saevarsdottir, Ingileif Jonsdottir, Gudmundur Thorgeirsson, Daniel F. Gudbjartsson, Unnur Thorsteinsdottir, Thorunn Rafnar, Kari Stefansson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Evgenia Mikaelsdottir et al. report a study of variants associated with platelet count among European individuals where they identify 577 associations. They also report a genetic overlap between platelet count and human diseases, including myeloproli
Externí odkaz:
https://doaj.org/article/446745dde7124b9185d8624ab82cb8ce
Autor:
Sigrun Thorsteinsdottir, Sigrun H. Lund, Ebba K. Lindqvist, Marianna Thordardottir, Gunnar Sigurdsson, Rene Costello, Debra Burton, Hlif Steingrimsdottir, Vilmundur Gudnason, Gudny Eiriksdottir, Kristin Siggeirsdottir, Tamara B. Harris, Ola Landgren, Sigurdur Y. Kristinsson
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2790-2798 (2017)
Abstract: Previous studies have shown that individuals with monoclonal gammopathy of undetermined significance (MGUS) have an increased risk of fractures, although the underlying mechanisms remain unknown. Our aim was to analyze bone mineral density
Externí odkaz:
https://doaj.org/article/0043602f7a264e24a2d5820147b9a46b
Autor:
Gudbjörg Jonsdottir, Sigrún H. Lund, Magnus Björkholm, Ingemar Turesson, Malin Hultcrantz, Anna Porwit, Yogesh S. Jethava, Ola Landgren, Sigurdur Y. Kristinsson
Publikováno v:
Blood Advances, Vol 1, Iss 25, Pp 2392-2398 (2017)
Abstract: In the present study, we aimed to evaluate 2 hypotheses. First, we hypothesize that prior malignancy is a proxy for genetic susceptibility that could be a risk factor for subsequent malignancy development in multiple myeloma (MM) patients.
Externí odkaz:
https://doaj.org/article/65a09fa5d9ed4c9283c15badc11b801a
Autor:
Marianna Thordardottir, Ebba K. Lindqvist, Sigrun H. Lund, Rene Costello, Debra Burton, Neha Korde, Sham Mailankody, Gudny Eiriksdottir, Lenore J. Launer, Vilmundur Gudnason, Tamara B. Harris, Ola Landgren, Sigurdur Y. Kristinsson
Publikováno v:
Blood Advances, Vol 1, Iss 24, Pp 2186-2192 (2017)
Abstract: All multiple myeloma (MM) cases are preceded by the premalignant state monoclonal gammopathy of undetermined significance (MGUS). Results from previous studies show a positive association between obesity and MM; however, the association bet
Externí odkaz:
https://doaj.org/article/789cc6088dac4d13aff5af35b666bfa6
Autor:
Sæmundur Rögnvaldsson, Jon Þórir Oskarsson, Sigrun Thorsteinsdottir, Elin Ruth Reed, Gudrun Asta Sigurdardottir, Brynjar Vidarsson, Pall Torfi Onundarson, Margret Sigurdardottir, Bjarni Agnar Agnarsson, Isleifur Olafsson, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Robert Palmason, Fridbjorn Sigurdsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Thor Aspelund, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Ingigerdur S Sverrisdottir, Gudlaug Katrin Hakonardottir, Thorir Einarsson Long, Ragnar Danielsen, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Thorvardur Jon Love, Sigurdur Y Kristinsson
Publikováno v:
Blood. 140:10024-10026
Autor:
Robert Palmason, Oscar Berlanga, Jon Kristinn Sigurdsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Sara Ekberg, Michael Crowther, Marina Levy, Elin Ruth Reed, Jon Þórir Oskarsson, Gudrun Asta Sigurdardottir, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Fridbjorn Sigurdsson, Isleifur Olafsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Thor Aspelund, Gauti Gislason, Andri Olafsson, Ingigerdur Solveig Sverrisdottir, Hlif Steingrimsdottir, Thorir Einarsson Long, Malin Hultcrantz, Ola Landgren, Stephen Harding, Brian G.M. Durie, Thorvardur Jon Love, Sigurdur Y Kristinsson
Publikováno v:
Blood. 140:2338-2340
Autor:
Robert Palmason, Elias Eythorsson, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Sara Ekberg, Michael Crowther, Elin Ruth Reed, Jon Þórir Oskarsson, Gudrun Asta Sigurdardottir, Thor Aspelund, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Asbjorn Jonsson, Olafur Skuli Indridason, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Hlif Steingrimsdottir, Thorir Einarsson Long, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Runolfur Palsson, Thorvardur Jon Love, Sigurdur Y Kristinsson
Publikováno v:
Blood. 140:261-263