Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sigurdur Magnusson"'
Autor:
Astros Skuladottir, Gyda Bjornsdottir, Egil Ferkingstad, Gudmundur Einarsson, Lilja Stefansdottir, Muhammad Sulaman Nawaz, Thorunn Olafsdottir, Saedis Saevarsdottir, G. Walters, Sigurdur Magnusson, Asmundur Oddson, Anna Bjornsdottir, Olafur Sveinsson, Arnor Vikingsson, Thomas Hansen, Rikke Jacobsen, Christian Erikstrup, Michael Schwinn, Søren Brunak, Karina Banasik, Sisse Ostrowski, Anders Troelsen, Cecilie Henkel, Ole Pedersen, Ingileif Jonsdottir, Daniel Gudbjartsson, Patrick Sulem, Thorgeir Thorgeirsson, Hreinn Stefansson, Kari Stefansson
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy and has a largely unknown underlying biology. In a genome-wide association study of CTS (Ncases = 48,843, Ncontrols = 1,190,837), we found 53 sequence variants at 50 loci that asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a822845757013b125227db5d4321f9
https://doi.org/10.21203/rs.3.rs-1189337/v1
https://doi.org/10.21203/rs.3.rs-1189337/v1
Autor:
Douglas P, Wightman, Iris E, Jansen, Jeanne E, Savage, Alexey A, Shadrin, Shahram, Bahrami, Dominic, Holland, Arvid, Rongve, Sigrid, Børte, Bendik S, Winsvold, Ole Kristian, Drange, Amy E, Martinsen, Anne Heidi, Skogholt, Cristen, Willer, Geir, Bråthen, Ingunn, Bosnes, Jonas Bille, Nielsen, Lars G, Fritsche, Laurent F, Thomas, Linda M, Pedersen, Maiken E, Gabrielsen, Marianne Bakke, Johnsen, Tore Wergeland, Meisingset, Wei, Zhou, Petroula, Proitsi, Angela, Hodges, Richard, Dobson, Latha, Velayudhan, Karl, Heilbron, Adam, Auton, Julia M, Sealock, Lea K, Davis, Nancy L, Pedersen, Chandra A, Reynolds, Ida K, Karlsson, Sigurdur, Magnusson, Hreinn, Stefansson, Steinunn, Thordardottir, Palmi V, Jonsson, Jon, Snaedal, Anna, Zettergren, Ingmar, Skoog, Silke, Kern, Margda, Waern, Henrik, Zetterberg, Kaj, Blennow, Eystein, Stordal, Kristian, Hveem, John-Anker, Zwart, Lavinia, Athanasiu, Per, Selnes, Ingvild, Saltvedt, Sigrid B, Sando, Ingun, Ulstein, Srdjan, Djurovic, Tormod, Fladby, Dag, Aarsland, Geir, Selbæk, Stephan, Ripke, Kari, Stefansson, Ole A, Andreassen, Peter, Wilton
Publikováno v:
Nature genetics. 53(9)
Late-onset Alzheimer's disease is a prevalent age-related polygenic disease that accounts for 50-70% of dementia cases. Currently, only a fraction of the genetic variants underlying Alzheimer's disease have been identified. Here we show that increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea03a23dd17cfba5d7bce1df1a06df05
https://pubmed.ncbi.nlm.nih.gov/35726068
https://pubmed.ncbi.nlm.nih.gov/35726068
Publikováno v:
Fish Physiology and Biochemistry. 13:119-132
Effects of different incubation temperatures (2, 8, 14 and 20°C) and hepatocyte membrane fatty acid composition on the rate of internalization and lysosomal degradation of the ligand, mannosylated albumin, that is taken up by receptor-mediated endoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca492c47d686286c3f2c7bbd3d9a2a4
https://doi.org/10.1007/bf00004337
https://doi.org/10.1007/bf00004337
Autor:
T. Berg, Sigurdur Magnusson
Publikováno v:
Biochemical Journal. 291:749-755
Upon intravenous injection into rats, the plant toxin ricin was rapidly cleared from the circulation by the liver. Among the different liver cell populations, most of the injected ricin associated with the sinusoidal endothelial cells (EC), whereas t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a521654d14b93a56a0a33eeb3ca8e199
https://doi.org/10.1042/bj2910749
https://doi.org/10.1042/bj2910749
Publikováno v:
Experimental Cell Research. 205:118-125
We have studied the characteristics of internalization and intracellular transport of ricin via two distinct pathways in rat liver endothelial cells (EC), i.e., via binding to mannose receptors and surface galactosyl-residues, respectively. Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c904f591adef66193aafbab65aa907d
https://doi.org/10.1006/excr.1993.1065
https://doi.org/10.1006/excr.1993.1065
Characterization of retroendocytosis in rat liver parenchymal cells and sinusoidal endothelial cells
Publikováno v:
Biochemical Journal. 287:241-246
After receptor-mediated endocytosis, internalized ligands may be recycled to the cell surface instead of being routed to lysosomes for degradation, a process termed retroendocytosis. We have investigated the kinetics and extent of retroendocytosis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa43c110268b3f9c28a435b499833a0c
https://doi.org/10.1042/bj2870241
https://doi.org/10.1042/bj2870241
Publikováno v:
Endocytosis ISBN: 9783642842979
Hepatic lysosomal heterogeneity is partly due to differences between lysosomes in the different types of liver cells. It has been shown, for instance, that the composition and contents of various lysosomal enzyme activities are distinctly different i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88819c646dc244545c72ec77565e85bc
https://doi.org/10.1007/978-3-642-84295-5_30
https://doi.org/10.1007/978-3-642-84295-5_30
Publikováno v:
The Biochemical journal. 277
We have investigated the interactions of the plant toxin ricin with sinusoidal endothelial rat liver cells (EC). In these cells, ricin can be bound and internalized via either cell surface galactosyl residues or mannose receptors. Binding and uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5083cda3960659709fbfe4901b5c89bc
https://pubmed.ncbi.nlm.nih.gov/1908224
https://pubmed.ncbi.nlm.nih.gov/1908224
Publikováno v:
Micron and Microscopica Acta. 22:27-28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d70cf0230d3be61ea1e649dfdddbb7a
https://doi.org/10.1016/0739-6260(91)90074-a
https://doi.org/10.1016/0739-6260(91)90074-a
Publikováno v:
Micron and Microscopica Acta. 22:95-96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6edfdd995a8ce2c568255e67438f668d
https://doi.org/10.1016/0739-6260(91)90108-c
https://doi.org/10.1016/0739-6260(91)90108-c