Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sigurd E. Hoelsbrekken"'
Publikováno v:
The New England journal of medicine. 387(1)
Autor:
Ståle B. Myhrvold, Espen F. Brouwer, Tor K. M. Andresen, Karin Rydevik, Madeleine Amundsen, Wolfram Grün, Faisal Butt, Morten Valberg, Svend Ulstein, Sigurd E. Hoelsbrekken
Publikováno v:
The New England journal of medicine. 386(15)
Background Whether surgical repair of an acute Achilles’ tendon rupture by an open-repair or minimally invasive approach is associated with better outcomes than nonsurgical treatment is not clear. Methods We performed a multicenter, randomized, con
Autor:
Sigurd E. Hoelsbrekken, Elisabeth Gyllensten Bjørnsen, Michael R. Daws, Erik Dissen, Per C. Saether, Daniela Pende, Sigbjørn Fossum, Lavanya Thiruchelvam-Kyle
Publikováno v:
The Journal of Immunology. 198:2556-2567
The functions of activating members of the killer cell Ig-like receptor (KIR) family are not fully understood, as the ligands for these receptors are largely unidentified. In this study, we report that KIR2DS2 reporter cells recognize a ligand expres
Autor:
Erik Dissen, Camilla Henden, Preben Boysen, Lavanya Thiruchelvam-Kyle, Sigurd E. Hoelsbrekken, Elisabeth Gyllensten Bjørnsen, Per C. Saether, Michael R. Daws
NK cells kill cancer cells and infected cells upon activation by cell surface receptors. Human NKp30 is an activating receptor expressed by all mature NK cells. The B7 family member B7H6 has been identified as one ligand for NKp30. Several alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948d12174d0c57a7c0efc36d1c7d9e0b
http://hdl.handle.net/11250/2586921
http://hdl.handle.net/11250/2586921
Autor:
Lavanya, Thiruchelvam-Kyle, Sigurd E, Hoelsbrekken, Per C, Saether, Elisabeth Gyllensten, Bjørnsen, Daniela, Pende, Sigbjørn, Fossum, Michael R, Daws, Erik, Dissen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(7)
The functions of activating members of the killer cell Ig-like receptor (KIR) family are not fully understood, as the ligands for these receptors are largely unidentified. In this study, we report that KIR2DS2 reporter cells recognize a ligand expres
Autor:
Sigurd E. Hoelsbrekken, Per C. Saether, James C. Ryan, Erik Dissen, Øyvind Nylenna, Sigbjørn Fossum, Imer Ö. Slettedal
Publikováno v:
The Journal of Immunology. 170:2259-2263
We report the molecular cloning of a KIR3DL1 receptor in the mouse and the rat, between 37.4 and 45.4% identical with primate killer cell Ig-like receptors (KIRs/CD158). Both mouse and rat molecules contain a pair of immunoreceptor tyrosine-based inh
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(12)
Signaling by the CD94/NKG2 heterodimeric NK cell receptor family has been well characterized in the human but has remained unclear in the mouse and rat. In the human, the activating receptor CD94/NKG2C associates with DAP12 by an ionic bond between o
Publikováno v:
Seminars in immunology. 20(6)
Natural killer (NK) cells discriminate between normal syngeneic cells and infected, neoplastic or MHC-disparate allogeneic cells. The reactivity of NK cells appears to be regulated by a balance between activating receptors that recognize non-self or
Autor:
Sigurd E. Hoelsbrekken, Per C. Saether, Lewis L. Lanier, Ingunn H. Westgaard, Erik Dissen, Jonathan Benjamin, Sigbjørn Fossum
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 181(5)
NK cells identify infected, neoplastic, or MHC-disparate target cells via several different receptors. The NK cell receptor KLRE1 lacks known signaling motifs but has nevertheless been shown to regulate NK cell-mediated cytotoxicity. Here we demonstr
Publikováno v:
Immunogenetics. 57(7)
We report the molecular cloning of two novel single-member receptor families with homology to LILR/CD85, PIR, and gp49: LILRC1 in the rat and the mouse, and LILRC2 in the rat. LILRC1 and LILRC2 both have two extracellular Ig-like domains and a cytopl