Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Sigurd D. Süßmuth"'
Autor:
Luisa Carstens, Margot Popp, Christian Keicher, Rita Hertrampf, David Weigner, Marvin S. Meiering, Gerd Luippold, Sigurd D. Süssmuth, Christian F. Beckmann, Andreas Wunder, Simone Grimm
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Anhedonia and other deficits in reward- and motivation-related processing in psychiatric patients, including patients with major depressive disorder (MDD), represent a high unmet medical need. Neurobiologically, these deficits in
Externí odkaz:
https://doaj.org/article/72ba2aa885384bc1b70647a6e0390c56
Autor:
Matthias Michal, Andreas Schulz, Philipp S. Wild, Thomas Koeck, Thomas Münzel, Alexander K. Schuster, Konstantin Strauch, Karl Lackner, Sigurd D. Süssmuth, Heiko G. Niessen, Andreas Borta, Kelly A. Allers, Daniela Zahn, Manfred E. Beutel
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Previous studies reported significantly altered tryptophan catabolite concentrations in major depression. Thus, tryptophan catabolites were considered as potential biomarkers of depression and their modulators as potential targets for psycho
Externí odkaz:
https://doaj.org/article/40643a4100984f27990ac5b3287ed2f3
Autor:
Christian Schultheis, Holger Rosenbrock, Salome Rebecca Mack, Richard Vinisko, Niklas Schuelert, Andrea Plano, Sigurd D. Süssmuth
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Patients with schizophrenia experience cognitive impairment related to neural network dysfunction and deficits in sensory processing. These deficits are thought to be caused by N-methyl-D-aspartate receptor hypofunction and can be assessed i
Externí odkaz:
https://doaj.org/article/d265643591034c06942ab6cf0e78eec1
Autor:
Makbule Senel, Daniel Rapp, Benjamin Mayer, Sarah Jesse, Sigurd D. Süssmuth, Markus Otto, Jan Lewerenz, Hayrettin Tumani
Publikováno v:
Cells, Vol 9, Iss 10, p 2169 (2020)
To investigate whether and how cerebrospinal fluid (CSF) findings can contribute to distinguish tick-borne encephalitis (TBE) from herpes simplex virus (HSV) and varicella zoster virus (VZV) induced central nervous system (CNS) infections (HSV-I, VZV
Externí odkaz:
https://doaj.org/article/86b2a69f02714975a8800567a78d0f05
Autor:
Yuri Milaneschi, Brenda W.J.H. Penninx, Robert A. Schoevers, Heiko G. Niessen, Kelly A. Allers, Erik J. Giltay, Sigurd D. Süssmuth, Aartjan T.F. Beekman, Sascha Keller
Publikováno v:
Brain, Behavior, and Immunity, 97, 167-175. Academic Press Inc.
Milaneschi, Y, Allers, K A, Beekman, A T F, Giltay, E J, Keller, S, Schoevers, R A, Süssmuth, S D, Niessen, H G & Penninx, B W J H 2021, ' The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation ', Brain, Behavior, and Immunity, vol. 97, pp. 167-175 . https://doi.org/10.1016/j.bbi.2021.07.007
Brain, Behavior, and Immunity, 97, 167-175. ACADEMIC PRESS INC ELSEVIER SCIENCE
Brain behavior and immunity, 97, 167-175. ACADEMIC PRESS INC ELSEVIER SCIENCE
Milaneschi, Y, Allers, K A, Beekman, A T F, Giltay, E J, Keller, S, Schoevers, R A, Süssmuth, S D, Niessen, H G & Penninx, B W J H 2021, ' The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation ', Brain, Behavior, and Immunity, vol. 97, pp. 167-175 . https://doi.org/10.1016/j.bbi.2021.07.007
Brain, Behavior, and Immunity, 97, 167-175. ACADEMIC PRESS INC ELSEVIER SCIENCE
Brain behavior and immunity, 97, 167-175. ACADEMIC PRESS INC ELSEVIER SCIENCE
Background: Tryptophan catabolites ("TRYCATs") produced by the kynurenine pathway (KP) may play a role in depression pathophysiology. Studies comparing TRYCATs levels in depressed subjects and controls provided mixed findings. We examined the associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b038c19f3037c1af5021a89cf3c7e702
https://doi.org/10.1016/j.bbi.2021.07.007
https://doi.org/10.1016/j.bbi.2021.07.007
Autor:
Kathrin Malejko, Patrick Weydt, Sigurd D Süßmuth, Georg Grön, Bernhard G Landwehrmeyer, Birgit Abler
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114569 (2014)
Functional compensation demonstrated as mechanism to offset neuronal loss in early Alzheimer disease may also occur in other adult-onset neurodegenerative diseases, particularly Huntington disease (HD) with its genetic determination and gradual chang
Externí odkaz:
https://doaj.org/article/732871606dc94e47a767e786aef2b0a0
Autor:
Hayrettin Tumani, Sigurd D. Süssmuth
Publikováno v:
Neuromethods ISBN: 9781071613184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::385da7930e26d1bfe612092ee43adff0
https://doi.org/10.1007/978-1-0716-1319-1_1
https://doi.org/10.1007/978-1-0716-1319-1_1
Publikováno v:
Biological Psychiatry. 91:S379
Autor:
Martin Gorges, Michael Orth, Sigurd D. Süßmuth, Robert Christian Wolf, G. Bernhard Landwehrmeyer, Hans-Peter Müller, Jan Kassubek, Georg Grön
Publikováno v:
Journal of Neurology. 263:539-549
In Huntington's disease, the relationship of brain structure, brain function and clinical measures remains incompletely understood. We asked how sensory-motor network brain structure and neural activity relate to each other and to motor performance.
Autor:
William Mallonee, Thomas T. Warner, Vicki L. Wheelock, Emily P. Freney, Stephen M. Rao, Vincent A. Magnotta, Alma Macaraeg, Sigurd D. Süßmuth, Paula Wasserman, Shineeka Smith, Phil Danzer, Anne Elizabeth Rosser, Michael D. Geschwind, Brenton Maxwell, Kelsey Montross, Gabriella Satris, Albie Law, Daniel S. O'Leary, David J. Moser, Thomas Brashers-Krug, Janessa O. Carvalho, Hans J. Johnson, Martha Nance, Anita M.Y. Goh, Mark Guttman, J. Preston, Janet K. Williams, Judith Bek, Susan Perlman, Alanna Sheinberg, Wenjing Lu, Christine Reece, Pietro Mazzoni, Nadine Yoritomo, Elizabeth Aylward, W.R. Wayne Martin, Megan M. Smith, Phyllis Chua, J. Decolongon, Breanna Nickels, Pamela King, Deborah L. Harrington, Roland Zschiegner, Brian Clemente, David G. Gunn, Alex Bura, Vivien Vaughan, Samantha M Loi, Maggie Burrows, Kimberly A. Quaid, Jillian McMillan, Jason Evans, Michael Orth, Mary Wodarski, Courtney Shadrick, Sarah L Mason, H. Jeremy Bockholt, Marguerite Wieler, Elizabeth Howard, Melissa Wesson, Kathy Price, Lisa Kjer, Daniela Rae, Lynn A. Raymond, Roger A. Barker, Edmond Chiu, Holly Westervalt, Joanne Wojcieszek, Stephanie Antonopoulos, Ji In Kim, Jane S. Paulsen, Maryjane Ong, Spencer Lourens, Maria Tedesco, Katrin Barth, Christina Reeves, Jane Griffith, Peter K. Panegyres, Sarah Hunt, Cathy Wood-Siverio, David Craufurd, Holly James Westervelt, Zosia Miedzybrodzka, A. Coleman, Irita Karmalkar, Joseph W. Y. Lee, Carolin Eschenbach, Greg Suter, Christopher A. Ross, Satwinder Sran, Sharon J. Sha, Daniela Schwenk, Joel S. Perlmutter, Ali Samii, James A. Mills, Mark Varvaris, Amanda Miller, Frederick J. Marshall, Amy M. Chesire, Isabella De Soriano, Ying Zhang, Natalie Valle Guzman, Angela Komiti, Oksana Suchowersky, Clement T. Loy, Diane Erickson, Karen Marder, Lyla Mourany, Joseph Winer, Anwar Ahmed, Jatin G. Vaidya, Eun Young Kim, Stacey K. Barton, Cheryl Erwin, Sonja Trautmann, Amanda Martin, Stewart A. Factor, Elizabeth McCusker, Mariella D'Alessandro, Jeffrey D. Long, Randi Jones, Nancy R. Downing, Jared M. Bruce, Charlyne Hickey, Rajeev Kumar, Mannie Fan, Sarah E Tomaszewski Farias
Publikováno v:
J Clin Exp Neuropsychol
Huntington disease (HD) is a neurodegenerative condition with prominent motor (including oculomotor), cognitive, and psychiatric effects. While neuropsychological deficits are present in HD, motor impairments may impact performance on neuropsychologi