Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sigurd, Braun"'
Autor:
Hiroshi Kanno, Kotaro Hiramatsu, Hideharu Mikami, Atsushi Nakayashiki, Shota Yamashita, Arata Nagai, Kohki Okabe, Fan Li, Fei Yin, Keita Tominaga, Omer Faruk Bicer, Ryohei Noma, Bahareh Kiani, Olga Efa, Martin Büscher, Tetsuichi Wazawa, Masahiro Sonoshita, Hirofumi Shintaku, Takeharu Nagai, Sigurd Braun, Jessica P. Houston, Sherif Rashad, Kuniyasu Niizuma, Keisuke Goda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Flow cytometry is a vital tool in biomedical research and laboratory medicine. However, its accuracy is often compromised by undesired fluctuations in fluorescence intensity. While fluorescence lifetime imaging microscopy (FLIM) bypasses thi
Externí odkaz:
https://doaj.org/article/9e141a3a3e5140768e9b58bd2c11814e
Autor:
Merve Öztürk, Anja Freiwald, Jasmin Cartano, Ramona Schmitt, Mario Dejung, Katja Luck, Bassem Al-Sady, Sigurd Braun, Michal Levin, Falk Butter
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Protein abundance is controlled at the transcriptional, translational and posttranslational levels. Here, Öztürk et al. determine proteome changes resulting from individual knockout of 3308 nonessential genes in the yeast S. pombe, infer gene funct
Externí odkaz:
https://doaj.org/article/cc8b9e1891fd454eb5a550f15ddb06fb
Autor:
Matías Capella, Imke K. Mandemaker, Lucía Martín Caballero, Fabian den Brave, Boris Pfander, Andreas G. Ladurner, Stefan Jentsch, Sigurd Braun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
rDNA repeats residing in the nucleolus must be released to the nucleoplasm to allow repair by homologous recombination. Here the authors reveal insights into the molecular mechanism proposing that phosphorylation and SUMOylation of the rDNA-tethering
Externí odkaz:
https://doaj.org/article/7c25cbe4fae14af59e6291014ce9f3bc
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1010201 (2022)
Heterochromatin spreading, the expansion of repressive chromatin structure from sequence-specific nucleation sites, is critical for stable gene silencing. Spreading re-establishes gene-poor constitutive heterochromatin across cell cycles but can also
Externí odkaz:
https://doaj.org/article/c279fc246faa4e728cffd6da8d967cd0
Publikováno v:
Microbial Cell, Vol 7, Iss 3, Pp 80-92 (2020)
Maintaining the identity of chromatin states requires mechanisms that ensure their structural integrity through the concerted actions of histone modifiers, readers, and erasers. Histone H3K9me and H3K27me are hallmarks of repressed heterochromatin, w
Externí odkaz:
https://doaj.org/article/a1043ddff8704ecbb1f2e12639c1eaed
Autor:
Magdalena Murawska, R.A. Greenstein, Tamas Schauer, Karl C.F. Olsen, Henry Ng, Andreas G. Ladurner, Bassem Al-Sady, Sigurd Braun
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109944- (2021)
Summary: Heterochromatin formation requires three distinct steps: nucleation, self-propagation (spreading) along the chromosome, and faithful maintenance after each replication cycle. Impeding any of those steps induces heterochromatin defects and im
Externí odkaz:
https://doaj.org/article/d053a21db4ae458c81001d81be4d5d4d
Autor:
Anna Schmücker, Bingkun Lei, Zdravko J Lorković, Matías Capella, Sigurd Braun, Pierre Bourguet, Olivier Mathieu, Karl Mechtler, Frédéric Berger
Publikováno v:
PLoS Genetics, Vol 17, Iss 6, p e1009601 (2021)
Selection of C-terminal motifs participated in evolution of distinct histone H2A variants. Hybrid types of variants combining motifs from distinct H2A classes are extremely rare. This suggests that the proximity between the motif cases interferes wit
Externí odkaz:
https://doaj.org/article/4bb13fccf7bd4709836d091ade8013c8
Autor:
Magdalena Murawska, Sigurd Braun
Publikováno v:
Trends in Genetics. 38:646-649
The multitasking histone chaperone FACT (FAcilitates Chromatin Transcription) contributes to actively transcribed euchromatin and repressed heterochromatin. However, its precise role in gene silencing has remained obscure. Here, we discuss new insigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cae4dc6367aa4b37076860767d059aa
https://doi.org/10.1016/j.tig.2022.02.011
https://doi.org/10.1016/j.tig.2022.02.011
Autor:
Ramón Ramos Barrales, Sigurd Braun
Publikováno v:
Microbial Cell, Vol 3, Iss 4, Pp 185-188 (2016)
Transcriptionally repressed chromatin localizes to specific areas within the eukaryotic nucleus and is often found at the nuclear periphery, which is thought to provide a specialized compartment for gene silencing. However, the molecular mechanisms t
Externí odkaz:
https://doaj.org/article/fc3a5880a81646bb8797017f1b4b9fc0
Autor:
Sabine Fischer-Burkart, Yoshiyuki Hirano, Yasuha Kinugasa, Matías Capella, Nikolay Dobrev, Tamás Fischer, Ramón R. Barrales, Irmgard Sinning, Sigurd Braun, van Emden T, Lucía Martín Caballero, Yasushi Hiraoka
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 29 (9), pp.910-921. ⟨10.1038/s41594-022-00831-6⟩
Nature Structural and Molecular Biology, 2022, 29 (9), pp.910-921. ⟨10.1038/s41594-022-00831-6⟩
Transcriptionally silent chromatin often localizes to the nuclear periphery. However, whether the nuclear envelope (NE) is a site for post-transcriptional gene repression is not well understood. Here we demonstrate that Schizosaccharomyces pombe Lem2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478dd6336fc4a860c14649591543fb92
http://hdl.handle.net/10261/288565
http://hdl.handle.net/10261/288565