Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sigrun Knöchel"'
Publikováno v:
The EMBO Journal. 26:2942-2954
VegT and beta-Catenin are key players in the hierarchy of factors that are required for induction and patterning of mesendoderm in Xenopus embryogenesis. By descending the genetic cascades, cells lose their pluripotent status and are determined to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3259dad0e25f456862c6108a5a7670
https://doi.org/10.1038/sj.emboj.7601736
https://doi.org/10.1038/sj.emboj.7601736
Publikováno v:
Mechanisms of Development. 117:283-287
We report on the temporal and spatial expression pattern of two novel genes of the Xenopus fork head/winged helix family, xFoxB2 and xFoxI1c. xFoxB2 is activated at the late blastula stage and first expressed within the dorsolateral ectoderm except f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c68e4801ad9097688b4c88ea391cc8
https://doi.org/10.1016/s0925-4773(02)00184-3
https://doi.org/10.1016/s0925-4773(02)00184-3
Publikováno v:
Mechanisms of Development. 109(1):79-82
The Xenopus tropicalis BMP-2 and BMP-4 genes have been cloned and sequenced. A comparison with the corresponding genes from X. laevis reveals that the BMP-4 genes are conserved at a higher extent than the BMP-2 genes. This is especially evident for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d7a73eb4c2f85ee00d5656665722de
Publikováno v:
Mechanisms of Development. 98:29-36
Zygotic expression of the BMP-4 gene in Xenopus embryos is regulated by an auto-regulatory loop. Since AP-1 is known as a mediator of auto-regulatory loops both in the case of the Drosophila dpp and the mammalian TGF-b genes, we have analysed the pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8636f9590c647b134ef68db5a6802d
https://doi.org/10.1016/s0925-4773(00)00448-2
https://doi.org/10.1016/s0925-4773(00)00448-2
Publikováno v:
Mechanisms of Development. 74:29-39
The Xenopus laevis BMP-4 gene shows an evolutionary conserved structure containing two coding exons and a leader exon. The transcripts which are detected after zygotic activation of the gene in ventral mesoderm of late blastula stage embryos do eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d28d0e7b34be836888f0650caa1d096
https://doi.org/10.1016/s0925-4773(98)00059-8
https://doi.org/10.1016/s0925-4773(98)00059-8
Autor:
Jutta Lef, Walter Knöchel, Joachim H. Clement, Bernward Klocke, Sigrun Knöchel, Sigurd Hille, Manfred Köster
Publikováno v:
Mechanisms of Development. 38:157-165
A gene family encoding the fork head/HNF-3 domain has been identified in the South African clawed frog, Xenopus laevis. Screening of genomic DNA and gastrula stage derived cDNA libraries with a DNA fragment encoding the Drosophila fork head domain le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9626f607ee36055a2b76634f192ac650
https://doi.org/10.1016/0925-4773(92)90007-7
https://doi.org/10.1016/0925-4773(92)90007-7
Publikováno v:
Mechanisms of development. 123(1)
The active form of the Xenopus X-box binding protein 1 (xXBP1) partially synergizes and partially antagonizes with BMP-4 signaling. xXBP1 overexpression inhibits mesoderm differentiation and formation of neural tissues. A functional knockdown promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9081ef269b8c64256b3d70875fd36c
https://pubmed.ncbi.nlm.nih.gov/16278078
https://pubmed.ncbi.nlm.nih.gov/16278078
Publikováno v:
The Journal of biological chemistry. 279(42)
The Xvent-2B promoter is regulated by a BMP-2/4-induced transcription complex comprising Smad signal transducers and specific transcription factors. Using a yeast one-hybrid screen we have found that Oct-25, a Xenopus POU domain protein related to ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb546971392d50b410e1b611c72addb
https://pubmed.ncbi.nlm.nih.gov/15292233
https://pubmed.ncbi.nlm.nih.gov/15292233
Publikováno v:
The Journal of biological chemistry. 275(44)
Like other genes of the transforming growth factor-beta family, the BMP-4 gene is regulated by an autocatalytic loop. In Xenopus embryos this loop can be ectopically induced by injection of BMP-2 RNA. However, cycloheximide treatment subsequent to BM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd11668e4c551c89fc7e387ede5d4914
https://pubmed.ncbi.nlm.nih.gov/10938274
https://pubmed.ncbi.nlm.nih.gov/10938274
Publikováno v:
Mechanisms of development. 52(2-3)
The temporal and spatial transcription patterns of the Xenopus laevis Bone morphogenetic protein 2 (BMP-2) gene have been investigated. Unlike the closely related BMP-4 gene, the BMP-2 gene is strongly transcribed during oogenesis. Besides some enric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0968c2c05901dbcef5683362692fa6
https://pubmed.ncbi.nlm.nih.gov/8541221
https://pubmed.ncbi.nlm.nih.gov/8541221