Seizure control after late introduction of anakinra in a patient with adult onset Rasmussen’s encephalitis

Autor: Monika Mochol, Erik Taubøll, Line Sveberg, Bjørn Tennøe, Ketil Berg Olsen, Kjell Heuser, Sigrid Svalheim

Publikováno v: Epilepsy & Behavior Reports, Vol 16, Iss , Pp 100462- (2021)

Neuroinflammation has been considered an important pathophysiological process involved in epileptogenesis and may provide possibilities for new treatment possibilities. We present the case of a 45-year-old female with drug resistant epilepsy and prog

Externí odkaz: https://doaj.org/article/5fb6f82bbc1c4cac9fbf11513b17c08c

Lamotrigine effects on immune gene expression in larval zebrafish

Autor: Erik Taubøll, Thomas W.K. Fraser, Sigrid Svalheim, Erik Ropstad, Cecilie Johannessen Landmark, Monika Mochol, Paul Whatmore

Publikováno v: Epilepsy Research

Purpose: Despite growing evidence that neuroinflammation and pro-inflammatory cytokines are involved in the pathogenesis of seizures and epilepsy, this knowledge has not been incorporated in the proposed mechanism of action of any of the current anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603abf1a6f50cab230dda437a447bd2c
https://hdl.handle.net/11250/2986206

Seizure control after late introduction of anakinra in a patient with adult onset Rasmussen’s encephalitis

Autor: Sigrid Svalheim, Ketil Berg Olsen, Line Sveberg, Erik Taubøll, Kjell Heuser, Bjørn Tennøe, Monika Mochol

Publikováno v: Epilepsy & Behavior Reports, Vol 16, Iss, Pp 100462-(2021)
Epilepsy & Behavior Reports

Highlights • Ten percentage of patient with RE has adult onset of symptoms. • Experience with IL-1Ra like anakinra in RE patients is limited. • 26 years after RE onset anakinra was introduced and led to complete seizure control. • Premature w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555400793fd412143b2e0e367a4873c4
http://www.sciencedirect.com/science/article/pii/S2589986421000368

Influence of valproate-induced hyperammonemia on treatment decision in an adult status epilepticus cohort

Autor: Erik Taubøll, Line Bédos Ulvin, Sigrid Svalheim, Sarah Folkestad Habhab, Kjell Heuser, Ketil Berg Olsen, Morten Andreas Horn

Publikováno v: Habhab, S F, Ulvin, L B, Taubøll, E, Svalheim, S, Olsen, K B, Horn, M A & Heuser, K 2020, ' Influence of valproate-induced hyperammonemia on treatment decision in an adult status epilepticus cohort ', Epilepsy and Behavior, vol. 111, 107193 . https://doi.org/10.1016/j.yebeh.2020.107193

Introduction Status epilepticus (SE) is a neurological emergency in which immediate intervention is required to prevent permanent brain damage and death. Intravenous (IV) valproic acid (VPA) is often used for the treatment of SE. However, IV VPA freq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dfecab5441878fb9641c435f3b1cc6
https://pubmed.ncbi.nlm.nih.gov/32759060

Experimental models for the study of hormonal changes in epilepsy

Autor: Sigrid Svalheim, Kjell Heuser, Erik Taubøll, Line Sveberg

Publikováno v: Zeitschrift für Epileptologie. 28:246-253

Reproductive endocrine dysfunction is common among both women and men with epilepsy. The reasons for this are multifactorial and bidirectional; epilepsy can affect hormones, and hormones can affect seizures. Furthermore, several antiepileptic drugs (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f718ff5fcadaf5565523377fe77a8d
https://doi.org/10.1007/s10309-015-0001-x