Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Sigrid Stroobants"'
Autor:
Magdalena Mileva, Elisabeth G. E. de Vries, Thomas Guiot, Zéna Wimana, Anne-Leen Deleu, Carolien P. Schröder, Yolene Lefebvre, Marianne Paesmans, Sigrid Stroobants, Manon Huizing, Philippe Aftimos, Jolien Tol, Winette T. A. Van der Graaf, Wim J. G. Oyen, Danielle J. Vugts, C. Willemien Menke-van der Houven van Oordt, Adrienne H. Brouwers, Martine Piccart-Gebhart, Patrick Flamen, Géraldine Gebhart
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Efficacy of the human epidermal growth factor receptor (HER)2-targeting trastuzumab emtansine (T-DM1) in breast cancer (BC) relies on HER2 status determined by immunohistochemistry or fluorescence in-situ hybridization. Heterogeneity in HER2
Externí odkaz:
https://doaj.org/article/b8159ecb1674471b9a212c77843626e6
Autor:
Karuna Adhikari, Jonatan Dewulf, Christel Vangestel, Pieter Van der Veken, Sigrid Stroobants, Filipe Elvas, Koen Augustyns
Publikováno v:
ACS Omega, Vol 8, Iss 41, Pp 38252-38262 (2023)
Externí odkaz:
https://doaj.org/article/eb3942f162174473a450163bce286f3a
Autor:
Taco Metelerkamp Cappenberg, Stijn De Schepper, Christel Vangestel, Stef De Lombaerde, Leonie wyffels, Tim Van den Wyngaert, Jeffrey Mattis, Brian Gray, Koon Pak, Sigrid Stroobants, Filipe Elvas
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Background Imaging of cell death can provide an early indication of treatment response in cancer. [99mTc]Tc-Duramycin is a small-peptide SPECT tracer that recognizes both apoptotic and necrotic cells by binding to phosphatidylethanolamine pr
Externí odkaz:
https://doaj.org/article/5e5aa09daddc4fbdbefd750b6971e189
Autor:
Lennert Boeckxstaens, Elin Pauwels, Vincent Vandecaveye, Wies Deckers, Frederik Cleeren, Jeroen Dekervel, Timon Vandamme, Kim Serdons, Michel Koole, Guy Bormans, Annouschka Laenen, Paul M. Clement, Karen Geboes, Eric Van Cutsem, Kristiaan Nackaerts, Sigrid Stroobants, Chris Verslype, Koen Van Laere, Christophe M. Deroose
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Background Fluorine-18-labeled SSAs have the potential to become the next-generation tracer in SSTR-imaging in neuroendocrine tumor (NET) patients given their logistical advantages over the current gold standard gallium-68-labeled SSAs. In p
Externí odkaz:
https://doaj.org/article/488c4094d49d4d999e7ac7b3db986476
Autor:
Rani Robeyns, Angela Sisto, Elias Iturrospe, Katyeny Manuela da Silva, Maria van de Lavoir, Vincent Timmerman, Adrian Covaci, Sigrid Stroobants, Alexander L. N. van Nuijs
Publikováno v:
Metabolites, Vol 14, Iss 5, p 248 (2024)
Torin1, a selective kinase inhibitor targeting the mammalian target of rapamycin (mTOR), remains widely used in autophagy research due to its potent autophagy-inducing abilities, regardless of its unspecific properties. Recognizing the impact of mTOR
Externí odkaz:
https://doaj.org/article/739793a46fab4b7c926ef1fe9f523065
Autor:
Frederik Soffers, Nils Helsen, Tim Van den Wyngaert, Laurens Carp, Otto S. Hoekstra, Laurence Goethals, Michel Martens, Kristof Deben, Karoline Spaepen, Remco De Bree, Frank De Geeter, G. J. C. Zwezerijnen, Carl Van Laer, Alex Maes, Olivier Lenssen, Sigrid Stroobants, the ECLYPS Investigators
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Background FDG-PET/CT has a high negative predictive value to detect residual nodal disease in patients with locally advanced squamous cell head and neck cancer after completing concurrent chemoradiotherapy (CCRT). However, the positive pred
Externí odkaz:
https://doaj.org/article/e9ba60f4f41e45a5a02c65b9b2f9bdd9
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The linear parametric neurotransmitter positron emission tomography (lp-ntPET) kinetic model can be used to detect transient changes (activation) in endogenous neurotransmitter levels. Preclinical PET scans in awake animals can be performed to invest
Externí odkaz:
https://doaj.org/article/e96d0e7a907943a4b506e220a6ac16e3
Autor:
Dorien Glorie, Jeroen Verhaeghe, Alan Miranda, Stef De Lombaerde, Sigrid Stroobants, Steven Staelens
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Background Currently, the evidence on synaptic abnormalities in neuropsychiatric disorders—including obsessive–compulsive disorder (OCD)—is emerging. The newly established positron emission tomography (PET) ligand ((R)-1-((3-((11)C-met
Externí odkaz:
https://doaj.org/article/e74c766476b44ad69df8336b5e8e269e
Autor:
Eduardo Ruivo, Filipe Elvas, Karuna Adhikari, Christel Vangestel, Glenn Van Haesendonck, Filip Lemière, Steven Staelens, Sigrid Stroobants, Pieter Van der Veken, Leonie wyffels, Koen Augustyns
Publikováno v:
ACS Omega, Vol 5, Iss 9, Pp 4449-4456 (2020)
Externí odkaz:
https://doaj.org/article/67db9c5384724660a66407972f59779d
Autor:
Farnaz Sedigheh Takhsha, Christel Vangestel, Muhammet Tanc, Sven De Bruycker, Maya Berg, Isabel Pintelon, Sigrid Stroobants, Guido R. Y. De Meyer, Pieter Van Der Veken, Wim Martinet
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Resistance against anti-cancer therapy is one of the major challenges during treatment of multiple cancers. Gemcitabine is a standard first-line chemotherapeutic drug, yet autophagy is highly activated in the hypoxic microenvironment of solid tumors
Externí odkaz:
https://doaj.org/article/55fbe685450a4b71836730ffe552e10b