Decreased serum concentrations of antiseizure medications in children with drug resistant epilepsy following treatment with ketogenic diet

Autor: Sigrid Pedersen, Magnhild Kverneland, Knut Rudi, Kristina Gervin, Cecilie Johannessen Landmark, Per Ole Iversen, Kaja Kristine Selmer

Publikováno v: Epilepsia Open, Vol 8, Iss 3, Pp 858-866 (2023)

Abstract Objective To examine the potential influence of a ketogenic diet on serum concentrations of antiseizure medications (ASMs) in children with drug resistant epilepsy. Methods We investigated the serum concentrations of ASMs in 25 children with

Externí odkaz: https://doaj.org/article/13ef7f1ede34443ebe667428f9534f95

Microbiota-gut brain axis involvement in neuropsychiatric disorders

Autor: Hervé M. Blottière, Emilio Russo, Sigrid Pedersen, Francesca Ronchi, Luigi Francesco Iannone, Gaia Luongo, Federico Zara, Cinzia Ferraris, P. Mainardi, Anna Tagliabue, Alberto Preda, Gerard Clarke, Kaja Kristine Selmer, Elisa Santocchi, Stefania Provasi, Vincenzo Belcastro, Carmen Giordano, Alberto Verrotti, Pietro Baldelli, Carlo Minetti, Rita Citraro, Diego Albani, Pasquale Striano, Andrea Petretto, Paola Iannetti, Marco Carotenuto, Jakob Zimmermann, Nicola Segata, Annamaria Cattaneo, Alberto Spalice, Letizia Guiducci, Sanjay M. Sisodiya

Publikováno v: Expert Review of Neurotherapeutics
Expert Review of Neurotherapeutics, Expert Reviews (formerly Future Drugs), 2019, 19 (10), pp.1037-1050. ⟨10.1080/14737175.2019.1638763⟩

International audience; Introduction: The microbiota-gut brain (MGB) axis is the bidirectional communication between the intestinal microbiota and the brain. An increasing body of preclinical and clinical evidence has revealed that the gut microbial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5eb870e08332698ab31c239d178fc15
https://pubmed.ncbi.nlm.nih.gov/31650879

Coffee inhibits nuclear factor-kappa B in prostate cancer cells and xenografts

Autor: Harald Carlsen, Ingvild Paur, Siv Kjølsrud Bøhn, Heidi Kiil Blomhoff, Marit Kolberg, Sigrid Pedersen, Kristine Lillebø Holm, Maiko Mitake, Rune Blomhoff

Publikováno v: The Journal of Nutritional Biochemistry. 27:153-163

Chronic inflammation contributes to prostate cancer and the transcription factor Nuclear Factor-kappa B (NF-κB) is constitutively active in most such cancers. We examine the effects of coffee on NF-κB and on the regulation of selected genes in huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c41607c0334e169dcc07822e64f3c6a
https://doi.org/10.1016/j.jnutbio.2015.08.028

Diettbehandling av epilepsi

Autor: Sigrid Pedersen, Ellen Molteberg, Anette Ramm-Pettersen, Karl O. Nakken, Magnhild Kverneland, Kathrine C. Haavardsholm

Publikováno v: Tidsskrift for Den norske legeforening.

Children with pharmacoresistant epilepsy should be offered ketogenic dietary therapy. The diet, which is rich in fat and low in carbohydrate, has a beneficial effect in reducing seizures in this patient group. It may also have a beneficial effect in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23b0b0703f87568ef477f79df67528eb
https://doi.org/10.4045/tidsskr.16.0486

Plant extracts of spices and coffee synergistically dampen nuclear factor-κB in U937 cells

Autor: Marit Kolberg, Rune Blomhoff, Trude Rakel Balstad, David R. Jacobs, Ingvild Paur, Sigrid Pedersen

Publikováno v: Nutrition research (New York, N.Y.). 33(10)

A large array of bioactive plant compounds (phytochemicals) has been identified and synergy among these compounds might contribute to the beneficial effects of plant foods. The transcription factor nuclear factor-κB (NF-κB) has been suggested as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aaef63e4839e02056cf67ca5cbda4dd
https://pubmed.ncbi.nlm.nih.gov/24074740