Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sigrid Kisling"'
Autor:
Lisa Gruber, Sigrid Kisling, Pia Lichti, François-Pierre Martin, Stephanie May, Martin Klingenspor, Martina Lichtenegger, Michael Rychlik, Dirk Haller
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71661 (2013)
BACKGROUND: Obesity has been associated with a more severe disease course in inflammatory bowel disease (IBD) and epidemiological data identified dietary fats but not obesity as risk factors for the development of IBD. Crohn's disease is one of the t
Externí odkaz:
https://doaj.org/article/151a5b4f5af2451dbeaf35349d16ce4c
Autor:
Christian Scherling, Hannelore Daniel, Dirk Haller, Michel Neunlist, Patrick Kollmann, Raphaël Moriez, Lisa Gruber, Sigrid Kisling, Michael Schemann, Gemma Mazzuoli, François Reichardt, Charlotte Baudry
Publikováno v:
The Journal of Physiology. 591:5125-5139
Key points • We investigated altered colonic functions in high fat diet-induced obesity in pre-diabetic mice. • After feeding an adipogenic diet for 12 weeks, accelerated colonic transit was associated with upregulation and enhanced signalling of
Autor:
Stefan Dübel, Jonas Zantow, Michael Hust, Sarah Just, Sigrid Kisling, Thomas Clavel, Ilias Lagkouvardos, Patricia Lepage
Publikováno v:
Scientific Reports (6), 1-13. (2016)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.1-13. ⟨10.1038/srep34337⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.1-13. ⟨10.1038/srep34337⟩
Pathogen infections, autoimmune diseases and chronic inflammatory disorders are associated with systemic antibody responses from the host immune system. Disease-specific antibodies can be important serum biomarkers, but the identification of antigens
Publikováno v:
Journal of General Virology. 86:1997-2006
Interleukin 1 (IL1) is an important regulator of inflammatory responses and contributes to host immune defence against infection. Vaccinia virus encodes a viral soluble IL1beta receptor (IL1betaR), which modulates the acute-phase host response to inf
Autor:
Klaus Wachinger, Claudia Börger, Uli Binder, Sigrid Kisling, Dirk Haller, Martin Schlapschy, Ina Theobald, Arne Skerra
Publikováno v:
Protein Engineering, Design and Selection
A major limitation of biopharmaceutical proteins is their fast clearance from circulation via kidney filtration, which strongly hampers efficacy both in animal studies and in human therapy. We have developed conformationally disordered polypeptide ch
Autor:
Stephanie May, Pia Lichti, François-Pierre Martin, Dirk Haller, Michael Rychlik, Sigrid Kisling, Martin Klingenspor, Lisa Gruber, Martina Lichtenegger
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e71661 (2013)
PLoS ONE, Vol 8, Iss 8, p e71661 (2013)
BACKGROUND: Obesity has been associated with a more severe disease course in inflammatory bowel disease (IBD) and epidemiological data identified dietary fats but not obesity as risk factors for the development of IBD. Crohn's disease is one of the t
Autor:
Jung-Su Chang, Dirk Haller, Emanuel Berger, Soeren Ocvirk, Sigrid Kisling, Amy S. Lee, Uli Binder, Arne Skerra
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 189(3)
Endoplasmic reticulum (ER) unfolded protein responses (UPR) are implicated in the pathogenesis of inflammatory bowel disease. Cytotoxic CD8αβ+ intraepithelial lymphocytes (IEL) contribute to the development of Crohn’s disease-like ileitis in TNF
Autor:
Jens Walter, Klaus Schuemann, Jung-Su Chang, Tanja Werner, Dirk Haller, Thomas Clavel, Inés Martínez, Sigrid Kisling, Stefan J. Wagner
Publikováno v:
Zeitschrift für Gastroenterologie. 49
Autor:
Sylvia Keller, Gunnar Loh, Steffen Wohlgemuth, Dirk Haller, Sigrid Kisling, Gerhard Jahreis, Mandy Stadion, Michael Blaut, Romy Kertscher
Publikováno v:
Gut microbes. 2(3)
Reduced gut microbiota diversity in conjunction with a bloom of few bacterial species is a common feature in inflammatory bowel disease (IBD) patients. However, the environmental changes caused by inflammation and their possible impact on the microbi
Autor:
Stefan J. Wagner, Thomas Clavel, Tanja Werner, Sigrid Kisling, Klaus Schuemann, Dirk Haller, Jens Walter, Jung-Su Chang, Inés Martínez
Publikováno v:
Gut. 60(3)
Background Iron replacement therapy is a common treatment in patients with anaemia and Crohn9s disease, but oral iron supplements are less tolerated. The pathogenesis of Crohn9s disease is attributed to intestinal bacteria and environmental factors t