Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sigrid Henke-Fahle"'
Autor:
Sigrid Henke-Fahle, Daniela Suesskind, Sven Schnichels, Bernd Wissinger, Sarah E. Coupland, Andreas Schatz, Karl U. Bartz-Schmidt, Sarah L. Lake
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 250:887-895
About 50% of patients with uveal melanoma (UM) develop metastases during the course of their disease. We analyzed serum levels of Growth Differentiation Factor-15 (GDF-15), with the aim of identifying patients with early metastases. GDF-15 concentrat
Autor:
Sigrid Henke-Fahle, Sylvia Bolz, Michal Fiedorowicz, Eberhart Zrenner, Focke Ziemssen, Sebastian Thaler, Ayseguel Tura, Frank Schuettauf, Tomasz Choragiewicz, Efdal Yoeruek, Karl Ulrich Bartz-Schmidt
Publikováno v:
Acta Ophthalmologica. 88:e170-e176
Purpose: To evaluate the effects of intravitreally introduced vascular endothelial growth factor (VEGF) inhibitors in rat eyes with healthy retinal ganglion cells (RGC) and into others with N-methyl-D-aspartate (NMDA)-induced RGC damage. Methods: Bev
Autor:
Bernhard K. Mueller, Philippe P. Monnier, Sylvie Julien, Henry Teng, Nardos G. Tassew, Sven Schnichels, Sigrid Henke-Fahle
Publikováno v:
Journal of Neuroscience Research. 86:531-536
Organotypic cultures of postnatal day 1 (P1) to P7 mouse cerebella are well-established models for studying cell survival. In the present work, we investigate the involvement of the Rho/ROCK intracellular pathway in Purkinje cell survival by using or
Autor:
Thomas Skutella, Sven Schnichels, Sylvie Julien, Sabine Conrad, Katrin Warstat, Sigrid Henke-Fahle, Ulrich Schraermeyer
Publikováno v:
Gene Expression Patterns. 8:1-11
We used in-situ hybridization to analyze the expression patterns of three known members (a, b and c) of the RGM (“repulsive guidance molecule”) gene family and of the RGMa receptor neogenin in a glaucoma mouse model (DBA/2J strain) and the C57BL/
Autor:
Peter Szurman, Patrice Decker, Salvatore Grisanti, Sabine Aisenbrey, Karl U. Bartz-Schmidt, Gesine B. Jaissle, Sigrid Henke-Fahle, Radoslaw Kaczmarek, Martin S. Spitzer
Publikováno v:
Experimental Eye Research. 83:584-592
The aim of the study was to evaluate the antiproliferative and cytotoxic properties of triamcinolone acetonide (TA) on human retinal pigment epithelium cells (ARPE19) and the role of epicellular crystalline deposits. Monolayer cultures of ARPE19 cell
Autor:
Focke Ziemssen, K. Petermeier, Olcay Tatar, Michael Völker, Karl Ulrich Bartz-Schmidt, Werner Inhoffen, Salvatore Grisanti, Sigrid Henke-Fahle, Silvia Bopp, Faik Gelisken, B. A. Lafaut
Publikováno v:
British Journal of Ophthalmology. 90:1034-1039
To evaluate the impact of verteporfin photodynamic therapy (PDT) on the induction of apoptosis in choroidal neovascular membranes (CNV) secondary to age related macular degeneration.Retrospective review of 22 surgically excised CNV. 12 of these patie
Autor:
Salvatore Grisanti, Serap Canbek, Anne Adam, B. A. Lafaut, Faik Gelisken, Karl Ulrich Bartz-Schmidt, Edwin Kaiserling, Jolanta Oficjalska-Mlynczak, Peter Szurman, Sigrid Henke-Fahle
Publikováno v:
Experimental Eye Research. 78:207-213
Endoglin (CD105) is a membrane protein involved in the TGF-β receptor signalling pathway with predominant expression by proliferating endothelial cells. The aim of this study is to analyze the expression of Endoglin in choroidal neovascularization m
Publikováno v:
Molecular and Cellular Neuroscience. 22:319-330
Axons fail to regenerate in the central nervous system after injury. Chondroitin sulfate proteoglycans (CSPG) expressed in the scar significantly contribute to the nonpermissive properties of the central nervous system environment. To examine the inh
Characterization of a New Brain-Derived Proteoglycan Inhibiting Retinal Ganglion Cell Axon Outgrowth
Publikováno v:
Molecular and Cellular Neuroscience. 18:541-556
A proteoglycan was identified and isolated from physiological saline extracts of chick embryo brains by using a new monoclonal antibody (hybridoma clone mab Te38). The purified proteoglycan displayed an apparent molecular mass of 2500-3500 kDa, which
Autor:
Gerhard Fierlbeck, K. U. Bartz-Schmidt, Anja Ulmer, Gesine B. Jaissle, Peter Szurman, S Aisenbrey, Sigrid Henke-Fahle
Publikováno v:
Klinische Monatsblätter für Augenheilkunde. 226:70-72