Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sigrid Deller"'
Autor:
EVA SVEHLIKOVA, KRISTINE NISS ARFELT, ROMAN CAILLETEAU, SIGRID DELLER, KAREN MARGRETE THOMSEN, MARLIES HART, INES MURSIC, THOMAS PIEBER, HANNE HAAHR
Publikováno v:
Diabetes. 71
Insulin icodec is a basal insulin in development for once-weekly (OW) dosing. The aim of this study was to compare the hypoglycemia frequency and response after icodec vs. insulin glargine U100 (IGlar) overdosing. In a randomized, open-label, two-per
Autor:
Chandrappa Manu, Eva Svehlikova, KristineNiss Arfelt, Roman Cailleteau, Sigrid Deller, KarenMargrete Thomsen, Marlies Hart, Ines Mursic, Thomas Pieber, Hanne Haahr
Publikováno v:
Indian Journal of Endocrinology and Metabolism. 26:67
Autor:
J Priya, Eva Svehlikova, KristineNiss Arfelt, Roman Cailleteau, Sigrid Deller, KarenMargrete Thomsen, Marlies Hart, Ines Mursic, Thomas Pieber, Hanne Haahr
Publikováno v:
Indian Journal of Endocrinology and Metabolism. 26:57
Autor:
Hanne Haahr, Stefan Korsatko, Tim Heise, Sigrid Deller, Hans Veit Coester, Marcus Hompesch, Stine Segel, R. Kapur, Carsten Roepstorff, Leszek Nosek
Publikováno v:
Journal of Diabetes. 8:132-138
Background Various factors influence the pharmacokinetic and pharmacodynamic properties of insulin analogs. The aim of the present study was to determine time to steady state of insulin degludec (IDeg), a basal insulin analog with an ultralong durati
Autor:
K. Glettler, Thomas R. Pieber, Stefan Korsatko, Gerlies Treiber, Sigrid Deller, Gerd Koehler, Julia K. Mader, Martina Urschitz, Flemming L. Søndergaard, Michael Wolf, H. Hastrup, Hanne Haahr
Publikováno v:
Drugs & Aging
Background Management of diabetes in elderly subjects is complex and careful management of glucose levels is of particular importance in this population because of an increased risk of diabetes-related complications and hypoglycaemia. Objective The a
Autor:
Stefan Korsatko, Sigrid Deller, Thomas R. Pieber, Susanne Boysen, Selma Mautner, Julia K. Mader, Thomas Augustin, Thomas Birngruber, Gerd Köhler, Frank Sinner
Publikováno v:
Diabetes Care
OBJECTIVE We investigated the impact of two different injection strategies on the pharmacokinetics and pharmacodynamics of insulin aspart in vivo in an open-label, two-period crossover study and verified changes in the surface-to-volume ratio ex vivo
Autor:
Helmut Schwab, Giuliano Freddi, Ruth Birner-Gruenberger, Georg M. Guebitz, Thomas Weber, Ilaria Donelli, Sigrid Deller, Karl-Heinz Maurer, Regina Leber, Peter Remler, Inge Eiteljoerg, Petra Siegert, Enrique Herrero Acero, Sonja Heumann, Katrin Greimel, Eva Trotscha, Doris Ribitsch
Publikováno v:
Biotechnology Progress. 27:951-960
From a screening on agar plates with bis(benzoyloxyethyl) terephthalate (3PET), a Bacillus subtilis p-nitrobenzylesterase (BsEstB) was isolated and demonstrated to hydrolyze polyethyleneterephthalate (PET). PET-hydrolase active strains produced clear
Autor:
Karl Lohner, Peter Macheroux, Sigrid Deller, Nicole Staunig, Bruce A. Palfey, Ilian Jelesarov, Karl Gruber, Alexandra Binter
Publikováno v:
FEBS Journal. 276:5263-5274
YhdA, a thermostable NADPH:FMN oxidoreductase from Bacillus subtilis, reduces quinones via a ping-pong bi-bi mechanism with a pronounced preference for NADPH. The enzyme occurs as a stable tetramer in solution. The two extended dimer surfaces are pac
Autor:
Ivo Tews, Marco Strohmeier, Silvia Wallner, Peter Macheroux, Sigrid Deller, Irmgard Sinning, Karsten Rippe, Martina Neuwirth, Volker Windeisen
Publikováno v:
FEBS Letters. 583:2179-2186
The universal enzymatic cofactor vitamin B6 can be synthesized as pyridoxal 5-phosphate (PLP) by the glutamine amidotransferase Pdx1. We show that Saccharomyces cerevisiae Pdx1 is hexameric by analytical ultracentrifugation and by crystallographic 3D
Autor:
Nina Jajčanin-Jozić, Pravas Kumar Baral, Karl Gruber, Peter Macheroux, Sigrid Deller, Marija Abramić
Publikováno v:
The journal of biological chemistry 283, 22316-22324 (2008). doi:10.1074/jbc.M803522200
Dipeptidyl-peptidases III (DPP III) are zinc-dependent enzymes that specifically cleave the first two amino acids from the N terminus of different length peptides. In mammals, DPP III is associated with important physiological functions and is a pote