Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Sigrid A, Otto"'
Autor:
Sara P H van den Berg, Lyanne Y Derksen, Julia Drylewicz, Nening M Nanlohy, Lisa Beckers, Josien Lanfermeijer, Stephanie N Gessel, Martijn Vos, Sigrid A Otto, Rob J de Boer, Kiki Tesselaar, José A M Borghans, Debbie van Baarle
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010152 (2021)
Cytomegalovirus (CMV) infection has a major impact on the T-cell pool, which is thought to be associated with ageing of the immune system. The effect on the T-cell pool has been interpreted as an effect of CMV on non-CMV specific T-cells. However, it
Externí odkaz:
https://doaj.org/article/75fa94e444bf43b9ac20d94ea3bccc0d
Autor:
Mariona Baliu-Piqué, Vera van Hoeven, Julia Drylewicz, Lotte E van der Wagen, Anke Janssen, Sigrid A Otto, Menno C van Zelm, Rob J de Boer, Jürgen Kuball, Jose AM Borghans, Kiki Tesselaar
Publikováno v:
eLife, Vol 10 (2021)
Lymphocyte numbers need to be quite tightly regulated. It is generally assumed that lymphocyte production and lifespan increase homeostatically when lymphocyte numbers are low and, vice versa, return to normal once cell numbers have normalized. This
Externí odkaz:
https://doaj.org/article/284e6b966f534a63b87407d15f4ffc95
Autor:
Frank Miedema, Marie José Kersten, Kiki Tesselaar, Marinus H.J. van Oers, Eric Eldering, Shulamiet Wittebol, An F.C. Ruiter, Mariëtte A.T. Ackermans, Nienke Vrisekoop, José A.M. Borghans, A. Jaspers, Sigrid A. Otto, Arnon P. Kater, Rogier van Gent
Supplementary Table 2 from In vivo Dynamics of Stable Chronic Lymphocytic Leukemia Inversely Correlate with Somatic Hypermutation Levels and Suggest No Major Leukemic Turnover in Bone Marrow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af5067ebfd6af2423cb1edbe82d068a
https://doi.org/10.1158/0008-5472.22376618.v1
https://doi.org/10.1158/0008-5472.22376618.v1
Autor:
Frank Miedema, Marie José Kersten, Kiki Tesselaar, Marinus H.J. van Oers, Eric Eldering, Shulamiet Wittebol, An F.C. Ruiter, Mariëtte A.T. Ackermans, Nienke Vrisekoop, José A.M. Borghans, A. Jaspers, Sigrid A. Otto, Arnon P. Kater, Rogier van Gent
Supplementary Table 1 from In vivo Dynamics of Stable Chronic Lymphocytic Leukemia Inversely Correlate with Somatic Hypermutation Levels and Suggest No Major Leukemic Turnover in Bone Marrow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24843dae65092c87893c3f1be768c988
https://doi.org/10.1158/0008-5472.22376621.v1
https://doi.org/10.1158/0008-5472.22376621.v1
Autor:
Julia Drylewicz, Nienke Vrisekoop, Tendai Mugwagwa, Anne Bregje de Boer, Sigrid A Otto, Mette D Hazenberg, Kiki Tesselaar, Rob J de Boer, José A M Borghans
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152513 (2016)
Naive T cells in untreated HIV-1 infected individuals have a reduced T-cell receptor excision circle (TREC) content. Previous mathematical models have suggested that this is due to increased naive T-cell division. It remains unclear, however, how red
Externí odkaz:
https://doaj.org/article/48814518673f4b4e8280c1b76d0e3081
Autor:
Mariona, Baliu-Piqué, Julia, Drylewicz, Xiaoyan, Zheng, Lisa, Borkner, Arpit C, Swain, Sigrid A, Otto, Rob J, de Boer, Kiki, Tesselaar, Luka, Cicin-Sain, José A M, Borghans
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 208(4)
The potential of memory T cells to provide protection against reinfection is beyond question. Yet, it remains debated whether long-term T cell memory is due to long-lived memory cells. There is ample evidence that blood-derived memory phenotype CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f540d4d935976bcb959c4f38b31c0b0a
https://pubmed.ncbi.nlm.nih.gov/35091435
https://pubmed.ncbi.nlm.nih.gov/35091435
Autor:
Steven F L van Lelyveld, Julia Drylewicz, Maaike Krikke, Ellen M Veel, Sigrid A Otto, Clemens Richter, Robin Soetekouw, Jan M Prins, Kees Brinkman, Jan Willem Mulder, Frank Kroon, Ananja Middel, Jori Symons, Annemarie M J Wensing, Monique Nijhuis, José A M Borghans, Kiki Tesselaar, Andy I M Hoepelman, MIRS study group
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132430 (2015)
The immunomodulatory effects of the CCR5-antagonist maraviroc might be beneficial in patients with a suboptimal immunological response, but results of different cART (combination antiretroviral therapy) intensification studies are conflicting. Theref
Externí odkaz:
https://doaj.org/article/3822b11de4db4781b6dfc3e0e6f04736
Autor:
Lotte van der Wagen, Julia Drylewicz, Mariona Baliu-Piqué, José Borghans, Sigrid A. Otto, Vera van Hoeven, Jürgen Kuball, Rob J. de Boer, Kiki Tesselaar, Menno C. van Zelm, Anke Janssen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc462735fd4a5e38ab7fc32b671706f
https://doi.org/10.7554/elife.59775.sa2
https://doi.org/10.7554/elife.59775.sa2
Autor:
Lotte van der Wagen, Vera van Hoeven, Kiki Tesselaar, Menno C. van Zelm, Anke Janssen, Mariona Baliu-Piqué, Sigrid A. Otto, José A. M. Borghans, Julia Drylewicz, Rob J. de Boer, Jürgen Kuball
Lymphocyte numbers need to be quite tightly regulated. It is generally assumed that lymphocyte production and survival rates increase homeostatically when lymphocyte numbers decrease. This widely-accepted concept is largely based on experiments in mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86b1f15a7d4a44999a0c287545bac10
https://doi.org/10.1101/2020.04.24.20078295
https://doi.org/10.1101/2020.04.24.20078295
Publikováno v:
Immunology Letters, 210, 29. Elsevier
The maintenance and dynamics of memory T-cells in the bone marrow are a matter of ongoing debate. It has been suggested that memory T-cells in the bone marrow are maintained as long-lived, quiescent cells. We have recently shown that memory T-cells i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3f14aa4361860003cec948da18340a
https://pubmed.ncbi.nlm.nih.gov/31004681
https://pubmed.ncbi.nlm.nih.gov/31004681