Tapered discontinuation vs. maintenance therapy of antipsychotic medication in patients with first-episode schizophrenia: Obstacles, findings, and lessons learned in the terminated randomized clinical trial TAILOR

Autor: Anne Emilie Stürup, Carsten Hjorthøj, Nikolai Albert, Signe Dolmer, Merete Birk, Bjørn H. Ebdrup, Lene Falgaard Eplov, Heidi Jensen, Ditte Lammers Vernal, Helene Speyer, Ole Mors, Merete Nordentoft

Publikováno v: Frontiers in Psychiatry, Vol 13 (2022)

AimEvidence is insufficient regarding the consequences of discontinuing vs. maintaining antipsychotic medication in patients with first-episode schizophrenia. Our aim was to examine tapered discontinuation vs. maintenance treatment regarding remissio

Externí odkaz: https://doaj.org/article/beac198f111b44f9820b2a1cba262aea

A feasibility study of the transdiagnostic self-injury interview

Autor: Jesper Nørgaard Kjær, Tine Holm, Trine Ellegaard, Sissel Madsen, Eva Lorentzen, Ane Bjerg Christensen, Vibeke Bliksted, Ole Mors, Signe Dolmer

Publikováno v: Kjær, J N, Holm, T, Ellegaard, T, Madsen, S, Lorentzen, E, Christensen, A B, Bliksted, V, Mors, O & Dolmer, S 2023, ' A feasibility study of the transdiagnostic self-injury interview ', Nordic Journal of Psychiatry, pp. 1-10 . https://doi.org/10.1080/08039488.2023.2192212

OBJECTIVES: The Transdiagnostic Self-injury Interview (TSI) is a new measure that assesses the onset, frequency, methods, and severity of non-suicidal self-injury. The aims were to demonstrate the feasibility of a TSI validation study, and to investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c555bbda244fa135a3038f12a13cfe5
https://pure.au.dk/portal/da/publications/a-feasibility-study-of-the-transdiagnostic-selfinjury-interview(02ad1c42-e05d-44be-8c41-ad8fa2b27dc9).html

TAILOR – tapered discontinuation versus maintenance therapy of antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorder in remission of psychotic symptoms: study protocol for a randomized clinical trial

Autor: Heidi Dorthe Jensen, Merete Birk, Bjørn H Ebdrup, Nikolai Albert, Merete Nordentoft, Mai Nielsen, Anne Emilie Stürup, Carsten Hjorthøj, Lene Falgaard Eplov, Ole Mors, Signe Dolmer

Publikováno v: Trials
Trials, Vol 18, Iss 1, Pp 1-12 (2017)
Stürup, A E, Jensen, H D, Dolmer, S, Birk, M, Albert, N, Nielsen, M, Hjorthøj, C, Eplov, L, Ebdrup, B H, Mors, O & Nordentoft, M 2017, ' TAILOR-tapered discontinuation versus maintenance therapy of antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorder in remission of psychotic symptoms : study protocol for a randomized clinical trial ', Current Controlled Trials in Cardiovascular Medicine
, vol. 18 . https://doi.org/10.1186/s13063-017-2172-4
Stürup, A E, Jensen, H D, Dolmer, S, Birk, M, Albert, N, Nielsen, M, Hjorthøj, C, Eplov, L, Ebdrup, B H, Mors, O & Nordentoft, M 2017, ' TAILOR-tapered discontinuation versus maintenance therapy of antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorder in remission of psychotic symptoms : study protocol for a randomized clinical trial ', Trials, vol. 18, 445 . https://doi.org/10.1186/s13063-017-2172-4

Background The aim of the TAILOR trial is to investigate the effect of closely monitored tapering/discontinuation versus maintenance therapy with antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a8400f11b002c27d479e30761db85e
http://europepmc.org/articles/PMC5622425