Zobrazeno 1 - 10 of 1 044 pro vyhledávání: '"Signaling in Selected Disciplines"'
1
Suppression of AP1 Transcription Factor Function in Keratinocyte Suppresses Differentiation
Autor: Gautam Adhikary, Richard L. Eckert, Wen Xu, Ellen A. Rorke, Yap Ching Chew, Bingshe Han
Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36941 (2012)
Our previous study shows that inhibiting activator protein one (AP1) transcription factor function in murine epidermis, using dominant-negative c-jun (TAM67), increases cell proliferation and delays differentiation. To understand the mechanism of act
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ad3e5077a9d898978fe9edfcd099c0
http://europepmc.org/articles/PMC7877661
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2
Expression of Concern: ZEB2 Mediates Multiple Pathways Regulating Cell Proliferation, Migration, Invasion, and Apoptosis in Glioma
Publikováno v: PLoS ONE
Background The aim of the present study was to analyze the expression of Zinc finger E-box Binding homeobox 2 (ZEB2) in glioma and to explore the molecular mechanisms of ZEB2 that regulate cell proliferation, migration, invasion, and apoptosis. Metho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::60d1748f6052289681b94ca779ad9fb5
http://europepmc.org/articles/PMC7112199
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3
Retraction: miR-221 Promotes Tumorigenesis in Human Triple Negative Breast Cancer Cells
Publikováno v: PLoS ONE
Patients with triple-negative breast cancers (TNBCs) typically have a poor prognosis. TNBCs are characterized by their resistance to apoptosis, aggressive cellular proliferation, migration and invasion, and currently lack molecular markers and effect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3ce48d996f8aadd3dc38ed67173f1aa
https://pubmed.ncbi.nlm.nih.gov/23637992
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4
A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors
Autor: John R. Young, Marylene Y. Peroval, Adrian Smith, Amy Boyd
Publikováno v: PLoS ONE, Vol 8, Iss 2, p e51243 (2013)
PLoS ONE
Toll-like Receptors (TLR) are phylogenetically conserved transmembrane proteins responsible for detection of pathogens and activation of immune responses in diverse animal species. The stimulation of TLR by pathogen-derived molecules leads to the pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08c89d83d04a6028ee864b1d2933787
https://doi.org/10.1371/journal.pone.0051243
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5
Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression
Autor: Buss, H, Handschick, K, Jurrmann, N, Pekkonen, P, Beuerlein, K, Müller, H, Wait, R, Saklatvala, J, Ojala, PM, Schmitz, ML, Naumann, M, Kracht, M
Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e51847 (2012)
Nuclear factor kappa-B (NF-κB) activates multiple genes with overlapping roles in cell proliferation, inflammation and cancer. Using an unbiased approach we identified human CDK6 as a novel kinase phosphorylating NF-κB p65 at serine 536. Purified a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::110dfb522e2af814da67a5bca1a95688
https://ora.ox.ac.uk/objects/uuid:46ac7aa8-4528-4b4d-902d-cfb9c59aebf2
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6
Growth Conditions Determine the DNF2 Requirement for Symbiosis
Autor: Fathi Berrabah, Marie Bourcy, Pascal Ratet, Benjamin Gourion, Alexis Eschstruth, Samuel Mondy, Anne Cayrel
Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (3), pp.e91866. ⟨10.1371/journal.pone.0091866⟩
Plos One 3 (9), 10 p.. (2014)
PLoS ONE, 2014, 9 (3), pp.e91866. ⟨10.1371/journal.pone.0091866⟩
PLoS ONE, Vol 9, Iss 3, p e91866 (2014)
International audience; Rhizobia and legumes are able to interact in a symbiotic way leading to the development of root nodules. Within nodules, rhizobia fix nitrogen for the benefit of the plant. These interactions are efficient because spectacularl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4babdd901a6dacaa84a8fdac7f8af775
https://hal-cnrs.archives-ouvertes.fr/hal-02410365
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7
Attenuation of Hedgehog Acyltransferase-Catalyzed Sonic Hedgehog Palmitoylation Causes Reduced Signaling, Proliferation and Invasiveness of Human Carcinoma Cells
Autor: Christopher P. Palmer, Anthony I. Magee, Shu Chun Chang, Antonios D. Konitsiotis, Biljana Jovanovic, Naoko Masumoto, John R. Couchman, Edward W. Tate, Paulina Ciepla
Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e89899 (2014)
Overexpression of Hedgehog family proteins contributes to the aetiology of many cancers. To be highly active, Hedgehog proteins must be palmitoylated at their N-terminus by the MBOAT family multispanning membrane enzyme Hedgehog acyltransferase (Hhat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec345d4c9cd142799d314c7e2495a60
http://europepmc.org/articles/PMC3946499
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8
Serum Amyloid A in the Placenta and Its Role in Trophoblast Invasion
Autor: Fabíola Branco Filippin-Monteiro, Estela Bevilacqua, Ana Campa, Edson Mendes de Oliveira, Alexandre Urban Borbely, Isabella Rodrigues Fernandes, Rodrigo Ruano, Silvana Sandri, Marcelo Zugaib, Franciele Hinterholz Knebel
Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e90881 (2014)
The serum amyloid A (SAA) protein is known to function in the acute phase response and immunoregulation. Recently, SAA has been shown to be involved in cell proliferation, differentiation and migratory behavior in different cell types. Here, we evalu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbfebc2c7a8e9b2860ca3649a957795
http://europepmc.org/articles/PMC3948705
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9
Cytohesins/ARNO: the function in colorectal cancer cells
Autor: Dong Xu, Wenhong Xu, Jun Zhou, Junfeng Sun, Tao Pan, Yiwang Hu, Suzhan Zhang, Jiyi Hu, Shu Zheng, Zhigang Chen
Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e90997 (2014)
Epidermal growth factor (EGF) and insulin-like growth factor-I (IGF-I) are critical regulators of cell differentiation, survival, proliferation, and migration in cancers. This study found that ARNO (cytohesin-2), an activator of the EGF and IGF-I pat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26a168d6ed547cac7301ce25cc488ea
http://europepmc.org/articles/PMC3950297
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10
The Adenylyl Cyclase Plays a Regulatory Role in the Morphogenetic Switch from Vegetative to Pathogenic Lifestyle of Fusarium graminearum on Wheat
Autor: Demet Firat, Jörg Bormann, Marike Johanne Boenisch, Wilhelm Schäfer, Elena Brückner
Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e91135 (2014)
Cyclic 3′,5′-adenosine monophosphate (cAMP) is a nucleotide derived from adenosine triphosphate that acts as a second messenger throughout all kingdoms. Intracellular cAMP levels are synthesized by a membrane-bound protein, the adenylyl cyclase.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc15af574707b929cb5fc007f73bb84
http://europepmc.org/articles/PMC3946419
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